Testing the feasibility and preliminary efficacy of a psychological and behavioral intervention to promote physical activity after weight loss surgery

测试减肥手术后通过心理和行为干预促进身体活动的可行性和初步效果

• 批准号: 10853260
• 负责人: Emily Feig
• 金额: $ 7.56万
• 依托单位: MASSACHUSETTS GENERAL HOSPITAL
• 依托单位国家: 美国
• 财政年份: 2020
• 资助国家: 美国
• 起止时间: 2020-07-01 至 2025-06-30
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10853260
• 关键词: Achievement; Address; Adherence; Administrative Supplement; Behavior Therapy; Body Weight decreased; Chronic Disease; Clinical; Emotional; Evidence based intervention; Exercise; Free Will; Funding; General Hospitals; Goals; Health; Health behavior; Individual; Intervention; Interview; Maintenance; Massachusetts; Maternity leave; Medicine; Mentored Patient-Oriented Research Career Development Award; Mentors; Mentorship; Metabolic; Methods; Morbid Obesity; Obesity; Operative Surgical Procedures; Outcome; Patients; Peer Review; Personal Satisfaction; Physical activity; Psychology; Publications; Quality of life; Randomized, Controlled Trials; Recommendation; Research; Research Personnel; Running; Testing; Time; Training; Treatment Efficacy; United States National Institutes of Health; Weight; Well in self; bariatric surgery; catalyst; design; effective therapy; efficacy testing; emotional experience; exercise intervention; feasibility testing; high risk population; improved; meetings; motivational enhancement therapy; obese patients; positive emotional state; prevent; programs; psychologic; recruit; remote delivery

PROJECT SUMMARY/ABSTRACT Candidate. This administrative supplement will allow Dr. Feig to continue toward her path of becoming an independent investigator with expertise in developing and testing evidence-based interventions to improve health and well-being in patients with obesity. Her achievements thus far demonstrate her promise as a clinical researcher (39 peer-reviewed publications), and with the additional training and mentorship she is receiving through this K23 award she will contribute significantly to efforts to reduce the burden of obesity and improve quality of life for those with obesity. Training Plan. Dr. Feig will continue with her proposed training plan after her return from maternity leave, which will be possible with the additional support that will free up for time for her to focus on training. This will include attending ongoing research seminars at Massachusetts General Hospital, meeting regularly with her mentors, Dr. Huffman, Dr. Thorndike, Dr. Psaros, and Dr. Healy, and continuing to participate in the Harvard Catalyst GRASP Program. She will also, as planned, take the three-day Blackburn Course in Obesity Medicine, apply for the ORBIT Institute Developing Behavioral Treatments to Improve Health NIH-funded short course in the spring of 2024, and will take an RCR refresher course. Background. Metabolic/bariatric surgery is the most effective treatment available for severe obesity, yet about 25% of patients do not achieve sustained meaningful weight loss after surgery. Both adherence to health behaviors such as physical activity and psychological well-being are associated with weight loss maintenance after surgery, but up to 90% of patients do not meet physical activity recommendations post-surgery. A lack of psychological well-being may contribute to low levels of physical activity, especially if patients have negative emotional associations with physical activity. Interventions that consider this psychological component are needed to improve physical activity adherence in patients after metabolic/bariatric surgery who are struggling to exercise consistently. Research Strategy. To address this gap, this K23 study is using a mixed methods design to adapt and test a positive psychology-motivational interviewing physical activity intervention in patients post-surgery from the Massachusetts General Hospital Weight Center. After completing qualitative interviews with 23 patients to better understand emotional experiences related to physical activity and a proof-of-concept trial (N=12) of the newly adapted intervention based on these interviews, a pilot randomized controlled trial is currently in progress (target N=58) to test feasibility, acceptability, and preliminary efficacy of the intervention. The proposed administrative supplement will allow this trial to continue to run efficiently during and after Dr. Feig’s maternity leave to meet recruitment goals, laying the groundwork for an R01 application to test efficacy of the intervention in a full-scale trial.

