STEPS: Supporting Trials for Effective Pain Solutions

步骤：支持有效疼痛解决方案的试验

• 批准号: 10887940
• 负责人: Paul A. Harris
• 金额: $ 66万
• 依托单位: VANDERBILT UNIVERSITY MEDICAL CENTER
• 依托单位国家: 美国
• 财政年份: 2022
• 资助国家: 美国
• 起止时间: 2022-09-24 至 2027-08-31
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10887940
• 关键词: Academic Medical Centers; Acute; Address; Behavioral; Budgets; Clinical Trials Network; Collaborations; Consent; Development; Dropout; Effectiveness; Enrollment; Ensure; Funding; Future; Incentives; Infrastructure; Monitor; Pain; Pain management; Participant; Patient Recruitments; Patients; Persons; Research Personnel; Resources; Services; Sickle Cell; Sickle Cell Anemia; Site; Time; Translational Research; Work; chronic pain; effective intervention; effectiveness research; electronic consent; flexibility; functional improvement; innovation; novel; pain reduction; participant retention; recruit; retention rate; screening; social; study population; tool

Vanderbilt University Medical Center is responding to RFA-TR-22-012 to be the Recruitment Resource Center (RRC). We will work collaboratively with each ERN study team and the other HEAL ERN Resource Centers and continue to develop and monitor comprehensive strategies to address barriers to recruitment and retention in the five funded HEAL pain studies and two additional studies, demonstrate their effectiveness in recruiting diverse participants and broadly disseminate evidence on the most effective approaches to recruitment and retention of people who have pain. Our Recruitment Resource Center application has the following Specific Aims: Specific Aim 1. Develop comprehensive recruitment and retention strategies for HEAL Pain ERN clinical trials to ensure studies efficiently enroll and retain a sufficient number of participants who represent the diversity of the study population Specific Aim 2. Provide centralized participant-centered recruitment and retention services to support HEAL Pain ERN sites in identifying, approaching, screening, consenting, enrolling, and retaining participants. Specific Aim 3. Implement, study, and refine novel recruitment and retention strategies (such as EHR-based participant screening, e-consent, embedding patients on study teams, and behavioral, informational and/or social incentives) and disseminate evidence on the most effective approaches to recruitment and retention of people who have pain. Our collaboration with ERN investigators and integration with the other TIN Resource Centers will maximize the likelihood of successful and timely completion of the HEAL Effectiveness Research Network clinical trials, leading to translation of research findings to the effective interventions and management strategies for pain while, improving functional outcomes, and reducing pain across the continuum of acute to chronic pain.

范德比尔特大学医学中心正在回复 RFA-TR-22-012 作为招聘 资源中心（RRC）。我们将与每个 ERN 研究团队和其他研究团队合作 治愈 ERN 资源中心并继续制定和监控综合战略 解决五项资助的 HEAL 疼痛研究和两项研究中的招募和保留障碍 其他研究证明了它们在招募不同参与者和广泛 传播关于招聘和留住人才的最有效方法的证据 谁有痛苦。 我们的招聘资源中心应用程序有以下具体目标： 具体目标 1. 为 HEAL Pain ERN 制定全面的招募和保留策略 临床试验，以确保研究有效招募并留住足够数量的参与者 代表研究人群的多样性 具体目标 2. 提供以参与者为中心的集中招募和保留服务 支持 HEAL Pain ERN 站点识别、接触、筛选、同意、注册和 留住参与者。 具体目标 3. 实施、研究和完善新颖的招聘和保留策略（例如 基于 EHR 的参与者筛选、电子同意、将患者纳入研究团队，以及 行为、信息和/或社会激励）并传播最有效的证据 招募和留住患有疼痛的人的方法。 我们与 ERN 调查人员的合作以及与其他 TIN 资源中心的整合将 最大限度地提高成功和及时完成 HEAL 有效性研究的可能性 网络临床试验，将研究结果转化为有效的干预措施和 疼痛管理策略，同时改善功能结果并减少整个过程的疼痛 急性到慢性疼痛的连续过程。