Mentored Training in Molecular Epidemiology of Chronic Kidney Disease in Diverse Populations

不同人群慢性肾脏病分子流行病学指导培训

基本信息

批准号：
10799234
负责人：
Nora Franceschini
金额：
$ 6.92万
依托单位：
UNIV OF NORTH CAROLINA CHAPEL HILL
依托单位国家：
美国
项目类别：
财政年份：
2023
资助国家：
美国
起止时间：
2023-09-15 至 2028-07-31
项目状态：
未结题

来源：
https://reporter.nih.gov/project-details/10799234
关键词：
Adult Affect American Heart Association American Indians Area Atherosclerosis Risk in Communities Award Black Populations Cardiovascular Diseases Cause of Death Cessation of life Chronic Kidney Failure Cohort Studies Data Dedications Developing Countries Disease Diverse Workforce Education Educational process of instructing Enrollment Epidemiologist Epidemiology Epigenetic Process Etiology Faculty Funding Genetic Genetic Research Goals Grant Heart Hispanic Community Health Study/Study of Latinos Hispanic Populations Individual International Intervention Kidney Latino Population Leadership Learning Mentors Mentorship Methods Molecular Molecular Epidemiology Nephrology North Carolina Paper Population Population Heterogeneity Positioning Attribute Postdoctoral Fellow Prevention Principal Investigator Proteomics Public Health Publications Research Research Personnel Research Project Grants Research Support Risk Risk Factors Science Scientist Societies Source Therapeutic Time Training Trans-Omics for Precision Medicine Underrepresented Populations United States National Institutes of Health Universities Women&apos s Health Work Writing agricultural community base burden of illness cardiovascular disorder epidemiology career design disability epidemiology study experience genetic epidemiology genetic variant graduate school graduate student improved meetings member metabolomics molecular marker multidisciplinary next generation pre-doctoral premature programs recruit skills tool transcriptome

项目摘要

ABSTRACT Chronic kidney disease affects one in seven U.S. adults and is a leading cause of death and disability. Chronic kidney disease has a substantial impact on U.S. diverse populations, including Blacks, Hispanics/Latinos and American Indians. Research on the epidemiology and molecular risk factors contributing to chronic kidney disease in diverse populations is much needed to guide public health prevention and interventions, and to develop therapeutic tools for clinicians to effectively treat the disease. This K26 application will support protected time for Nora Franceschini, MD MPH, to mentor junior investigators from underrepresented groups in science on molecular epidemiology research of chronic kidney disease in diverse populations. Dr. Franceschini is a nephrologist and an epidemiologist with a 20-year experience conducting multidisciplinary studies in chronic kidney disease and mentoring graduate students and early-stage investigators, including those from underrepresented groups. Dr. Franceschini has developed a strong National Institutes of Health supported research program on chronic kidney disease at the University of North Carolina focused on diverse populations. This research program offers multiple opportunities for trainees to learn rigorous research skills in state-of-art approaches for research in the epidemiology, molecular epidemiology and biomarkers of chronic kidney disease. Proposed activities and enhanced mentoring skills support the goals to increase high-quality mentoring for the next generation of scientists (including URGs) in chronic kidney disease research within her research program.

抽象的慢性肾病影响着七分之一的美国成年人，是导致死亡和残疾的主要原因。慢性的肾脏疾病对美国不同人群有重大影响，包括黑人、西班牙裔/拉丁裔和美国印第安人。慢性肾脏病的流行病学及分子危险因素研究非常需要了解不同人群的疾病情况来指导公共卫生预防和干预，并为临床医生开发有效治疗疾病的治疗工具。此 K26 应用程序将支持诺拉·弗朗西斯基尼（Nora Franceschini），医学博士，公共卫生硕士，有受保护的时间指导来自代表性不足群体的初级调查员不同人群慢性肾脏病的分子流行病学研究科学。弗朗西斯基尼博士是一位肾病学家和流行病学家，在以下领域开展多学科研究拥有 20 年经验慢性肾脏病并指导研究生和早期研究人员，包括来自代表性不足的群体。 Franceschini 博士开发了美国国立卫生研究院的强大支持北卡罗来纳大学慢性肾脏病研究项目侧重于多种人口。该研究计划为学员提供了多种学习严格研究技能的机会慢性病流行病学、分子流行病学和生物标志物研究的最先进方法肾脏疾病。拟议的活动和增强的指导技能支持提高高质量的目标指导下一代科学家（包括 URG）进行慢性肾病研究研究计划。