Ambulatory monitoring of a vocal efficiency index to improve the clinical management of voice disorders

动态监测发声效率指数以改善发声障碍的临床管理

• 批准号: 10629293
• 负责人: Daryush Dinyar Mehta
• 金额: $ 35.7万
• 依托单位: MASSACHUSETTS GENERAL HOSPITAL
• 依托单位国家: 美国
• 财政年份: 2021
• 资助国家: 美国
• 起止时间: 2021-09-01 至 2026-05-31
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10629293
• 关键词: Accelerometer; Acoustics; Activities of Daily Living; Adult; Affect; Aftercare; Age; Air Movements; Ambulatory Monitoring; Behavior; Benchmarking; Calibration; Cellular Phone; Characteristics; Classification; Clinic; Clinical; Clinical Management; Clinical Treatment; Data; Diagnosis; Dysphonia; Ecological momentary assessment; Environment; Esthesia; Fatigue; Goals; Health; Health Care Costs; Home; Hour; Individual; Label; Laboratories; Lesion; Measures; Monitor; Muscle Tension; Neck; Nodule; Occupational; Output; Paralysed; Participant; Patients; Performance; Periodicals; Polyps; Population; Prevention; Probability; Production; Productivity; Psychometrics; Reading; Reporting; Series; Standardization; Surface; Techniques; Technology; Time; Translations; United States; Visual; Voice; Voice Disorders; Work; analog; clinical predictors; clinically significant; cohort; disability; flexibility; improved; indexing; innovation; microphone; participant enrollment; pressure; sensor; sex; social; sound; statistics; surgery outcome; vibration; vocal cord; wearable sensor technology; wireless

Project Summary/Abstract In the United States, voice disorders affect approximately 30% of the adult population at some point in their lives, with about 25 million individuals suffering at any given point in time. The impact of living with a voice disorder is far-reaching, and the societal burden reaches up to $13.5 billion dollars each year due to work-related disability, lost productivity, and direct healthcare costs. Individuals with voice disorders often suffer from heightened sensations of vocal effort and fatigue while speaking that are typically attributed to inefficient vocal function and behavior. Increasing vocal efficiency and decreasing vocal effort and associated vocal fatigue are often goals of clinical treatment paradigms. Thus, vocal efficiency is a highly desirable objective measure for the clinical management of voice disorders, particularly if it can be obtained via ambulatory monitoring to track vocal health and vocal behavior in a patient’s natural environment. The proposed project seeks to develop an index of ambulatory vocal efficiency that integrates estimates of subglottal pressure and vocal sound pressure level to monitor the vocal effort of patients being treated for phonotraumatic vocal cord lesions, non-phonotraumatic vocal hyperfunction, and unilateral vocal fold paralysis. Individuals with healthy vocal status will also be monitored as control subjects matched for sex, age, and occupational/vocal demands. An innovative wearable sensor technology using flexible circuits obtains synchronized data from a wireless neck-surface accelerometer and microphone to track the index of ambulatory vocal efficiency in real-world settings. Integrating the technology into a smartphone platform enables periodic prompting to prompt subjects to rate their level of vocal effort on a visual analog scale. The proposed work pursues critical goals of (a) investigating the clinical validity of the ambulatory vocal efficiency index in patients with voice disorders and vocally healthy matched controls and (b) assessing the ambulatory vocal efficiency index as an objective correlate of self-ratings of vocal effort. The impact of this work is significant because, for the first time, voice clinicians will be able to monitor vocal efficiency in naturalistic, real-world settings to improve the prevention, diagnosis, and treatment of voice disorders.

项目摘要/摘要 在美国，语音障碍在生活中的某个时刻影响大约30％的成年人口 在任何给定时间点，大约有2500万人受苦。语音障碍生活的影响是 深远的角度，由于与工作有关的残疾，每年的社会燃烧每年高达135亿美元， 失去生产力和直接医疗费用。语音障碍的人常常患有增强 在说话时，发声和疲劳的感觉通常归因于效率低下的人声功能和 行为。发声效率提高，声音努力和相关的人声疲劳通常是目标的目标 临床治疗范例。这是对临床的高度可取的客观测量的声音效率 语音障碍的管理，特别是如果可以通过卧床监测获得以跟踪声音健康的情况 和患者自然环境中的声音行为。 拟议的项目旨在开发卧床性声效率的指数，以整合估算的估计。 次球压力和声音音压水平，以监测接受治疗的患者的声音努力 Phonotraumatic的声带病变，非挥发声声性超功能和单方面的声带瘫痪。 具有健康人声状态的个人也将被监控，以符合性别，年龄和年龄的对照对象 占据/声音需求。使用灵活电路的创新可穿戴传感器技术获得 来自无线颈部表面加速度计和麦克风的同步数据，以跟踪卧床的索引 现实世界中的人声效率。将技术集成到智能手机平台中可以定期 促使受试者在视觉模拟量表上对他们的声音努力水平进行评分。拟议的工作 追求（a）研究患者门诊声效率指数的临床有效性的关键目标 语音障碍和声音健康的匹配对照，以及（b）评估门诊的人声效率 索引作为声音自我努力的客观相关。这项工作的影响很大，因为，对于 第一次，语音临床医生将能够监视自然主义，现实世界中的人声效率以改进 语音障碍的预防，诊断和治疗。