Naional Cancer Institute, Naitonal Clinical Trials Network U10 Lead Academic Site

国家癌症研究所、国家临床试验网络 U10 首席学术网站

• 批准号: 8846075
• 负责人: STEVEN R ALBERTS
• 金额: $ 129.59万
• 依托单位: MAYO CLINIC ROCHESTER
• 依托单位国家: 美国
• 财政年份: 2014
• 资助国家: 美国
• 起止时间: 2014-05-06 至 2019-02-28
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8846075
• 关键词: Address; American College of Radiology Imaging Network; American College of Surgeons Oncology Group; Cancer and Leukemia Group B; Clinic; Clinic Activity; Clinical Research; Clinical Trials; Clinical Trials Network; Collection; Data; Eastern Cooperative Oncology Group; Goals; Grant; Gynecologic Oncology Group; Health; Image; Institutes; Institution; Journals; Lead; Leadership; Malignant Neoplasms; Mayo Clinic Cancer Center; North Central Cancer Treatment Group; Patients; Publishing; Radiation Therapy Oncology Group; Reporting; Research; Research Infrastructure; Research Personnel; Role; Site; Structure; Support System; United States National Institutes of Health; Work; base; burden of illness; member

DESCRIPTION (provided by applicant): Mayo Clinic has had a long-standing commitment to support and lead NCTN clinical trials through NCCTG, ECOG, ACOSOG, ACRIN, RTOG, and GOG. Mayo Clinic served as the founding institution and operational base for NCCTG until its merger with CALGB and ACOSOG to form the Alliance. Mayo investigators have also had leadership roles in these groups as well as in the newly forming groups (Alliance, ECOG-ACRIN, and NRG). The current clinical research structure within the Mayo Clinic Cancer Center (MCCC) continues to prioritize NIH sponsored trial, including NCTN trials, over other trials. Support systems are in place within the MCCC to maximize accrual and to support the translational components of these trials, including biospecimen collection and imaging. Mayo investigators also remained very active in trial leadership. Mayo investigators have also been very effective in utilizing data and biospecimens collected from NCTN trials to address important and relevant research questions. Through this commitment to research, Mayo investigators have published multiple reports in high impact journals and successfully obtained multiple grants, including R01 grants, to support this work.

描述（由申请人提供）：梅奥诊所长期致力于通过 NCCTG、ECOG、ACOSOG、ACRIN、RTOG 和 GOG 支持和领导 NCTN 临床试验。在与 CALGB 和 ACOSOG 合并组建联盟之前，梅奥诊所一直是 NCCTG 的创始机构和运营基地。梅奥研究人员还在这些团体以及新成立的团体（Alliance、ECOG-ACRIN 和 NRG）中发挥了领导作用。梅奥诊所癌症中心 (MCCC) 目前的临床研究结构继续优先考虑 NIH 资助的试验，包括 NCTN 试验，而不是其他试验。 MCCC 内设有支持系统，以最大限度地提高应计费用并支持这些试验的转化部分，包括生物样本采集和成像。梅奥研究人员在试验领导中也仍然非常活跃。梅奥研究人员在利用 NCTN 试验收集的数据和生物样本来解决重要且相关的研究问题方面也非常有效。通过对研究的承诺，梅奥研究人员在高影响力期刊上发表了多份报告，并成功获得了多项资助（包括 R01 资助）来支持这项工作。