MD Anderson Science Park Summer Program in Cancer Research SPCR

MD 安德森科学园癌症研究 SPCR 暑期项目

• 批准号: 10685275
• 负责人: MARK T. BEDFORD
• 金额: $ 19.2万
• 依托单位: UNIVERSITY OF TX MD ANDERSON CAN CTR
• 依托单位国家: 美国
• 财政年份: 2014
• 资助国家: 美国
• 起止时间: 2014-08-11 至 2024-08-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10685275
• 关键词: Academia; Address; Area; Basic Science; Biotechnology; Cancer Biology; Cancer Center; Cancer Etiology; Career Choice; Cell Death; Cell Survival; Cells; Clinical; Clinical Oncology; Communication; Complement; Computational Biology; Country; DNA Repair; Data; Dedications; Diagnosis; Discipline; Educational process of instructing; Environment; Epigenetic Process; Evaluation; Exposure to; Faculty; Genes; Geography; Goals; Government Agencies; Graduate Education; Grant; Health; Healthcare; Home; Hospitals; Immunology; Immunotherapy; Individual; Institution; International; Knowledge; Laboratories; Laboratory Research; Learning; Malignant Neoplasms; Medicine; Mentors; Methods; Mind; Mission; Molecular Carcinogenesis; Mutagenesis; Neoplasm Metastasis; Oncology; Participant; Postdoctoral Fellow; Preparation; Prevention; Procedures; Qualifying; Research; Research Methodology; Research Personnel; Research Project Grants; Science; Scientist; Series; Students; Supervision; Talents; Techniques; Technology; Texas; Training; Training and Education; Translational Research; University of Texas M D Anderson Cancer Center; Virus; Work; academic program; angiogenesis; anticancer research; austin; cancer genetics; cancer genomics; cancer initiation; cancer therapy; career; career development; comparative; design; experience; faculty mentor; field trip; graduate school; graduate student; hands on research; interest; laboratory experience; lectures; member; model organism; next generation; nonhuman primate; oral communication; posters; programs; research facility; skills; stem cells; student participation; summer internship; summer program; summer research; summer student; symposium; targeted treatment; undergraduate student; videoconference; viral carcinogenesis

PROJECT SUMMARY The goal of the Summer Program in Cancer Research (SPCR) is to provide talented undergraduate students with a research project-based laboratory experience and exposure to different science and health disciplines working to address the causes, diagnosis, prevention, and treatment of cancer. The Program objective is to promote careers in cancer research and clinical oncology, which is in line with the NCI mission to attract and train the best minds to become the next generation of cancer researchers. This goal will be accomplished through a formalized 10-week program during which participants will work on an individualized research project under the supervision of a faculty mentor. The MD Anderson Science Park campus in Smithville, Texas, provides a unique environment for young scientists to engage in cutting-edge research using state-of-the-art technologies while working in a park-like setting. Participating faculty members are not only committed educators but also internationally recognized experts in the fields of cancer genetics and genomics, epigenetics, DNA repair and mutagenesis, stem cells, immunology, and mechanisms of cell death and survival. Students will also gain an appreciation for other areas of cancer biology, such as viral carcinogenesis, angiogenesis, and metastasis, through a Program lecture series complemented by additional lectures video conferenced from Houston designed for all summer students at MD Anderson. An appreciation for the wide variety of research being performed at MD Anderson will also be gained through field trip experiences to the MD Anderson main campus and hospital in Houston and the Keeling Center for Comparative Medicine. Students will be exposed to the variety of career options available to individuals interested in cancer research through career development lectures and a Careers in Science Panel Discussion. Students will also learn how to organize a scientific presentation, including background information, hypothesis, methods, results, and conclusions, and will hone their oral communication skills in preparation for a culminating Scientific Symposium, where students present their research projects to departmental faculty, trainees, and staff. Past programmatic evaluations demonstrate that the SPCR is an important contributor to the career development of participating students and influenced their decision and ability to pursue graduate or other training leading to careers in cancer-related research and medicine.

项目摘要 夏季癌症研究计划（SPCR）的目标是为才华横溢的本科生提供 凭借研究基于项目的实验室经验并接触不同的科学和健康学科 致力于解决癌症的原因，诊断，预防和治疗。程序的目标是 促进癌症研究和临床肿瘤学的职业，这与NCI吸引和吸引和 训练最好的思想，成为下一代癌症研究人员。这个目标将通过 一个正式的10周计划，在此期间，参与者将在一个个性化的研究项目中工作 教师导师的监督。德克萨斯州史密斯维尔的MD安德森科学公园校园提供了一个 年轻科学家使用最先进的技术进行尖端研究的独特环境 在公园般的环境中工作。参加教师不仅是忠实的教育者，而且是 国际公认的癌症遗传学和基因组学领域，表观遗传学，DNA修复和 诱变，干细胞，免疫学和细胞死亡和生存机制。学生还将获得 对其他癌症生物学领域的欣赏，例如病毒癌变，血管生成和转移， 通过节目讲座系列，并由休斯敦授予的其他演讲视频。 专为MD Anderson的所有夏季学生设计。对各种各样的研究的赞赏 在MD安德森（MD Anderson）表演也将通过到MD Anderson主校园的实地考察经验获得 休斯顿的医院和龙骨比较医学中心。学生将接触到 通过职业发展感兴趣的个人可以使用各种职业选择 科学小组讨论中的讲座和职业。学生还将学习如何组织科学 演示文稿，包括背景信息，假设，方法，结果和结论，并将磨练 他们的口头沟通技巧，以准备高潮的科学研讨会，学生在这里 他们的研究项目向部门的教职员工，学员和员工。过去的程序评估证明了 SPCR是参与学生职业发展的重要贡献者，并影响了 他们的决策和能力从事研究生或其他培训，导致与癌症相关研究的职业和 药品。

项目成果

Age-Dependent Alterations in Meiotic Recombination Cause Chromosome Segregation Errors in Spermatocytes.

• DOI: 10.1016/j.cell.2017.08.042
• 发表时间: 2017-10-19
• 期刊: Cell
• 影响因子: 64.5
• 作者: Zelazowski MJ;Sandoval M;Paniker L;Hamilton HM;Han J;Gribbell MA;Kang R;Cole F
• 通讯作者: Cole F

Differential ETS1 binding to T:G mismatches within a CpG dinucleotide contributes to C-to-T somatic mutation rate of the IDH2 hotspot at codon Arg140.

• DOI: 10.1016/j.dnarep.2022.103306
• 发表时间: 2022-05
• 期刊: DNA REPAIR
• 影响因子: 3.8
• 作者: Yang, Jie;Gupta, Esha;Horton, John R.;Blumenthal, Robert M.;Zhang, Xing;Cheng, Xiaodong
• 通讯作者: Cheng, Xiaodong