Assessing a Novel Virtual Environment that Primes Individuals Living with AD/ADRD to Accomplish Activities of Daily Living.

评估一种新颖的虚拟环境，该环境可以帮助 AD/ADRD 患者完成日常生活活动。

• 批准号: 10668160
• 负责人: Mandy Salomon
• 金额: $ 8.49万
• 依托单位: MENTIA DTX, INC.
• 依托单位国家: 美国
• 财政年份: 2022
• 资助国家: 美国
• 起止时间: 2022-09-01 至 2023-08-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10668160
• 关键词: 3-Dimensional; Activities of Daily Living; Alzheimer' s Disease; Attention; Caregivers; Caring; Client; Communication; Data; Dementia; Ecological momentary assessment; Environment; Fostering; Health; Health Care Costs; Home; Impaired cognition; Individual; Longevity; Measures; Modality; Occupations; Outcome; Participant; Personal Satisfaction; Persons; Prevalence; Property; Quality of life; Residential Treatment; Risk; Site; Stimulus; Stress; Testing; Work; aging population; anxiety reduction; behavioral health; caregiver stress; cohort; cost; design; digital health; hands-on learning; human old age (65+); improved; member; memory care; new technology; novel; rehearsal; technology platform; virtual; virtual environment; virtual world

ABSTRACT The prevalence of Alzheimer’s disease and its related dementias (AD/ADRD) is growing due to increasing longevity and larger older-age populations. Care challenges to maintain the health and quality of life for persons living with dementia (PLWD) also creates a parallel health problem of persistent caregiver job stress leading to high staff turnover, additional risks to client and staff wellbeing, and higher operational costs. Improving the rate of completion of activities of daily living (ADL) has a known positive impact on the quality of life, health, and healthcare costs. Yet consistently completing ADLs, and without stress, remains a challenge. We hypothesize that undertaking virtual ADL activities will positively impact actual ADL activities resulting in more manageable and more efficient ADL completion, decreasing caregiver stress and improving the health, dignity, and quality of life for PLWD. Mentia is an early-stage digital health company that has developed DevaWorld™, a novel technology platform focused on improving behavioral health for people impacted by AD/ADRD. DevaWorld is unique in that it is designed for care dyads, with the PLWD being an active participant even though their cognitive decline may be severe. The platform consists of a media-rich 3D virtual home with interactive engagement stimuli that build communication within the care dyad and foster a sense of agency and identity. The proposed work aims to demonstrate tolerance and acceptance of DevaWorld and assess the impact of virtual ADL activities on both partners of the care dyad, paying particular attention to how the consistent rehearsal of ADLs inside DevaWorld by PWLD reduces caregiver stress. This work has two aims: Aim 1: Expand DevaWorld to include environments and activities most often cited as challenges to ADL completion. We hypothesize that players can prepare to perform ADLs via virtual world interactions. This aim entails co-designing settings, activities, and interactive avatar actions within DevaWorld to prime the player in selected ADLs. Aim 2: Demonstrate acceptance and feasibility of DevaWorld in a residential care setting. Qualitative assessments using ecological momentary assessments (EMAs) and quantitative measures of independence through ADL scale assessments will be used to study the impact of the cohort’s virtual ADLs on their actual ADLs (AIM 1). In this two-site study, the first outcome will be dyads’ acceptance and feasibility of DevaWorld in a real-world setting. The second outcome will measure DevaWorld’s potential for reducing anxiety within the dyad, leading to more efficient ADL completion.

抽象的 由于人口增加，阿尔茨海默病及其相关痴呆症 (AD/ADRD) 的患病率不断增加 长寿和老年人口数量增多，维持健康和生活质量面临着护理挑战。 痴呆症患者 (PLWD) 也会造成护理人员持续工作压力的平行健康问题 导致员工流动率高、客户和员工福祉面临额外风险以及更高的运营成本。 众所周知，提高日常生活活动 (ADL) 完成率对生活质量具有积极影响 然而，在没有压力的情况下持续完成 ADL 仍然是一个挑战。 我们寻求进行虚拟 ADL 活动将对实际 ADL 活动产生积极影响，从而导致 更易于管理和更高效地完成 ADL，减轻护理人员的压力并改善健康状况， PLWD 的尊严和生活质量。 Mentia 是一家早期数字健康公司，开发了新颖的技术平台 DevaWorld™ DevaWorld 致力于改善受 AD/ADRD 影响的人们的行为健康，其独特之处在于它是 专为护理二人组而设计，PLWD 是积极的参与者，尽管他们的认知能力可能会下降 该平台由一个富媒体的 3D 虚拟家庭组成，具有可构建的交互式参与刺激。 拟议的工作旨在促进护理二人内部的沟通并培养代理感和认同感。 展示对 DevaWorld 的容忍和接受，并评估虚拟 ADL 活动对双方的影响 护理二人组的合作伙伴，特别注意内部 ADL 的一致排练 PWLD 的 DevaWorld 可减轻护理人员的压力。 这项工作有两个目标： 目标 1：扩展 DevaWorld，纳入最常被视为 ADL 挑战的环境和活动 我们致力于让玩家可以通过虚拟世界交互来准备执行 ADL。 需要在 DevaWorld 中共同设计设置、活动和互动化身动作，让玩家做好准备 选定的 ADL。 目标 2：展示 DevaWorld 在定性护理环境中的接受度和可行性。 使用生态瞬时评估（EMA）和独立性定量测量进行评估 通过 ADL 量表评估将用于研究队列的虚拟 ADL 对他们实际的影响 ADL (AIM 1) 在这项双地点研究中，第一个结果将是双人组对 DevaWorld 的接受度和可行性。 第二个结果将衡量 DevaWorld 减少焦虑的潜力。 二元组，可以更有效地完成 ADL。