2023 Phagocytes Gordon Research Conference and Gordon Research Seminar

2023吞噬细胞戈登研究大会暨戈登研究研讨会

• 批准号: 10683594
• 负责人: Sergio Daniel Catz
• 金额: $ 1.1万
• 依托单位: GORDON RESEARCH CONFERENCES
• 依托单位国家: 美国
• 财政年份: 2023
• 资助国家: 美国
• 起止时间: 2023-03-06 至 2024-02-29
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10683594
• 关键词: Adaptive Immune System; Address; Advocate; Alzheimer' s Disease; Amoeba genus; Area; Atherosclerosis; Atmosphere; Autoimmune Diseases; Autoimmunity; Autophagocytosis; Biochemistry; Biology; Biomedical Engineering; Brain; COVID-19; Cardiovascular Diseases; Cell Death; Cells; Cellular biology; Clinical; Clinical Medicine; Collaborations; Communicable Diseases; Communication; Communities; Dendritic Cells; Development; Diabetes Mellitus; Disabled Persons; Disease; Engineering; Ensure; Environment; Equity; Ethnic Population; Exclusion; Faculty; Feedback; Female; Financial Support; Fostering; Future; Genetic; Genomics; Goals; Growth; HIV-associated neurocognitive disorder; Health; Homeostasis; Host Defense; Hour; Human; Image; Immune system; Immunity; Immunology; Individual; Infection; Inflammation; Inflammatory Bowel Diseases; Innate Immune System; International; Knowledge; Lead; Learning; Location; Longevity; Lupus; Macrophage; Malignant Neoplasms; Mentors; Mentorship; Microbiology; Microglia; Mission; Molecular; Molecular Genetics; Multiple Sclerosis; National Institute of Allergy and Infectious Disease; Neurologic; New Hampshire; Pathologic; Pathologic Processes; Pathology; Phagocytes; Phagocytosis; Pharmacology; Play; Postdoctoral Fellow; Research; Research Personnel; Resort; Rheumatoid Arthritis; Role; Running; Science; Scientist; Stroke; Students; Talents; Tissues; Underrepresented Minority; United States National Institutes of Health; Woman; career; career development; cell type; cohort; community building; diversity and inclusion; fly; graduate student; improved; innate immune function; male; meetings; microbial; microbiota; migration; monocyte; nervous system disorder; neuroinflammation; neutrophil; new therapeutic target; next generation; novel; particle; pathogen; peer; posters; professor; programs; racial population; recruit; role model; skills; supportive environment; symposium; technological innovation; therapeutic target; translational approach

PROJECT SUMMARY/ABSTRACT The Phagocyte Gordon Conference (GRC) and associated Gordon Research Seminar (GRS) will be held June 3-9, 2023 at Waterville Valley, NH. This will be the 22nd iteration of this GRC. Phagocytes are cells that have the capacity to engulf other cells or particles. Phagocytes include cells of the immune system such as neutrophils, monocytes/macrophages, and dendritic cells, analogous cell types in flies and worms, “nonclassical” phagocytes like microglia, and single-celled amoeba. While phagocytes are central to immunity, they also play roles in tissue homeostasis and development. When dysregulated, phagocytes contribute to prominent pathologies including atherosclerosis, diabetes, cancer, autoimmunity, and infectious diseases. The theme of the 2023 Phagocytes GRC is “Molecular and Cellular Diversity in Host Defense and Inflammation.” It will be the premier forum for sharing the most recent unpublished discoveries in phagocyte biology. Featured topics include phagocyte differentiation and plasticity, mechanisms of migration and phagocytosis, autophagy and cell death mechanisms, microglia and neuroinflammation, phagocytes in cancer, host-pathogen interactions, phagocyte crosstalk, interaction with the microbiota, and technological innovations in phagocyte biology. Novel translational approaches for phagocytes in different diseases will also be covered. Attendees are leading international scientists in cell biology, molecular genetics, microbiology, immunology, bioengineering, and clinical medicine. The average attendance is 148 attendees. In 2022 (postponed from 2021 due to COVID-19), 52.3% of attendees were women and 55.4% were graduate students or postdocs. The 2023 Phagocytes GRC features 13 female and 11 male invited speakers (54.2% female), with one keynote speaker, who will present their exciting unpublished findings. 37.5% of speakers identify as URM. Nine sessions will be chaired by discussion leaders who are experts in the field. As in past GRCs, 16 early-career scientists (graduate students, postdocs, assistant professors) will be selected for short talks based on submitted abstracts, and another 16 will give a brief preview of their poster. Approximately 120 posters will be presented in sessions that do not overlap with the talks. To enhance the participation and professional development of students and postdocs, a GRS will take place immediately prior to the start of the GRC (June 3-4). Organized and chaired by trainees, the GRS is an inclusive environment for the next generation of phagocyte scientists to share their research and build community. A comprehensive Diversity Plan will ensure that attendees and presenters are from diverse backgrounds and the conference environment is inclusive and equitable. The 2023 Phagocytes GRC and GRS will serve as a nexus for sharing cutting-edge unpublished research in phagocyte biology, thereby facilitating communication and collaboration between investigators studying different aspects of phagocytes, providing an inclusive and supportive environment for trainees and young investigators to network, and ultimately identifying translational and therapeutic targets of phagocytes in human health.

