Interpersonal Emotion Regulation in Neurodegenerative Disease: Pathways to Caregiver Health

神经退行性疾病中的人际情绪调节：护理人员健康之路

• 批准号: 10834447
• 负责人: Casey Leigh Brown
• 金额: $ 7.51万
• 依托单位: GEORGETOWN UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2021
• 资助国家: 美国
• 起止时间: 2021-08-15 至 2025-05-31
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10834447
• 关键词: Acute; Affect; Aging; Alzheimer' s Disease; Area; Atrophic; Behavioral; Biological Markers; Blood; California; Caregivers; Caring; Cognitive; Collection; Conflict (Psychology); Development; Disease; Elderly; Emotional; Emotions; Empathy; Environment; Equation; Goals; Growth; Health; Health Psychology; Healthcare; Impairment; Individual; Lead; Link; Measurement; Memory; Mental Health; Mentorship; Modeling; Neurodegenerative Disorders; Outcome; Pathway interactions; Prevalence; Process; Psychology; Research; San Francisco; Sinus Arrhythmia; Spouse Caregiver; Techniques; Technology; Time; Training; Universities; Visual attention; adverse outcome; behavioral variant frontotemporal dementia; care recipients; career; caregiving; effective intervention; emotion regulation; emotional stimulus; experience; flexibility; functional disability; indexing; neural; physical conditioning; positive emotional state; respiratory; showing emotion; skills; stressor; theories; visual tracking

Project Summary/Abstract Neurodegenerative diseases lead to profound cognitive, emotional, and functional impairments that leave individuals dependent upon close relational partners who provide care. Although caregiving is a positive experience for many individuals, providing care for an individual who has socioemotional deficits due to neurodegenerative disease can lead to adverse consequences for spousal caregivers, including poor mental and physical health outcomes. However, little research examines the dyadic, interpersonal pathways through which care recipients' socioemotional deficits lead to health problems for their caregivers. The current research focuses on interpersonal emotion regulation – the extent to which a caregiver's negative emotion is downregulated and a caregiver's positive emotion is upregulated during conflict and an acute stressor with their care recipient – as a potential pathway linking care recipients' socioemotional deficits to their caregivers' health problems. The research will compare neurotypicals with individuals who have Alzheimer's Disease (AD) and behavioral variant frontotemporal dementia (bvFTD) to understand how these different disease types influence interpersonal emotion regulation (Aim 1). The research will delineate the neural, autonomic, and behavioral correlates of interpersonal emotion regulation (Aim 2), with an emphasis on disease related atrophy, autonomic, and behavioral factors theorized to subserve interpersonal emotion regulation, including vagal flexibility, visual attention to other's emotional expressions, and empathy. Finally, this research will examine whether poor interpersonal emotion regulation impacts caregiver health longitudinally (Aim 3). To support the candidate in conducting the proposed research, training is planned in: (a) measurement of changes in respiratory sinus arrhythmia as an index of vagal flexibility, (b) stationary and mobile eye-tracking technologies to capture visual attention to emotional stimuli, (c) health psychology and the collection of blood based health biomarkers, and (d) statistical growth modelling techniques in a structural equation modeling framework. The research environments within the Department of Psychology at the University of California, Berkeley, and the Memory and Aging Center at the University of California, San Francisco, will be ideal for the proposed training and research goals, as well as for developing the candidate's professional skills. Training will occur under the mentorship of renowned experts in each area of training, and will support the candidates career goal of transitioning into an independent research career. The proposed research will provide a more nuanced framework for understanding how socioemotional impairments due to neurodegenerative diseases affect caregivers' health over time, and advance our understanding of interpersonal emotion regulation and the dyadic processes that promote or hinder health in late life.

项目概要/摘要 神经退行性疾病会导致严重的认知、情感和功能障碍，从而导致 尽管照顾是积极的，但依赖提供照顾的亲密关系伙伴的个人。 许多人的经验，为因以下原因而出现社会情感缺陷的个人提供护理 神经退行性疾病可能会给配偶照顾者带来不良后果，包括精神不佳 然而，很少有研究探讨二元的人际途径。 目前的研究表明，被照顾者的社会情绪缺陷会导致其照顾者出现健康问题。 重点关注人际情绪调节——看护者负面情绪的程度 在冲突和急性压力源期间，护理人员的积极情绪会下调，而护理人员的积极情绪会上调 他们的被照顾者——作为将被照顾者的社会情感缺陷与其照顾者的社会情感缺陷联系起来的潜在途径 该研究将神经典型患者与阿尔茨海默病 (AD) 患者进行比较。 和行为变异型额颞叶痴呆 (bvFTD)，以了解这些不同的疾病类型如何 影响人际情绪调节（目标 1）。 人际情绪调节的行为相关性（目标 2），重点是疾病相关的萎缩， 从理论上讲，自主神经和行为因素有助于人际情绪调节，包括迷走神经 最后，本研究将考察灵活性、对他人情绪表达的视觉关注以及同理心。 人际情绪调节不良是否会纵向影响护理人员的健康（目标 3）。 在进行拟议研究的候选人中，计划在以下方面进行培训：(a) 衡量变化 呼吸性窦性心律失常作为迷走神经灵活性的指标，(b) 固定和移动眼动追踪技术 捕捉对情绪刺激的视觉注意，（c）健康心理学和基于血液的健康收集 生物标志物，以及（d）结构方程建模框架中的统计生长建模技术。 加州大学伯克利分校心理学系的研究环境 旧金山加利福尼亚大学记忆与衰老中心将是拟议培训的理想选择 和研究目标，以及发展候选人的专业技能的培训将在该框架下进行。 每个培训领域的知名专家的指导，并将支持候选人的职业目标 过渡到独立的研究生涯。拟议的研究将提供更细致的研究。 了解神经退行性疾病引起的社会情绪障碍如何影响的框架 随着时间的推移，护理人员的健康状况将得到改善，并增进我们对人际情绪调节和 促进或阻碍晚年健康的二元过程。

项目成果

Emotion regulation strategies and mental health in dementia caregivers: The moderating role of gender.

痴呆症护理人员的情绪调节策略和心理健康：性别的调节作用。

• DOI: 10.1159/000538398
• 发表时间: 2024
• 期刊: Dementia and geriatric cognitive disorders
• 影响因子: 2.4
• 作者: Bullard,BreannaM;Brown,CaseyL;Scheffer,JulianA;Toledo,AnnaB;Levenson,RobertW
• 通讯作者: Levenson,RobertW