2023 Phagocytes Gordon Research Conference and Gordon Research Seminar

2023吞噬细胞戈登研究大会暨戈登研究研讨会

基本信息

批准号：
10683594
负责人：
Sergio Daniel Catz
金额：
$ 1.1万
依托单位：
GORDON RESEARCH CONFERENCES
依托单位国家：
美国
项目类别：
财政年份：
2023
资助国家：
美国
起止时间：
2023-03-06 至 2024-02-29
项目状态：
已结题

来源：
https://reporter.nih.gov/project-details/10683594
关键词：
Adaptive Immune System Address Advocate Alzheimer&apos s Disease Amoeba genus Area Atherosclerosis Atmosphere Autoimmune Diseases Autoimmunity Autophagocytosis Biochemistry Biology Biomedical Engineering Brain COVID-19 Cardiovascular Diseases Cell Death Cells Cellular biology Clinical Clinical Medicine Collaborations Communicable Diseases Communication Communities Dendritic Cells Development Diabetes Mellitus Disabled Persons Disease Engineering Ensure Environment Equity Ethnic Population Exclusion Faculty Feedback Female Financial Support Fostering Future Genetic Genomics Goals Growth HIV-associated neurocognitive disorder Health Homeostasis Host Defense Hour Human Image Immune system Immunity Immunology Individual Infection Inflammation Inflammatory Bowel Diseases Innate Immune System International Knowledge Lead Learning Location Longevity Lupus Macrophage Malignant Neoplasms Mentors Mentorship Microbiology Microglia Mission Molecular Molecular Genetics Multiple Sclerosis National Institute of Allergy and Infectious Disease Neurologic New Hampshire Pathologic Pathologic Processes Pathology Phagocytes Phagocytosis Pharmacology Play Postdoctoral Fellow Research Research Personnel Resort Rheumatoid Arthritis Role Running Science Scientist Stroke Students Talents Tissues Underrepresented Minority United States National Institutes of Health Woman career career development cell type cohort community building diversity and inclusion fly graduate student improved innate immune function male meetings microbial microbiota migration monocyte nervous system disorder neuroinflammation neutrophil new therapeutic target next generation novel particle pathogen peer posters professor programs racial population recruit role model skills supportive environment symposium technological innovation therapeutic target translational approach

项目摘要

PROJECT SUMMARY/ABSTRACT The Phagocyte Gordon Conference (GRC) and associated Gordon Research Seminar (GRS) will be held June 3-9, 2023 at Waterville Valley, NH. This will be the 22nd iteration of this GRC. Phagocytes are cells that have the capacity to engulf other cells or particles. Phagocytes include cells of the immune system such as neutrophils, monocytes/macrophages, and dendritic cells, analogous cell types in flies and worms, “nonclassical” phagocytes like microglia, and single-celled amoeba. While phagocytes are central to immunity, they also play roles in tissue homeostasis and development. When dysregulated, phagocytes contribute to prominent pathologies including atherosclerosis, diabetes, cancer, autoimmunity, and infectious diseases. The theme of the 2023 Phagocytes GRC is “Molecular and Cellular Diversity in Host Defense and Inflammation.” It will be the premier forum for sharing the most recent unpublished discoveries in phagocyte biology. Featured topics include phagocyte differentiation and plasticity, mechanisms of migration and phagocytosis, autophagy and cell death mechanisms, microglia and neuroinflammation, phagocytes in cancer, host-pathogen interactions, phagocyte crosstalk, interaction with the microbiota, and technological innovations in phagocyte biology. Novel translational approaches for phagocytes in different diseases will also be covered. Attendees are leading international scientists in cell biology, molecular genetics, microbiology, immunology, bioengineering, and clinical medicine. The average attendance is 148 attendees. In 2022 (postponed from 2021 due to COVID-19), 52.3% of attendees were women and 55.4% were graduate students or postdocs. The 2023 Phagocytes GRC features 13 female and 11 male invited speakers (54.2% female), with one keynote speaker, who will present their exciting unpublished findings. 37.5% of speakers identify as URM. Nine sessions will be chaired by discussion leaders who are experts in the field. As in past GRCs, 16 early-career scientists (graduate students, postdocs, assistant professors) will be selected for short talks based on submitted abstracts, and another 16 will give a brief preview of their poster. Approximately 120 posters will be presented in sessions that do not overlap with the talks. To enhance the participation and professional development of students and postdocs, a GRS will take place immediately prior to the start of the GRC (June 3-4). Organized and chaired by trainees, the GRS is an inclusive environment for the next generation of phagocyte scientists to share their research and build community. A comprehensive Diversity Plan will ensure that attendees and presenters are from diverse backgrounds and the conference environment is inclusive and equitable. The 2023 Phagocytes GRC and GRS will serve as a nexus for sharing cutting-edge unpublished research in phagocyte biology, thereby facilitating communication and collaboration between investigators studying different aspects of phagocytes, providing an inclusive and supportive environment for trainees and young investigators to network, and ultimately identifying translational and therapeutic targets of phagocytes in human health.

