Administrative Core

行政核心

基本信息

批准号：
10704046
负责人：
JEFFREY R. CURTIS
金额：
$ 26.64万
依托单位：
UNIVERSITY OF ALABAMA AT BIRMINGHAM
依托单位国家：
美国
项目类别：
财政年份：
2020
资助国家：
美国
起止时间：
2020-09-15 至 2024-07-31
项目状态：
已结题

来源：
https://reporter.nih.gov/project-details/10704046
关键词：
Address Advisory Committees Alabama Area Arthritis Autoimmunity Bioinformatics Biometry Biosensor Center for Translational Science Activities Clinical Clinical Research Clinical Sciences Collection Communities Core Facility Data Data Sources Dermatology Development Devices Disease Doctor of Philosophy Education Electronic Health Record Ensure Environment Epidemiology Evaluation Evolution Faculty Fostering Funding Future Goals Gout Grant Health Technology Health care facility Healthcare Hyperuricemia Individual Informatics Institution Investigation Knowledge Leadership Machine Learning Methodology Methods Mission Musculoskeletal Musculoskeletal Diseases National Center for Advancing Translational Sciences National Institute of Arthritis, and Musculoskeletal, and Skin Diseases Natural Language Processing Orthopedics Outcomes Research Patient Care Patient Outcomes Assessments Patients Pharmaceutical Economics Pharmacoepidemiology Policy Maker Registries Research Research Personnel Research Project Grants Resources Rheumatism Rheumatology Science Services Technology Translational Research Universities Visualization Work base bone catalyst clinical center comorbidity computer science computerized data processing data visualization deep learning design digital health digital imaging early-career faculty effectiveness research experience health plan implementation science improved innovation knowledge translation member mobile application mobile computing new technology novel operation programs research study skills skin disorder smartphone application statistics tool wearable device wearable sensor technology

项目摘要

PROJECT SUMMARY The University of Alabama at Birmingham's (UAB) Building and InnovatinG: Digital heAlth Technology and Analytics (BIGDATA) Core Center will serve as a catalyst for the design and implementation of rigorous, high- impact clinical research studies advance musculoskeletal, arthritis and skin disease research inside and outside the confines of traditional health care facilities, using data captured by mobile technology including Smartphone Apps and wearable biosensor devices. Oversight of the Center will be provided by the Administrative Core directed by Jeffrey Curtis, MD, MS, MPH, Associate Director Huifeng Yun, PhD, and key faculty S. Louis Bridges, Jr., MD, PhD and, Kenneth Saag, MD, MSc. The central purpose of the Administrative Core is to oversee all operations of the Center and facilitate BIGDATA's mission to improve the design, collection and analysis of real-world (e.g. electronic health record, registry, health plan, biosensor), and 'omic' data as applied to rheumatologic, musculoskeletal, and skin disease research using both traditional and novel data sources (e.g. Smartphone Apps, biosensors/wearables, digital images) and methods (e.g. data visualization; natural language processing data; machine learning and deep learning analytics) via the following specific aims: (1) Set the priorities and the overall strategic agenda to facilitate rheumatologic, musculoskeletal, and skin disease research; (2) Coordinate Core facilities, supporting a vigorous intellectual and scholarly research environment; (3) Facilitate the continued evolution of the highly successful Methodologic Core and its expansion to incorporate novel technologies embedded in the Data Capture & Integration Core (DCI) to develop new services and innovative research projects using state-of-the-art tools from rheumatology, informatics, statistics, epidemiology, implementation science, and outcomes research at UAB and Auburn University; (4) Oversee the continuation of the outstanding educational enrichment programs designed to bolster the knowledge and skills of the user base, leading to higher quality clinical research; (5) Foster the development and provide oversight and management of Pilot and Feasibility projects; (6) Coordinate interactions with the Executive & Advisory Committees, and existing UAB entities such as the NCATS-funded Center for Clinical and Translational Science, UAB Informatics Institute, NIAMS-funded Investigations in Gout, Hyperuricemia, and Comorbidities P50 Center of Research Translation; the Comprehensive Arthritis, Musculoskeletal, Bone, and Autoimmunity Center; Center for Outcomes and Effectiveness Research and Education, and the UAB Pharmacoepidemiology & pharmacoEconomics unit; (7) Serve as the evaluation touchstone to: a) ensure continuous quality improvement in leadership, engagement and the quality of services and resources provided by BIGDATA to the User Base, and b) quantify BIGDATA's impact on the research community.

项目概要阿拉巴马大学伯明翰分校 (UAB) 的建设和创新：数字医疗技术和分析（大数据）核心中心将充当严格、高水平的设计和实施的催化剂。影响临床研究推进肌肉骨骼、关节炎和皮肤病研究在传统医疗保健设施的范围之外，使用移动技术捕获的数据，包括智能手机应用程序和可穿戴生物传感器设备。该中心的监督将由行政核心由 Jeffrey Curtis（医学博士、硕士、公共卫生硕士）指导，副主任云慧峰（博士）和关键教员 S. Louis Bridges, Jr.（医学博士、哲学博士）和 Kenneth Saag（医学博士、理学硕士）。该组织的中心目的是行政核心是监督中心的所有运营并促进 BIGDATA 的使命，以改善现实世界的设计、收集和分析（例如电子健康记录、登记、健康计划、生物传感器），以及 “组学”数据应用于风湿病、肌肉骨骼和皮肤病研究，使用传统和新颖的数据源（例如智能手机应用程序、生物传感器/可穿戴设备、数字图像）和方法（例如数据可视化；自然语言处理数据；机器学习和深度学习分析）通过以下具体目标： (1) 制定优先事项和总体战略议程，以促进风湿病、肌肉骨骼和皮肤疾病研究；（二）协调核心设施，支撑活力智力和学术研究环境；（3）促进高度成功的企业的持续发展 Methodologic Core 及其扩展，整合了数据采集和数据采集中嵌入的新技术集成核心 (DCI) 使用最先进的工具开发新服务和创新研究项目来自风湿病学、信息学、统计学、流行病学、实施科学和结果研究 UAB 和奥本大学；（四）监督优秀教育充实计划的延续旨在增强用户群的知识和技能，从而实现更高质量的临床研究； (5) 促进试点和可行性项目的开发并提供监督和管理； (6) 协调与执行和咨询委员会以及现有 UAB 实体（例如 NCATS 资助的临床和转化科学中心、UAB 信息学研究所、NIAMS 资助痛风、高尿酸血症和合并症的调查 P50 研究翻译中心；这综合关节炎、肌肉骨骼、骨骼和自身免疫中心；结果中心和有效性研究和教育，以及 UAB 药物流行病学和药物经济学部门； (7) 作为评估试金石： a) 确保领导力、参与度方面的质量持续改进以及 BIGDATA 向用户群提供的服务和资源的质量，以及 b) 量化 BIGDATA 的对研究界的影响。