San Diego StrokeNet Regional Coordinating Center

圣地亚哥 StrokeNet 区域协调中心

基本信息

批准号：
10837573
负责人：
BRETT C MEYER
金额：
$ 11.75万
依托单位：
UNIVERSITY OF CALIFORNIA, SAN DIEGO
依托单位国家：
美国
项目类别：
财政年份：
2023
资助国家：
美国
起止时间：
2023-08-01 至 2023-11-30
项目状态：
已结题

来源：
https://reporter.nih.gov/project-details/10837573
关键词：
Acute Address Advisory Committees Agreement Area Biological Markers Brain Caliber Caring Clinical Research Clinical Trials Collaborations Contracts Country Coupled Data Coordinating Center Dedications Development Devices Diffuse Discipline Educational process of instructing Eligibility Determination Enrollment Ensure Fellowship Funding Future Generations Grant Health Image Individual Industry Infrastructure Institutional Review Boards Knowledge Leadership Manuscripts Mentors Mission National Institute of Neurological Disorders and Stroke Nerve Regeneration Nervous System Outcome Patients Pediatrics Performance Population Procedures Process Productivity Public Health Publications Qualifying Recording of previous events Recovery Rehabilitation therapy Research Research Activity Research Personnel Research Training Resources Science Site Specialist Stroke Stroke prevention StrokeNet trials Techniques Time Training Training Programs United States United States National Institutes of Health Vocational Guidance Work acute stroke care delivery career career development clinical trial enrollment design experience improved investigator training lectures multidisciplinary nervous system disorder participant enrollment programs research and development research faculty stroke clinical trials stroke patient stroke trials success time interval tool trial enrollment working group

项目摘要

Project Summary The San Diego RCC is dedicated to the StrokeNet aims of delivering “Efficiency”, “Enrollments”, and “Training” by creating an optimized network, increasing trial enrollments, and enhancing career development. The results of this application will impact the stroke research field by enabling the discovery of acute, preventative, rehabilitation, recovery, neural regeneration, and imaging and biomarker techniques for stroke. UCSD is poised to continue to contribute to StrokeNet and support the NINDS’ mission to seek knowledge about the brain and nervous system to reduce the burden of neurological disease. Program: UCSD has participated in SPOTRIAS, StrokeNet, NIH, and industry trials in various areas of stroke with leadership and participation in over 50 stroke trials. The network has developed out of a local network, expanded over time and now includes 30 centers spanning three states. All sites have active Master Trial Agreements and Reliance Agreements in place. The UCSD Stroke Center has again engaged the support of the Dean, Chair, IRB, Contracting Office, CTRI, ED, EMS, and network investigators for this proposal. Research: The next cycle will focus on conducting trials and enrolling participants in the 30 RCC centers. The RCC-12 has a strong pool of potential network investigators who have set up their infrastructure and are awaiting to participate in a network trial. We also have the proven capacity to perform trials in pediatrics and rehab. UCSD has submitted trial ideas and as has others in development for proposal into the network. Leadership: UCSD has designated a PI (Meyer) and substitute PI (Hemmen), each with qualifications to serve effectively. UCSD serves on the Acute Stroke Working Group and the Neuro-Interventional Advisory Committee. In the multidisciplinary clinical trials’ team, experts from various disciplines are available to collaborate on trials in diverse arenas of stroke management. Trials particularly suited to areas of expertise of research faculty are assigned by the RCC-PI based on area of expertise. Career Enhancement: The Stroke Center has had full commitment to career guidance for trainees since 1987. The StrokeNet Career Enhancement Director (Hemmen) also serves as the fellow mentor for independent research activities. The training program focuses on research for the entire spectrum of stroke care. Didactic lectures and seminars are offered in diffuse topics. Administration: UCSD has had great success in producing high quality research, publications, and NIH trial enrollments due training on and following standard operating procedures (SOPs). The UCSD Stroke Center prioritizes StrokeNet and NIH funded trials as possible. Allocations grids mitigate against bias by guiding trial offerings fairly. Over the past 30 years, the UCSD Stroke Center has successfully performed trials in the full spectrum of stroke care, and is an ideal choice to continue leading a StrokeNet RCC.

项目概要圣地亚哥 RCC 致力于实现 StrokeNet 提供“效率”、“注册”和“培训”的目标通过创建优化的网络、增加试验注册人数和促进职业发展。该应用程序将通过发现急性、预防性、加州大学圣地亚哥分校已做好中风康复、恢复、神经再生、成像和生物标记技术的准备。继续为 StrokeNet 做出贡献并支持 NINDS 寻求有关大脑和大脑的知识的使命减轻神经系统疾病负担。项目：UCSD 参与了 SPOTRIAS、StrokeNet、NIH 以及中风各个领域的行业试验该网络是从本地网络发展而来的，并领导并参与了 50 多项中风试验。随着时间的推移不断扩大，现在包括跨越三个州的 30 个中心。所有站点都有活跃的主试验。已签订的协议和信赖协议加州大学圣地亚哥分校中风中心再次获得了以下机构的支持。院长、主席、IRB、合同办公室、CTRI、ED、EMS 以及本提案的网络调查员。研究：下一个周期将重点在 30 个 RCC 中心进行试验并招募参与者。 RCC-12 拥有强大的潜在网络调查人员库，他们已经建立了基础设施并正在等待我们还拥有在儿科和康复中心进行试验的能力。已提交试验想法，并与其他正在开发的提案一样进入网络。领导力：UCSD 已指定一名 PI (Meyer) 和替补 PI (Hemmen)，两人均具备任职资格加州大学圣地亚哥分校实际上是急性中风工作组和神经介入咨询委员会的成员。在多学科临床试验团队中，来自不同学科的专家可以合作进行试验在卒中管理的各个领域进行的试验特别适合研究人员的专业领域。由 RCC-PI 根据专业领域分配。职业提升：自 1987 年以来，中风中心一直致力于为学员提供职业指导。 StrokeNet 职业发展总监 (Hemmen) 还担任独立导师研究活动。培训计划侧重于整个中风护理领域的研究。讲座和研讨会的主题广泛。管理：加州大学圣地亚哥分校在高质量研究、出版物和 NIH 试验方面取得了巨大成功 UCSD 中风中心应接受并遵循标准操作程序 (SOP) 的培训。尽可能优先考虑 StrokeNet 和 NIH 资助的试验，分配网格通过指导试验来减少偏见。在过去的 30 年里，加州大学圣地亚哥分校中风中心已经成功地进行了全面的试验。中风护理领域，是继续领导 StrokeNet RCC 的理想选择。