项目摘要/摘要 Phagocyte Gordon会议（GRC）和相关的Gordon Research研讨会（GRS）将于6月举行 3-9，2023在新罕布什尔州沃特维尔山谷。这将是此GRC的22次迭代。吞噬细胞是具有 吞噬其他细胞或颗粒的能力。吞噬细胞包括免疫系统的细胞，例如中性粒细胞， 单核细胞/巨噬细胞和树突状细胞，类似的苍蝇和蠕虫中的类似细胞类型，“非经典”吞噬细胞 像小胶质细胞和单细胞变形虫一样。尽管吞噬细胞是免疫力的核心，但它们也在组织中起作用 稳态和发展。当失调时，吞噬细胞有助于重要的病理 动脉粥样硬化，糖尿病，癌症，自身免疫性和传染病。 2023年吞噬细胞的主题 GRC是“宿主防御和炎症中的分子和细胞多样性”。这将是主要论坛 分享吞噬细胞生物学的最新发现。特色主题包括吞噬细胞 分化和可塑性，迁移和吞噬作用的机制，自噬和细胞死亡机制， 小胶质细胞和神经炎症，癌症中的吞噬细胞，宿主病原体相互作用，吞噬细胞串扰， 与微生物群的相互作用以及吞噬细胞生物学的技术创新。小说翻译 还将涵盖不同疾病中吞噬细胞的方法。与会者领导国际 细胞生物学，分子遗传学，微生物学，免疫学，生物工程和临床医学领域的科学家。 平均出席人数为148名。 2022年（由于1921年为1921年推迟），52.3％的与会者 是女性和55.4％的研究生或博士后。 2023年吞噬细胞GRC具有13位女性 还有11位男性邀请演讲者（54.2％的女性），其中一位主题演讲者将表现出他们的兴奋 未发表的发现。 37.5％的演讲者将其视为URM。九个会议将由讨论领袖主持 谁是该领域的专家。与过去的GRC一样，16位早期科学家（研究生，博士后，助理 教授）将根据提交的摘要选择简短的会谈，另外16个将进行简短的预览 他们的海报。大约将在与谈判重叠的会议上介绍大约120张海报。到 加强学生和博士后的参与和专业发展，将进行GRS 在GRC开始之前（6月3日至4日）。 GRS是由培训组织和主持的 下一代吞噬细胞科学家分享其研究和建立社区的环境。一个 全面的多样性计划将确保与会者和演示者来自潜水员的背景和 会议环境具有包容性和公平性。 2023年的Phagocytes GRC和GRS将用作Nexus 用于共享吞噬细胞生物学的尖端未发表的研究，从而支持沟通和 研究吞噬细胞各个方面的研究人员之间的合作，提供包容性和 为受训者和年轻调查员提供网络的支持环境，并最终确定翻译 和吞噬细胞在人类健康中的治疗靶标。