Supplement for an intervention to increase HIV Testing Uptake among Adolescents and Young Adults

增加青少年和年轻人艾滋病毒检测率的干预措施的补充

基本信息

批准号：
10881477
负责人：
Amanda Derryck Castel
金额：
$ 10万
依托单位：
MEDIA REZ, LLC
依托单位国家：
美国
项目类别：
财政年份：
2023
资助国家：
美国
起止时间：
2023-08-01 至 2025-03-31
项目状态：
未结题

来源：
https://reporter.nih.gov/project-details/10881477
关键词：
Adolescent and Young Adult Age Attitude Behavior Therapy Caring Development Educational Materials Enrollment Ensure Environment Focus Groups HIV HIV Infections HIV Seronegativity HIV risk Health education Human immunodeficiency virus test Incentives Intervention Knowledge Learning Life Location Medical Modeling Nature Patient Self-Report Phase Play Population Populations at Risk Prevention Preventive care Public Health Randomized Randomized, Controlled Trials Risk Risk Assessment Risk Behaviors Risk Reduction Behavior Technology Testing Time Treatment Efficacy Video Games Youth behavior change cost disorder prevention efficacy evaluation efficacy testing evidence base experience field study innovation multidisciplinary novel prevention service quality assurance recruit sex sexually active simulation game social media testing services testing uptake usability user-friendly

项目摘要

This supplement is to cover expenses that could not have been foreseen at the time of application, including recruiting costs and incentive costs. The study aims to assess the acceptability, usability, and efficacy of using state-of-the-art social media and game technology to increase HIV testing among adolescents and young adults (AYA) ages 13-24. Rates of HIV testing among AYA are low, resulting in high proportions of AYA who are unaware of their HIV infection. Since many AYA are highly engaged with social media and games, these technologies may hold the key to reaching this population. While previous behavior-change games have shown positive results by using the compelling nature of gameplay to make health education entertaining and shift attitudes towards disease prevention, this intervention proposes to incorporate a new innovation which changes the way video games are used to increase HIV testing and linkage to care. The intended result is a novel experience which plays like a game while prompting dialogue about HIV risk assessment, testing, and linkage to prevention in a manner that may be more acceptable to AYA compared to traditional public health messages. We have developed an AYA-informed game in which players can create characters like themselves, model different forms of dating and sex practices to learn the consequences in a simulated, non-health or life-threatening environment, and identify locations for HIV testing and prevention services. We seek to test the efficacy of this game and hypothesize that its use will result in increased HIV testing and lead to a reduction in risky behaviors among AYA at risk for HIV. In this Phase II application, our multidisciplinary team recruited AYA for iterative focus groups to confirm the acceptability of additional game enhancements. We then conducted pilot field testing of the game intervention among AYA (n=10) to ensure usability, acceptability and to conduct quality assurance testing. We now plan to conduct a randomized controlled trial to determine the efficacy of the intervention on HIV testing uptake. We will enroll 300 sexually active HIV negative AYA and randomize them to receive either the life-simulation game intervention or an app which contains HIV educational materials. We will compare self-reported HIV testing between the two study groups. Successful completion of these aims will demonstrate how this product may advance the effective implementation of an evidence-based behavioral intervention for increased HIV testing and linkage to preventive care among youth. Successful development of this core technology could also be revised to be applicable to other medical conditions.

该补助金用于支付当时无法预见的费用申请，包括招聘成本和激励成本。该研究旨在评估使用最先进的社交媒体和游戏技术的可接受性、可用性和功效增加 13-24 岁青少年和年轻人 (AYA) 的艾滋病毒检测。艾滋病毒感染率 AYA 中的检测率较低，导致 AYA 中不知道自己感染艾滋病毒的比例很高感染。由于许多 AYA 高度参与社交媒体和游戏，这些技术可能是接触这一人群的关键。虽然之前的行为改变游戏已经利用游戏的引人入胜的性质进行健康教育，取得了积极的效果这项干预措施旨在娱乐并改变对疾病预防的态度一项新的创新改变了电子游戏增加艾滋病毒的方式测试和与护理的联系。预期的结果是一种像游戏一样的新颖体验同时促进有关艾滋病毒风险评估、检测以及与预防的联系的对话与传统的公共卫生信息相比，这种方式可能更容易被 AYA 接受。我们开发了一款基于 AYA 的游戏，玩家可以在其中创建诸如他们自己模拟不同形式的约会和性行为，以了解后果模拟的、不健康或危及生命的环境，并确定艾滋病毒检测和预防服务。我们试图测试这个游戏的功效，并假设它的使用将导致艾滋病毒检测增加，并导致有感染风险的 AYA 中危险行为的减少艾滋病病毒。在这个二期应用中，我们的多学科团队招募了 AYA 进行迭代重点小组确认其他游戏增强功能的可接受性。随后我们进行了试点对 AYA（n=10）中的游戏干预进行现场测试，以确保可用性、可接受性并进行质量保证测试。我们现在计划进行一项随机对照试验确定干预措施对艾滋病毒检测的有效性。我们将招收300名性活跃的 HIV 阴性 AYA 并随机分配他们接受生活模拟游戏干预或包含艾滋病毒教育材料的应用程序。我们将比较自我报告两个研究组之间的艾滋病毒检测。成功完成这些目标将展示该产品如何促进基于证据的有效实施行为干预，以增加艾滋病毒检测并与青少年预防保健联系起来。这项核心技术的成功开发还可以进行修改以适用于其他领域医疗条件。