Developmental Funds

发展基金

• 批准号: 10670854
• 负责人: Stephen D. Nimer
• 金额: $ 41.6万
• 依托单位: UNIVERSITY OF MIAMI SCHOOL OF MEDICINE
• 依托单位国家: 美国
• 财政年份: 2019
• 资助国家: 美国
• 起止时间: 2019-07-10 至 2024-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10670854
• 关键词: Address; Area; Award; Behavioral Research; Bioinformatics; Biometry; Cancer Center Support Grant; Cancer Control; Cancer Model; Catchment Area; Clinical Trials; Collaborations; Community Outreach; Comprehensive Cancer Center; Conduct Clinical Trials; Development; Epigenetic Process; Evaluation; Faculty; Financial Support; Flow Cytometry; Funding; Goals; Grant; Individual; Investigational Therapies; Investments; Leadership; Legal patent; Malignant Neoplasms; Molecular; Peer Review; Pilot Projects; Process; Publications; Research; Research Activity; Research Infrastructure; Research Personnel; Research Project Grants; Research Support; Resource Sharing; Science; Scientist; Series; Strategic Planning; Therapeutic; Translational Research; Tumor Biology; anticancer research; cancer genomics; clinical translation; community based research; community engagement; innovation; member; programs; recruit; service utilization; stem; tool; Address; Area; Award; Behavioral Research; Bioinformatics; Biometry; Cancer Center Support Grant; Cancer Control; Cancer Model; Catchment Area; Clinical Trials; Collaborations; Community Outreach; Comprehensive Cancer Center; Conduct Clinical Trials; Development; Epigenetic Process; Evaluation; Faculty; Financial Support; Flow Cytometry; Funding; Goals; Grant; Individual; Investigational Therapies; Investments; Leadership; Legal patent; Malignant Neoplasms; Molecular; Peer Review; Pilot Projects; Process; Publications; Research; Research Activity; Research Infrastructure; Research Personnel; Research Project Grants; Research Support; Resource Sharing; Science; Scientist; Series; Strategic Planning; Therapeutic; Translational Research; Tumor Biology; anticancer research; cancer genomics; clinical translation; community based research; community engagement; innovation; member; programs; recruit; service utilization; stem; tool

PROJECT SUMMARY: DEVELOPMENTAL FUNDS Shortly after assuming the Directorship of Sylvester Comprehensive Cancer Center (Sylvester) in 2012, Stephen D. Nimer, MD, initiated a center-wide effort to ensure that all cancer-relevant investments are strategically made. Nimer’s first goals were to systematically build needed research infrastructure, connect individuals and groups of investigators, build teams of scientists to create research programs for the center, and increase community engagement and outreach activities to gain a greater understanding of the diverse needs in Sylvester’s catchment area. In 2013, Sylvester leadership initiated a formal strategic planning process, resulting in the 2014-2018 Strategic Plan. This plan prioritized addressing the needs of Sylvester members, including the need for better shared resources (SRs), more reliable support for conducting clinical trials and translational science, and more financial support of outstanding cancer research. Since 2014, a total of $5.7M has been awarded via the peer-reviewed Intramural Funding Program, which includes nine award mechanisms to encourage new areas of cancer research, bridge investigator’s grant funding, support junior faculty, and promote innovative clinical trials that match Sylvester’s strategic goals and promote collaborative team science. The return on investment, calculated based on results stemming from the direct support of research projects, has been $25.2M in new grant funding, 22 publications (of which 64% are collaborative), new research tools, and three applications with one patent approved. To fulfill the needs of the three research programs, Sylvester has also invested $14M in the development of the Flow Cytometry, Onco-Genomics, Biostatistics and Bioinformatics, and Behavioral and Community-Based Research Shared Resources. Seventy percent of Sylvester members utilize services these shared resources provide. Additionally, Sylvester has invested $2.9M since 2016 in three highly translational developing shared resources: the Biospecimen, Cancer Modeling, and Molecular Therapeutics Shared Resources, for which CCSG Developmental Funds support is requested.

项目摘要：发展基金 在2012年担任西尔维斯特综合癌症中心（Sylvester）董事职位后不久， 医学博士Stephen D. Nimer发起了核心努力，以确保所有与癌症相关的投资都是 战略性地制作。 Nimer的第一个目标是系统地建立所需的研究基础架构，连接 个人和调查人员团体，建立科学家团队，为中心创建研究计划， 并增加社区参与和推广活动，以便对潜水员有了更深入的了解 西尔维斯特集水区的需求。 2013年，西尔维斯特领导人启动了正式的战略计划 过程，导致2014 - 2018年战略计划。该计划优先解决Sylvester的需求 成员，包括需要更好的共享资源（SRS），对进行临床的更可靠的支持 试验和转化科学，以及杰出癌症研究的更多财政支持。自2014年以来，总共 通过同行评审的壁内资金计划获得了570万美元的奖金，其中包括9个奖项 鼓励癌症研究新领域的机制，桥梁研究者的赠款资金，支持初级 教师，并促进与西尔维斯特战略目标相匹配的创新临床试验并促进合作 团队科学。根据直接支持的结果计算的投资回报 研究项目的新赠款资金为2520万美元，有22个出版物（其中64％是协作）， 新的研究工具和三个具有一项专利批准的应用程序。满足三项研究的需求 计划，西尔维斯特（Sylvester）还投资了1400万美元，以开发流式细胞术，Onco-Genomics， 生物统计学和生物信息学，以及基于行为和社区的研究共享资源。七十 Sylvester成员中的百分比利用这些共享资源提供的服务。此外，西尔维斯特拥有 自2016年以来，自2016年以来投资了290万美元，用于三个高度翻译的开发共享资源：生物镜，癌症 建模和分子疗法共享资源，CCSG开发基金支持是 要求。