Latinx Hazardous Drinkers with Clinical Anxiety: Effectiveness Trial of a Personalized Normative Feedback Intervention

患有临床焦虑的拉丁裔危险饮酒者：个性化规范反馈干预的有效性试验

基本信息

批准号：
10836087
负责人：
MICHAEL J. ZVOLENSKY
金额：
$ 4.32万
依托单位：
UNIVERSITY OF HOUSTON
依托单位国家：
美国
项目类别：
财政年份：
2021
资助国家：
美国
起止时间：
2021-09-20 至 2026-05-31
项目状态：
未结题

来源：
https://reporter.nih.gov/project-details/10836087
关键词：
Address Alcohol consumption Alcohols Anxiety Area Attitude Basic Science Behavior Therapy COVID-19 Caring Clinic Clinical Trials Design Community Health Computers Data Development Disease Disparity Effectiveness Expectancy Feedback Female Focus Groups Frequencies Goals Guidelines Happiness Health Health Services Accessibility Impairment Intention Intervention Knowledge Latinx Latinx population Literature Mediating Mediator Modeling Motivation National Institute on Alcohol Abuse and Alcoholism Outcome Participant Phase Population Populations at Risk Prevalence Public Health Randomized Randomized, Controlled Trials Reporting Research Research Project Grants Research Support Sampling Severities Standardization Strategic Planning Symptoms Testing Translating Treatment Cost Underserved Population United States United States National Institutes of Health Work acceptability and feasibility alcohol abuse therapy alcohol misuse alcohol misuse prevention alcohol related consequences alcohol use disorder anxiety management anxiety reduction anxiety symptoms biobehavior brief intervention clinical anxiety comorbidity compare effectiveness coping cost demographics design drinking effectiveness evaluation effectiveness testing effectiveness trial ethnic discrimination experience follow-up hazardous drinking health care settings health disparity health disparity populations health inequalities improved innovation intervention effect intervention refinement male novel optimism personalized normative feedback point of care psychoeducation psychoeducational public health priorities randomized, clinical trials recruit therapy design therapy development

项目摘要

Project Summary/Abstract Despite being one of the largest and fastest-growing demographics in the United States (US), Latinx persons experience striking health disparities, particularly in terms of hazardous drinking and co-occurring clinical anxiety. No interventions to date have targeted hazardous drinking in the context of clinical anxiety among Latinx persons. The current R01 proposal builds upon our past work by developing a brief, single-session, computer-based, personalized feedback intervention (PFI) designed to enhance knowledge regarding adverse anxiety-alcohol interrelations, increase motivation and intention to reduce hazardous drinking, and reduce positive attitudes and intentions regarding the use of alcohol for anxiety. Specifically, we propose to develop a low-cost, highly disseminatable, integrated PFI for Latinx hazardous drinkers with clinical anxiety (AA-PFI 1.0) that will be implemented and tested for effectiveness in community-based health clinics. Our approach will follow a staged model consistent with National Institutes of Health (NIH) guidelines for developing and standardizing behavioral interventions. Phase IA activities will involve collecting qualitative and quantitative feedback from three iterative focus groups (N = 21) to refine intervention content and evaluate treatment acceptability and feasibility. Phase IB activities will include a rigorous randomized clinical trial designed to compare the effectiveness of AA-PFI 2.0 to a control PFI (C-PFI) among a sample of 250 Latinx hazardous drinkers with clinical anxiety who receive care within community-based health clinics. This study represents an important and pivotal step in the larger landscape of translating basic research to more efficacious strategies for reducing hazardous drinking in underserved populations with biobehavioral comorbidities. The proposed research project supports the 2017-2021 strategic plan of the National Institute on Alcohol Abuse and Alcoholism (NIAAA) by advancing research in two of the key areas. First, the current proposal has the end goal of improving strategies to prevent alcohol misuse, alcohol use disorder, and alcohol-related consequences among an ‘at-risk’ population for these conditions (goal 3). Second, it enhances the public health impact of NIAAA-supported research by focusing on one of the fastest-growing and largest demographics in the US who demonstrate disparities in hazardous drinking (goal 5). The current application aligns with the goals of RFA- AA-21-001 by proposing to examine the effectiveness of a low cost, highly disseminatable, personalized, culturally adapted PFI for Latinx hazardous drinkers with clinical anxiety within community-based health clinics. Given the collective public health impact of concurrent anxiety and alcohol use, we believe the proposed study will yield findings that enhance scientific knowledge, advance our understanding of mechanisms in anxiety- alcohol use relations, and inform the development of novel treatments for hazardous drinkers with clinical anxiety that are adaptable and easily implemented across a variety of healthcare settings.

项目摘要/摘要尽管是美国（美国）最大，增长最快的人口统计学知识之一，但拉丁人还是经历了严重的健康差异，特别是在危险饮酒和同时发生的临床方面焦虑。迄今为止，在临床动画的背景下，迄今为止尚无干预措施。拉丁人。当前的R01提案通过开发简短的单节，基于计算机的个性化反馈干预（PFI），旨在增强有关逆境的知识焦虑酒精相互关系，增加动力和减少危险饮酒的意图，并减少关于使用酒精焦虑的积极吸引力和意图。具体来说，我们建议开发与临床动画的Latinx有害饮酒者的低成本，高度散布的集成PFI（AA-PFI 1.0）这将在基于社区的卫生诊所中实施和测试。我们的做法意愿遵循与国立卫生研究院（NIH）制定和发展指南一致的分阶段模型标准化行为干预措施。 IA阶段活动将涉及收集定性和定量来自三个迭代焦点小组（n = 21）的反馈，以完善干预内容和评估处理可接受性和可行性。 IB期活动将包括一个严格的随机临床试验将AA-PFI 2.0与对照PFI（C-PFI）的有效性进行比较250个拉丁文危险的样本中临床动画的饮酒者在社区健康诊所内接受护理。这项研究代表将基础研究转化为更有效策略的更大范围的重要和关键步骤为了减少患有生物行为合并症的人口不足的人群中的危险饮酒。提议研究项目支持美国国家酒精滥用研究所的2017 - 2021年战略计划酗酒（NIAAA）通过在两个关键领域进行研究。首先，当前的提议有最终目标改善防止滥用酒精的策略，酒精使用障碍和与酒精有关的后果在这些条件下的“处于危险中”的人群中（目标3）。其次，它增强了公共卫生的影响 NIAAA支持的研究通过着重于美国增长最快，最大的人口统计学之一展示危险饮酒中的分布（目标5）。当前的应用程序与RFA-的目标保持一致 AA-21-001提议检查低成本的有效性，高度差异，个性化，在基于社区的健康诊所内的临床动画的Latinx危险饮酒者的文化适应PFI。鉴于同时动画和饮酒的集体公共卫生影响，我们相信拟议的研究将产生增强科学知识的发现，促进我们对动画机制的理解 - 饮酒关系，并为临床的有害饮酒者开发新的治疗方法适应性且在各种医疗机构中很容易实施的焦虑。