Stanford Diabetes Research Center

斯坦福糖尿病研究中心

基本信息

批准号：
10668992
负责人：
Seung K Kim
金额：
$ 196.74万
依托单位：
STANFORD UNIVERSITY
依托单位国家：
美国
项目类别：
财政年份：
2017
资助国家：
美国
起止时间：
2017-09-15 至 2027-06-30
项目状态：
未结题

来源：
https://reporter.nih.gov/project-details/10668992
关键词：
ATAC-seq Abbreviations Acceleration Affinity Automobile Driving Award Awareness Basic Science Behavioral Sciences Biological Assay Biological Sciences Biology Biomedical Engineering Biomedical Research California Cardiovascular system Caring Chemistry Child Health Chromatin Clinical Clinical Research Clinical Trials Clinics and Hospitals Collaborations Communities Community Healthcare Complications of Diabetes Mellitus Dedications Development Diabetes Mellitus Diagnosis Direct Costs Discipline Education Education and Outreach Engineering Event Evolution Faculty Focus Groups Fostering Foundations Funding Future Genomics Goals Growth Health Heart Human Immunologic Monitoring Immunology Institution Insulin-Dependent Diabetes Mellitus International Investigation Kidney Kidney Diseases Knowledge Leadership Learning Letters Malignant neoplasm of pancreas Maternal Health Medicine Mentors Metabolism Mission Modernization Modification National Center for Advancing Translational Sciences National Institute of Diabetes and Digestive and Kidney Diseases Natural regeneration Non-Insulin-Dependent Diabetes Mellitus Obesity Pancreas Pancreatic Adenocarcinoma Pediatric Hospitals Prevention Principal Investigator Productivity Regenerative Medicine Research Research Institute Research Personnel Research Support Resources Risk Taking Schools Science Scientist Seminal Services Signal Transduction Silicon Strategic Planning Technology Training Translating Translational Research Translations Transplantation United States National Institutes of Health Universities Work base care outcomes chimeric antigen receptor T cells chronic pancreatitis clinical care clinical center clinical development genome wide association study improved innovation islet medical schools member multidisciplinary next generation programs recruit research clinical testing scientific organization stem cell biology translational study

项目摘要

CENTER OVERVIEW: PROJECT SUMMARY/ABSTRACT The Stanford Diabetes Research Center (SDRC) embodies the culmination of a strategic plan by the Stanford University School of Medicine to create a premier program founded on a base of superb, collaborative investigators studying basic, clinical and translational problems in diabetes research. The SDRC mission is to foster innovation, new knowledge, and training in diabetes-related research, leading to improved diagnosis, treatment, and ultimately, prevention and cure of diabetes and its complications. Renewal of this P30 application will leverage diabetes research at Stanford University by providing crucial resources dedicated to supporting investigations and enrichment activities focused on diabetes. Stanford has a strong tradition of academic excellence, innovation, and clinical care, united in a true University on a single campus that fosters interactions between scientists and clinicians from different disciplines. Stanford is in the heart of Silicon Valley, an epicenter of innovation and calculated risk-taking, whose companies partner with SDRC faculty in unique and growing collaborations to advance diabetes research and care. Stanford neighbors two Universities of California (UC) at Berkeley, and at Davis, both elite research centers with a growing diabetes research base unconnected to a NIDDK DRC. The SDRC is comprised of 124 members from 3 Schools at Stanford, and from multiple Schools at UC Berkeley and UC Davis. SDRC members at Stanford currently have $65,044,250 in annual direct costs for diabetes-related research. SDRC members are organized by affinity groups focused on (i) Islet & Pancreas Biology, (ii) Metabolism & Signaling, (iii) Immunology, Transplantation & Stem Cell Biology, and (iv) Bioengineering & Behavioral Sciences. The SDRC consists of: (1) Administrative Component that coordinates scientific, organizational, enrichment, training and outreach activities, (2) Biomedical Research Component that recruits and selects members, and supervises 4 Research Cores that facilitate and enhance their research, and (3) a successful SDRC Pilot and Feasibility (P&F) Award Program that promotes the diabetes research of early stage investigators, and established scientists new to diabetes research. We propose to expand this Program to include a Regional P&F Program that supports research at UC Davis and Berkeley. NIH support for the SDRC is amplified by (1) Stanford’s sustained commitment to provide space and significant financial resources, (2) a comprehensive array of institutional research cores, which allow NIDDK funds to support specialized SDRC research cores devoted to diabetes research, (3) collaborative efforts with other Stanford research centers, and (4) SDRC member leadership of high-profile national diabetes research efforts. Since P30 funding began in 2017, the SDRC has evolved, including growth of its investigator base, intensified focus on translational research, and modification of core services to provide indispensable support for diabetes research. By multiple metrics, the SDRC is a force multiplier of innovation, whose members make seminal scientific contributions related to basic and translational diabetes, obesity, and metabolism research.

