Mentoring in Cardiovascular Biology

心血管生物学辅导

• 批准号: 9126990
• 负责人: DANIEL R KAPUSTA
• 金额: $ 109.6万
• 依托单位: LSU HEALTH SCIENCES CENTER
• 依托单位国家: 美国
• 财政年份: 2014
• 资助国家: 美国
• 起止时间: 2014-09-09 至 2019-07-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/9126990
• 关键词: American Heart Association; Animal Model; Area; Award; Biology; Blood Vessels; Cardiovascular Diseases; Cardiovascular system; Career Choice; Cause of Death; Cell physiology; Centers of Research Excellence; Collaborations; Core Facility; Disease Progression; Environment; Extramural Activities; Fostering; Funding; Grant; Health Sciences; Human; In Vitro; Individual; Laboratories; Lead; Louisiana; Mentors; Mission; Molecular; Molecular Analysis; Phase; Pilot Projects; Process; Research; Research Infrastructure; Research Personnel; Research Training; Scientific Advances and Accomplishments; Scientist; Translational Research; United States; United States National Institutes of Health; Universities; Woman; men; multidisciplinary; programs; stem

The objective of our Phase III Center of Biomedical Research Excellence (COBRE) program is to continue to provide the strong infrastructure, core laboratory support, and collegial scientific environment necessary to mentor outstanding investigators and foster collaborations within the multidisciplinary and interdepartmental effort in cardiovascular biology at the Louisiana State University Health Sciences Center-New Orleans (LSUHSC-NO). One of the top priorities of our Phase I and Phase II COBRE program has been to increase the number of NIH-R01 grants in cardiovascular biology by transitioning Junior Investigators from COBRE support to R01-funded status and to launch these individuals on a successful research career path. This effort has been one major step to a broad institutional initiative to develop a Cardiovascular Center of Excellence at LSUHSC. Over the last 10 years of funding, we built three scientific core facilities that have been instrumental in advancing the scientific programs of COBRE and fellow researchers at LSUHSC. We have matriculated 16 outstanding Jr. Investigators through our program. Of these, 14 received extramural grant awards from NIH and/or the American Heart Association stemming from their COBRE projects. Thus, Phase III support is required to sustain the strong infrastructure and mentoring environment we have developed over the past 10 years as we finalize the transition of our program from COBRE to Institutional support. The following are the Specific Aims of the Phase 111 program: 1) To provide support to sustain and enhance the infrastructure and use of COBRE Core Facilities, which have been pivotal to the function of our Center's cardiovascular research mission at LSUHSC, 2) To further increase the critical mass of investigators at LSUHSC with research programs in the area of cardiovascular disease through the support of COBRE Pilot Projects and the mentoring mission of our Center, 3) To expand the thematic, multidisciplinary and interdepartmental research program in cardiovascular biology which fosters collaborative relationships between basic and clinician-scientists, 4). To finalize the transition from a COBRE supported program to a nationally recognized, interdisciplinary Center of Excellence with state and federal funding.

我们的第三阶段生物医学卓越研究中心 (COBRE) 计划的目标是继续 提供必要的强大基础设施、核心实验室支持和大学科学环境 指导优秀的研究人员并促进多学科和跨部门的合作 路易斯安那州立大学新奥尔良健康科学中心在心血管生物学方面的努力 （LSUHSC-NO）。我们第一阶段和第二阶段 COBRE 计划的首要任务之一是增加 由 COBRE 转任初级研究员而获得的 NIH-R01 心血管生物学资助数量 支持 R01 资助的身份，并帮助这些人走上成功的研究职业道路。这 这一努力是向建立心血管中心的广泛机构倡议迈出的重要一步 路易斯安那州立大学HSC 的卓越表现。在过去 10 年的资助中，我们建造了三个科学核心设施， 在推进 COBRE 和 LSUHSC 的研究人员的科学项目方面发挥了重要作用。我们 通过我们的项目已经录取了 16 名杰出的初级研究员。其中 14 人获得校外 NIH 和/或美国心脏协会授予其 COBRE 项目的奖项。因此， 需要第三阶段的支持来维持我们拥有的强大的基础设施和指导环境 随着我们完成项目从 COBRE 到机构的过渡，我们在过去 10 年中不断发展 支持。以下是第 111 阶段计划的具体目标： 1) 提供支持以维持和 加强 COBRE 核心设施的基础设施和使用，这对于我们的功能至关重要 路易斯安那州立大学健康科学中心 (LSUHSC) 中心的心血管研究任务，2) 进一步提高心血管研究的临界质量 LSUHSC 的研究人员通过支持在心血管疾病领域开展研究项目 COBRE 试点项目和我们中心的指导任务，3) 扩大专题、多学科 心血管生物学跨部门研究计划，促进合作 基础和临床医生-科学家之间的关系，4)。完成从 COBRE 支持的过渡 计划在州和联邦的资助下建立一个全国认可的跨学科卓越中心。