Administrative Core

行政核心

基本信息

批准号：
10845856
负责人：
VINEET D MENACHERY
金额：
$ 257.77万
依托单位：
UNIVERSITY OF TEXAS MED BR GALVESTON
依托单位国家：
美国
项目类别：
财政年份：
2022
资助国家：
美国
起止时间：
2022-05-16 至 2025-04-30
项目状态：
未结题

来源：
https://reporter.nih.gov/project-details/10845856
关键词：
Antiviral Agents Award Clinic Clinical Communication Communities Coronavirus Decision Making Development Development Plans Educational workshop Ensure Faculty Flavivirus Goals Health Henipavirus Hybrids Industry Intellectual Property Investigational Drugs Leadership Mentors Modeling Peer Review Pharmaceutical Preparations Postdoctoral Fellow Prevention Program Research Project Grants Qualifying Research Research Personnel Research Project Grants Resource Sharing Resources Science Structure Training Translations United States National Institutes of Health Viral career career development clinical candidate data sharing design drug candidate drug development drug discovery experience functional group industry partner innovation meetings multidisciplinary new technology new therapeutic target next generation organizational structure pandemic disease pandemic pathogen pandemic potential pandemic preparedness preclinical development preclinical study prevent pandemics programs success virology

项目摘要

ADMINISTRATIVE CORE - ABSTRACT The “UTMB-Novartis Alliance for Pandemic Preparedness (UNAPP)” combines UTMB’s excellence in virology & BSL4/3 facility with Novartis’ power in drug discovery & development to deliver pandemic antivirals. The Administrative Core provides the leadership and programmatic coordination required to fully realize the impact of this unique academic-industry partnership and meet the goals of the Antiviral Drug Discovery Centers for Pathogens of Pandemics Concern. We will accomplish this through the following four aims: i. implement an integrated organizational governance and programmatic structure that will promote a team science approach to antiviral drug discovery for pandemic prevention against Coronaviruses, Flaviviruses, and Henipaviruses; ii. provide integrated decision making in scientific, operational, financial, intellectual property protection and communication through cohesive and collaborative governance; iii. implement a Developmental Research Project program that will expand the center's scope and range of research while encouraging outside investigators to develop novel technology and innovative research ideas in antiviral drug discovery; and iv. implement a Mentored Project program designed to increase the availability of qualified early career researchers in antiviral discovery research by providing career development and mentored research to further their professional advancement.

行政核心 - 摘要 “UTMB-诺华流行病防范联盟 (UNAPP)”结合了 UTMB 在病毒学方面的卓越优势 & BSL4/3 设施拥有诺华在药物发现和开发方面的实力，可提供大流行性抗病毒药物。行政核心提供充分实现影响所需的领导和计划协调这种独特的学术与工业合作伙伴关系，并实现抗病毒药物发现中心的目标我们将通过以下四个目标来实现这一目标：综合的组织治理和计划结构将促进团队科学方法用于预防冠状病毒、黄病毒和亨尼帕病毒大流行的抗病毒药物的发现；提供科学、运营、财务、知识产权保护等方面的综合决策通过凝聚力和协作治理进行沟通； iii．项目计划将扩大中心的研究范围和范围，同时鼓励外部研究研究人员在抗病毒药物发现方面开发新技术和创新研究理念；实施指导项目计划，旨在增加合格的早期职业研究人员的可用性通过提供职业发展和指导研究来进一步促进抗病毒发现研究专业进步。