项目概要/摘要吞噬细胞戈登会议 (GRC) 和相关戈登研究研讨会 (GRS) 将于 6 月举行 2023 年 3 月 9 日，新罕布什尔州沃特维尔谷，这将是该 GRC 的第 22 次迭代。吞噬其他细胞或颗粒的能力，包括免疫系统细胞，例如中性粒细胞，单核细胞/巨噬细胞和树突状细胞，果蝇和蠕虫中的类似细胞类型，“非经典”吞噬细胞像小胶质细胞和单细胞阿米巴原虫一样，虽然吞噬细胞是免疫的核心，但它们也在组织中发挥作用。当体内平衡和发育失调时，吞噬细胞会导致显着的病理变化，包括动脉粥样硬化、糖尿病、癌症、自身免疫和传染病。2023年吞噬细胞的主题。 GRC 是“宿主防御和炎症中的分子和细胞多样性”。分享吞噬细胞生物学方面最新未发表的发现。特色主题包括吞噬细胞。分化和可塑性，迁移和吞噬机制，自噬和细胞死亡机制，小胶质细胞和神经炎症、癌症中的吞噬细胞、宿主-病原体相互作用、吞噬细胞串扰、与微生物群的相互作用以及吞噬细胞生物学的技术创新。还将涵盖吞噬细胞在不同疾病中的治疗方法。与会者都是国际领先的。细胞生物学、分子遗传学、微生物学、免疫学、生物工程和临床医学领域的科学家。 2022 年，平均出席人数为 148 人（因 COVID-19 而从 2021 年推迟），出席人数为 52.3%。女性，55.4% 是研究生或博士后 2023 年吞噬细胞 GRC 有 13 名女性。 11 位男性受邀演讲者（54.2% 女性），其中一位主讲人将展示他们精彩的演讲未发表的调查结果 37.5% 的发言者认为是 URM。九场会议将由讨论领袖主持。与过去的 GRC 一样，有 16 名早期职业科学家（研究生、博士后、助理）。教授）将根据提交的摘要被选出进行简短的演讲，另外 16 名将进行简短的预览大约 120 张海报将在与演讲不重叠的会议中展示。加强学生和博士后的参与和专业发展，GRS将举行 GRS 在 GRC 开始之前（6 月 3 日至 4 日）由学员组织和主持，是一个包容性的活动。为下一代吞噬细胞科学家分享他们的研究和建立社区的环境。全面的多元化计划将确保与会者和演讲者来自不同的背景会议环境具有包容性和公平性。2023 年吞噬细胞 GRC 和 GRS 将作为纽带。分享吞噬细胞生物学领域未发表的前沿研究，促进交流和研究吞噬细胞不同方面的研究人员之间的合作，提供了包容性和为受训者和年轻研究者建立网络提供支持性环境，并最终确定转化吞噬细胞在人类健康中的作用和治疗靶点。