项目摘要/摘要 候选人。这种行政补充剂将使Feig博士继续迈向她成为一个 独立研究者具有开发和测试基于证据的干预措施的专业知识以改进 肥胖患者的健康和福祉。到目前为止，她的成就表明了她作为临床的承诺 研究人员（39个同行评审的出版物），她正在接受额外的培训和精神训练 通过这个K23奖，她将为减少肥胖的燃烧和改善做出重大贡献 肥胖者的生活质量。 培训计划。 Feig博士将在育产假返回后继续她的拟议培训计划， 通过额外的支持，这将是可能的，她可以腾出时间来专注于培训。这会 包括参加马萨诸塞州总医院正在进行的研究下水道，定期与她会面 导师，霍夫曼博士，桑迪克博士，帕萨罗斯博士和希利博士，并继续参加哈佛大学 催化剂掌握程序。按计划，她还将参加为期三天的肥胖症布莱克本课程 医学，申请开发行为治疗的轨道研究所，以改善健康NIH资助的短期 课程在2024年春季，将参加RCR进修课程。 背景。代谢/减肥手术是可用于严重肥胖症的最有效治疗方法 25％的患者在手术后没有实现有意义的体重减轻。两者都坚持健康 体育活动和心理健康等行为与减肥维持有关 手术后，但是多达90％的患者在手术后不符合身体活动建议。缺乏 心理健康可能会导致体育锻炼水平较低，尤其是在患者阴性的情况下 与体育锻炼的情感联系。认为这种心理组成部分的干预措施是 需要改善苦苦挣扎的代谢/减肥手术后患者的身体活动依从性 持续锻炼。 研究策略。为了解决这一差距，这项K23研究正在使用混合方法设计来适应和测试 心理动机动机访谈在外科手术后进行体育锻炼干预。 马萨诸塞州综合医院体重中心。完成与23位患者进行定性访谈后 更好地了解与体育活动有关的情感经历和概念证明的试验（n = 12） 根据这些访谈，新适应的干预措施，当前是一项飞行员随机对照试验 进度（目标n = 58）以测试干预措施的可行性，可接受性和初步效率。 拟议的行政补充剂将使该试验在Feig博士的期间和之后继续有效地运行 产假以实现招聘目标，为R01申请奠定基础，以测试 干预全面试验。

项目成果

A Qualitative Examination of Emotional Experiences During Physical Activity Post-metabolic/Bariatric Surgery.

• DOI: 10.1007/s11695-021-05807-x
• 发表时间: 2022-03
• 期刊: Obesity surgery
• 影响因子: 2.9
• 作者: Feig EH;Harnedy LE;Golden J;Thorndike AN;Huffman JC;Psaros C
• 通讯作者: Psaros C

Increase in Daily Steps During the Early Phase of a Physical Activity Intervention for Type 2 Diabetes as a Predictor of Intervention Outcome.

• DOI: 10.1007/s12529-021-09966-0
• 发表时间: 2021-12
• 期刊: International journal of behavioral medicine
• 影响因子: 2.7
• 作者: Feig EH;Harnedy LE;Celano CM;Huffman JC
• 通讯作者: Huffman JC

A Positive Emotion-Focused Intervention to Increase Physical Activity After Bariatric Surgery: Protocol for a Pilot Randomized Controlled Trial.

• DOI: 10.2196/39856
• 发表时间: 2022-10-06
• 期刊: JMIR RESEARCH PROTOCOLS
• 影响因子: 1.7
• 作者: Feig, Emily H.;Harnedy, Lauren E.;Thorndike, Anne N.;Psaros, Christina;Healy, Brian C.;Huffman, Jeff C.
• 通讯作者: Huffman, Jeff C.

The role of positive psychological constructs in diet and eating behavior among people with metabolic syndrome: A qualitative study.

• DOI: 10.1177/20551029211055264
• 发表时间: 2022-01
• 期刊: Health psychology open
• 影响因子: 2.9
• 作者: Carrillo A;Feig EH;Harnedy LE;Huffman JC;Park ER;Thorndike AN;Kim S;Millstein RA
• 通讯作者: Millstein RA