A Pilot for Enhancing Support for a Federated Framework of Biospecimens for Down Syndrome Research via the INCLUDE Data Hub

通过 INCLUDE 数据中心加强对唐氏综合症研究生物样本联合框架的支持的试点

• 批准号: 10671310
• 负责人: Joaquin M. Espinosa
• 金额: $ 39.99万
• 依托单位: CHILDREN'S HOSP OF PHILADELPHIA
• 依托单位国家: 美国
• 财政年份: 2020
• 资助国家: 美国
• 起止时间: 2020-09-26 至 2025-08-31
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10671310
• 关键词: Address; Cell Line; Clinical Data; Communities; DNA; Data; Data Element; Data Files; Development; Down Syndrome; Ensure; Freezing; Generations; Human; Institutes; Metadata; Nautilus; Participant; Pediatric Hospitals; Philadelphia; Process; Proteins; RNA; Reporting; Reproducibility; Research; Research Personnel; Resources; Sampling; Specimen; System; Testing; Time; Tissues; Update; base; biobank; cohort; data hub; data integration; data repository; data resource; repository; tool

PROJECT SUMMARY Under the proposed pilot, the respective biorepositories of the Children’s Hospital of Philadelphia and the Crnic Institute Human Trisome Project Biobank will partner with the INCLUDE Data Hub to define and implement the required workflows and tools to support biosample-based data/meta data integration. Such efforts will empower portal users to engage cohort creation and biosample use frameworks via the INCLUDE Data Hub and their downstream interactions with repositories as a combination of centralized and federated resources.

项目概要 根据拟议的试点，费城儿童医院和 Crnic 各自的生物样本库 研究所人类三体项目生物银行将与 INCLUDE 数据中心合作，定义和实施 支持基于生物样本的数据/元数据集成所需的工作流程和工具。 门户用户通过 INCLUDE 数据中心及其参与创建和生物样本使用框架 下游与存储库的交互作为集中和联合资源的组合。