中央概述：项目摘要/摘要斯坦福糖尿病研究中心（SDRC）体现了斯坦福大学医学学院创建了一个在精湛的协作基础上建立的主要课程研究糖尿病研究中的基本，临床和翻译问题的研究者是SDRC的任务。促进与糖尿病相关研究的创新，新知识和培训，从而改善诊断，治疗，最终预防和治愈糖尿病，是并发症的。应用将通过提供致力于的重要资源来利用斯坦福大学的糖尿病研究支持调查的侵略激活重点是卓越的学术，创新和临床护理，在一个真正的校园中联合在一所真正的大学中斯坦福大学的科学家和临床医生之间的互动是硅的中心 Valley是创新和钙化冒险的中心，其公司与SDRC教职员工合作独特的Anige Anige Anige合作，以促进糖尿病研究和护理。加利福尼亚（UC）位于伯克利和戴维斯，这两个精英研究中心都在糖尿病研究基础增长与NIDDK DRC无关。加州大学伯克利分校和加州大学戴维斯分校的多所学校。与糖尿病相关研究的年度直接成本。（i）胰岛和串联生物学，（ii）代谢和信号传导，（iii）免疫学，移植和干细胞生物学，（iv）生物工程和行为科学。协调科学，组织，丰富，培训和外展活动，（2）生物医学研究招募和选择成员的组成部分，并监督4个研究核心，以促进和增强他们的研究，以及（3）成功的SDRC飞行员和可行性（P＆F）奖励计划，促进了您糖尿病研究人员的研究，并建立了糖尿病研究的科学家建议将此计划扩展到包括一个区域性宝洁计划，该计划支持加州大学戴维斯分校的研究伯克利对SDRC的支持由（1）斯坦福大量的财务资源，（2）一系列综合的Internitation Research核心，允许NIDDK 资金支持专门用于糖尿病研究的专业SDRC研究核心，（3）与斯坦福大学的其他研究中心和（4）SDRC成员的领导层是国家糖尿病研究自2017年P30的资金以来，SDRC的发展已经发展高度关注转化研究和修改核心服务以提供必不可少的支持对于多个指标的糖尿病研究，SDRC是创新的力量与基本和转化糖尿病，肥胖和代谢研究有关的开创性科学贡献。

项目成果

期刊论文数量（228）

专著数量（0）

科研奖励数量（0）

会议论文数量（0）

专利数量（0）

Insights into coral bleaching under heat stress from analysis of gene expression in a sea anemone model system

DOI：
10.1073/pnas.2015737117
发表时间：
2020-11-17
期刊：
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
影响因子：
11.1
作者：
Cleves, Phillip A.;Krediet, Cory J.;Pringle, John R.
通讯作者：
Pringle, John R.

Short-Term Repeatability of Insulin Resistance Indexes in Older Adults: The Atherosclerosis Risk in Communities Study.

老年人胰岛素抵抗指数的短期可重复性：社区研究中的动脉粥样硬化风险。

DOI：
10.1210/jc.2017-02437
发表时间：
2018
期刊：
The Journal of clinical endocrinology and metabolism
影响因子：
0
作者：
Poon,AnnaK;Meyer,MichelleL;Reaven,Gerald;Knowles,JoshuaW;Selvin,Elizabeth;Pankow,JamesS;Couper,David;Loehr,Laura;Heiss,Gerardo
通讯作者：
Heiss,Gerardo

Primary Care Providers in California and Florida Report Low Confidence in Providing Type 1 Diabetes Care.

DOI：
10.2337/cd19-0060
发表时间：
2020-04-01
期刊：
Clinical diabetes : a publication of the American Diabetes Association
影响因子：
0
作者：
Lal, Rayhan A;Cuttriss, Nicolas;Walker, Ashby F
通讯作者：
Walker, Ashby F

Long-term surveillance biopsy: Is it necessary after pediatric heart transplant?

长期监测活检：小儿心脏移植后是否有必要？

DOI：
10.1111/petr.13330
发表时间：
2019
期刊：
Pediatric transplantation
影响因子：
1.3
作者：
Peng,DavidM;Ding,VictoriaY;Hollander,SethA;Khalapyan,Tigran;Dykes,JohnC;Rosenthal,DavidN;Almond,ChristopherS;Sakarovitch,Charlotte;Desai,Manisha;McElhinney,DoffB
通讯作者：
McElhinney,DoffB

Scavenger receptor class B, type 1 facilitates cellular fatty acid uptake.

B 类清道夫受体 1 型促进细胞脂肪酸的摄取。