Enhancing Blood Donation at Schools and Beyond: An Implementation Science Study

加强学校及其他场所的献血：一项实施科学研究

• 批准号: 10683391
• 负责人: MINA CHRISTINE HOSSEINIPOUR
• 金额: $ 57.91万
• 依托单位: MALAWI BLOOD TRANSFUSION SERVICE
• 依托单位国家: 美国
• 财政年份: 2020
• 资助国家: 美国
• 起止时间: 2020-07-01 至 2026-06-30
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10683391
• 关键词: Age; Anemia; Area; Behavioral Sciences; Blood; Blood Banks; Blood Donations; Blood Transfusion; Cessation of life; Characteristics; Clinical Trials; Collection; Communication; Communities; Consolidated Framework for Implementation Research; Country; Data; Data Reporting; Databases; Discipline of obstetrics; Eligibility Determination; Ensure; Epidemiologic Monitoring; Epidemiology; Evaluation; Event; Familiarity; Focus Groups; Geographic Locations; Geography; Gifts; Goals; Grant; HIV; Health; Hemorrhage; High School Student; Hospitals; Hotlines; Hybrids; Implementation readiness; Infant; Infection; Interdisciplinary Study; Intervention; Interview; Malaria; Malawi; Maternal Mortality; Measures; Mission; Modeling; Modification; Monitor; Motivation; Performance; Phase; Policies; Qualitative Evaluations; Qualitative Methods; Qualitative Research; Randomized; Research; Research Personnel; Risk; Role; Schools; Secondary Schools; Services; Site; Students; System; Telephone; Text Messaging; Time; Transfusion; Update; Vascular blood supply; Youth; community engagement; cost effectiveness; data quality; design; effectiveness evaluation; effectiveness outcome; expectation; experimental study; health data; implementation science; implementation strategy; improved; incentive program; information gathering; meetings; mortality; preference; prevent; preventable death; programs; randomized, clinical trials; recruit; research study; retention rate; service programs; social media; transfusion medicine; transmission process; trial design; uptake; volunteer

Enhancing blood Donation at Schools and Beyond: An implementation Science study Project Summary Over the past decade, Malawi has made substantial progress in improving critical health measures including reducing infant, under-5 years mortality, maternal mortality rate, and HIV associated deaths. Despite this progress, preventable deaths from malaria-associated anemia and obstetric hemorrhage still occur due to blood shortage in the country. Over the last 15 years, the Malawi Blood Transfusion Services (MBTS) has dramatically increased its capacity for blood collection and distribution, but the goal of 100% collection by MBTS has not been achieved and there remains a 27% deficit of the nation’s need. Current MBTS program data suggest secondary student donations programs yield the highest uptake of blood donations but many of these student donors are not retained long term, particularly after graduation. As regular donors provide the lowest risk of transmitted transfusion infections, identifying effective strategies for increasing regular donors is critical in ensuring sustainable supply of safe blood. The application’s emphasis is on identifying sustainable and efficient donor recruitment and retention strategies that would increase safe blood donations in Malawi, taking advantage of the apparent enthusiasm of youth to donate blood and their relatively low risk of transmitted transfusion infections. Specifically, three aims will be implemented: Phase 1 (UG3), Aim 1: Conduct spatial, epidemiological and Hemovigilance analysis of existing MBTS and Ministry of Health (MOH) data from current blood collections systems to identify optimal functioning districts for replication, data quality improvement and potential inclusion for implementation science trial; Aim 2: Conduct evaluation of facilitators and barriers to blood collection and repeat donations according to high and low performing districts/programs/schools in order to inform and refine implementation science strategy; and Phase 2 (UH3), Aim 3: Determine the effectiveness of an enhanced Malawian-tailored school-based donation club program to promote first time donation and engage donor retention post-secondary school. Informed by a Consolidated Framework for Implementation Research, we expect this proposed trial will yield culturally sensitive, age appropriate incentive programs, donor messaging and communication strategies to maximize enthusiasm for donation. The consortium brings together a multi-disciplinary research team with expertise in blood transfusion medicine, epidemiology, behavioral science, implementation science and familiarity with the Malawian culture and context to achieve the objectives. Implementation science capacity building for young Malawian investigators is embedded within the grant’s activities to ensure continued research in blood transfusion medicine long term.

增强学校及以后的献血：实施科学研究 项目摘要 在过去的十年中，马拉维在改善关键健康方面取得了重大进展 措施包括减少婴儿，5岁以下的死亡率，孕产妇死亡率和艾滋病毒 相关死亡。尽管取得了这种进展，但可预防的疟疾贫血死亡 由于该国的血液短缺，产科出血仍然发生。在过去的15年中， 马拉维输血服务（MBT）显着提高了其血液的能力 收集和分发，但MBT的100％收集目标尚未实现，并且 对国家需求仍然存在27％的赤字。当前的MBTS程序数据建议次要 学生捐赠计划产生的血液捐赠最高，但其中许多学生 捐助者没有长期保留，尤其是毕业后。作为普通捐助者提供的 传播传输感染的最低风险，确定增加的有效策略 常规捐助者对于确保可持续的安全血液供应至关重要。 该申请的重点是确定可持续和有效的捐助者招聘以及 保留策略将利用马拉维的安全献血，利用 年轻人对献血及其相对低风险的热情显然 输血感染。具体来说，将实施三个目标：第1阶段（UG3），目标1： 进行现有MBT和事工的空间，流行病学和血液升温分析 来自当前血液收集系统的健康（MOH）数据，以识别最佳功能 复制，数据质量改进和实施的潜在包含区 科学试验；目标2：进行促进者和收集血液障碍的评估和 根据高表现区/计划/学校重复捐款 告知并完善实施科学战略；和第2阶段（UH3），目标3：确定 增强了马拉维制定学校捐赠俱乐部计划的有效性 促进第一次捐款并参与捐助后院登上学院。由a告知 合并实施研究框架，我们预计该提议的试验将产生 对文化敏感，适当的激励计划，捐助者消息传递和沟通 最大化捐赠热情的策略。 该财团汇集了一个具有血液专业知识的多学科研究团队 输血医学，流行病学，行为科学，实施科学和熟悉 有了马拉维文化和背景，以实现目标。实施科学能力 为年轻的马拉维调查人员建造赠款的活动，以确保 长期持续研究输血医学。