San Diego StrokeNet Regional Coordinating Center

圣地亚哥 StrokeNet 区域协调中心

• 批准号: 10837573
• 负责人: BRETT C MEYER
• 金额: $ 11.75万
• 依托单位: UNIVERSITY OF CALIFORNIA, SAN DIEGO
• 依托单位国家: 美国
• 财政年份: 2023
• 资助国家: 美国
• 起止时间: 2023-08-01 至 2023-11-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10837573
• 关键词: Acute; Address; Advisory Committees; Agreement; Area; Biological Markers; Brain; Caliber; Caring; Clinical Research; Clinical Trials; Collaborations; Contracts; Country; Coupled; Data Coordinating Center; Dedications; Development; Devices; Diffuse; Discipline; Educational process of instructing; Eligibility Determination; Enrollment; Ensure; Fellowship; Funding; Future; Generations; Grant; Health; Image; Individual; Industry; Infrastructure; Institutional Review Boards; Knowledge; Leadership; Manuscripts; Mentors; Mission; National Institute of Neurological Disorders and Stroke; Nerve Regeneration; Nervous System; Outcome; Patients; Pediatrics; Performance; Population; Procedures; Process; Productivity; Public Health; Publications; Qualifying; Recording of previous events; Recovery; Rehabilitation therapy; Research; Research Activity; Research Personnel; Research Training; Resources; Science; Site; Specialist; Stroke; Stroke prevention; StrokeNet trials; Techniques; Time; Training; Training Programs; United States; United States National Institutes of Health; Vocational Guidance; Work; acute stroke; care delivery; career; career development; clinical trial enrollment; design; experience; improved; investigator training; lectures; multidisciplinary; nervous system disorder; participant enrollment; programs; research and development; research faculty; stroke clinical trials; stroke patient; stroke trials; success; time interval; tool; trial enrollment; working group

Project Summary The San Diego RCC is dedicated to the StrokeNet aims of delivering “Efficiency”, “Enrollments”, and “Training” by creating an optimized network, increasing trial enrollments, and enhancing career development. The results of this application will impact the stroke research field by enabling the discovery of acute, preventative, rehabilitation, recovery, neural regeneration, and imaging and biomarker techniques for stroke. UCSD is poised to continue to contribute to StrokeNet and support the NINDS’ mission to seek knowledge about the brain and nervous system to reduce the burden of neurological disease. Program: UCSD has participated in SPOTRIAS, StrokeNet, NIH, and industry trials in various areas of stroke with leadership and participation in over 50 stroke trials. The network has developed out of a local network, expanded over time and now includes 30 centers spanning three states. All sites have active Master Trial Agreements and Reliance Agreements in place. The UCSD Stroke Center has again engaged the support of the Dean, Chair, IRB, Contracting Office, CTRI, ED, EMS, and network investigators for this proposal. Research: The next cycle will focus on conducting trials and enrolling participants in the 30 RCC centers. The RCC-12 has a strong pool of potential network investigators who have set up their infrastructure and are awaiting to participate in a network trial. We also have the proven capacity to perform trials in pediatrics and rehab. UCSD has submitted trial ideas and as has others in development for proposal into the network. Leadership: UCSD has designated a PI (Meyer) and substitute PI (Hemmen), each with qualifications to serve effectively. UCSD serves on the Acute Stroke Working Group and the Neuro-Interventional Advisory Committee. In the multidisciplinary clinical trials’ team, experts from various disciplines are available to collaborate on trials in diverse arenas of stroke management. Trials particularly suited to areas of expertise of research faculty are assigned by the RCC-PI based on area of expertise. Career Enhancement: The Stroke Center has had full commitment to career guidance for trainees since 1987. The StrokeNet Career Enhancement Director (Hemmen) also serves as the fellow mentor for independent research activities. The training program focuses on research for the entire spectrum of stroke care. Didactic lectures and seminars are offered in diffuse topics. Administration: UCSD has had great success in producing high quality research, publications, and NIH trial enrollments due training on and following standard operating procedures (SOPs). The UCSD Stroke Center prioritizes StrokeNet and NIH funded trials as possible. Allocations grids mitigate against bias by guiding trial offerings fairly. Over the past 30 years, the UCSD Stroke Center has successfully performed trials in the full spectrum of stroke care, and is an ideal choice to continue leading a StrokeNet RCC.

项目摘要 圣地亚哥RCC致力于提供“效率”，“入学率”和“培训”的目标。 通过创建优化的网络，增加试用入学率并增强职业发展。结果 该应用程序将通过发现急性，预防性， 中风的康复，恢复，神经变成以及成像和生物标志物技术。 UCSD中毒 继续为拼写物做出贡献，并支持Ninds的使命，以寻求有关大脑的知识和 神经系统减少神经系统疾病的燃烧。 计划：UCSD在中风的各个领域参加了点播，Strokenet，NIH和行业试验 领导和参与50多个中风试验。该网络已经从本地网络开发， 随着时间的推移扩展，现在包括30个跨越三个州的中心。所有站点均具有主动审判 协议和依赖协议已到位。 UCSD中心中心再次与 该提案的Dean，IRB主席，IRB，CTRI，ED，EMS和网络调查人员的委托办公室。 研究：下一个周期将着重于进行试验并招募30个RCC中心的参与者。这 RCC-12有大量的潜在网络调查员，他们已经建立了基础架构并正在等待 参加网络试验。我们还具有在儿科和康复中进行考验的可靠能力。 UCSD 已经提交了审判思想，以及其他正在开发的提案中的想法。 领导力：UCSD指定了PI（Meyer）和替代PI（Hemmen），每个PI都有资格服务 UCSD在急性中风工作组和神经间歇性咨询委员会中任职。 在多学科临床试验团队中，来自各个学科的专家可以合作进行试验 在中风管理的潜水领域。特别适合研究教师专业领域的试验是 由RCC-PI根据专业知识而分配。 职业增强：自1987年以来，中风中心一直致力于培训的职业指导。 Strokenet职业增强总监（HEMMEN）也是独立的精神 研究活动。该培训计划着重于整个中风护理的研究。教学 讲座和半手以漫射主题提供。 管理：UCSD在生产高质量研究，出版物和NIH试验方面取得了巨大成功 由于培训和遵循标准操作程序（SOP）的培训引起的注册。 UCSD卒中中心 优先考虑Strokenet和NIH资助的试验。分配网格通过指导试验来减轻偏见 公平供电。在过去的30年中，UCSD中风中心已成功进行了全面试验 中风护理的范围，是继续领导Strokenet RCC的理想选择。