Remediation of Perfluorinated Chemicals in Water Using Novel High-Affinity Polymer Adsorbents

使用新型高亲和力聚合物吸附剂修复水中的全氟化学品

• 批准号: 10547559
• 负责人: Gokhan Barin
• 金额: $ 20.39万
• 依托单位: CYCLOPURE, INC.
• 依托单位国家: 美国
• 财政年份: 2018
• 资助国家: 美国
• 起止时间: 2018-04-01 至 2024-08-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10547559
• 关键词: Accreditation; Adsorption; Affect; Affinity; Agitation; Alpha Particles; American; Area; Carbon ion; Certification; Chemicals; Collaborations; Collection; Complex; Consult; Consultations; Counseling; Cyclodextrins; Cytoplasmic Granules; Data; Data Collection; Development; Engineering; Environment; Equipment; Excision; Feasibility Studies; Filtration; Health; Industrialization; International; Investigation; Ion Exchange Resins; Ions; Kinetics; Life Cycle Stages; Location; Manuals; Manufacturer Name; Methods; Municipalities; National Institute of Environmental Health Sciences; Natural regeneration; Organic solvent product; Particle Size; Performance; Phase; Poison; Poly-fluoroalkyl substances; Polymers; Powder dose form; Preparation; Privatization; Process; Production; Protocols documentation; Public Health; Publishing; Resistance; Resources; Risk; Safety; Section 8; Site; Small Business Innovation Research Grant; Societies; Solvents; Source; Structure; System; Technology; Testing; Training Activity; United States; United States Environmental Protection Agency; Water; Water Supply; Work; alternative treatment; base; beta-Cyclodextrins; commercialization; contaminated water; cost; cost effective; design; drinking water; experimental study; ground water; improved; industry partner; landfill; large scale production; manufacturing process; novel; operation; programs; remediation; uptake; water environment; water treatment

Abstract Contamination of water supplies by toxic per- and polyfluoroalkyl substances is a major health and environmental issue impacting society today. Given the environmental persistence of these contaminants and their established linkage to serious health risks, it is imperative that safe, efficient, and cost-effective PFAS remediation technologies be developed that can eliminate these contaminants from the U.S. water supplies. With the tightening of health-based contamination limits and the expansion of regulated PFAS structures, the impacts of PFAS contamination are now estimated to affect over 200 million Americans. NIEHS sponsored DEXSORB adsorbent represents a breakthrough solution for the safe, rapid, and cost-effective removal of short- and long- chain PFAS compounds, including PFOA and PFOS from water. It takes exacting technology to remove PFAS compounds at the trace levels being mandated by States and the EPA. Made from renewable cyclodextrins, DEXSORB’s ability to selectively target PFAS compounds at trace concentrations with rapid uptake, high capacity, and resistance to fouling make it ideally suited for use in private and municipal water treatment systems. Working with environmental partners, Cyclopure has demonstrated the superior performance and favorable life cycle economies of DEXSORB in pilot water treatment activities. To advance further, specific milestones that upon completion will help Cyclopure transition to full commercialization stage have been identified in this CRP proposal. Cyclopure’s main objective in this program will be to seek support for regulatory and manufacturing assistance. Both areas are critical prior to the commencement of full-scale manufacturing and commercialization activities. Safety and health related information and associated experimental data will be collected and organized for material registrations and certifications as required by regulatory agencies including EPA and NSF International. Activities under manufacturing assistance will support developing an optimal purification method that is expected to provide significant cost and process improvements in a full-scale manufacturing environment. Successful completion of this proposed work will enable Cyclopure to transition to large-scale production and work with industry partners to make DEXSORB available to provide PFAS removal for consumer and municipal applications.

抽象的 有毒的人类和多氟烷基物质污染供水是一种主要的健康和环境 发行影响社会的问题。考虑到这些污染物的环境持久性及其已建立的 与严重的健康风险联系，必须安全，高效和具有成本效益的PFA修复 开发了可以从美国供水中消除这些污染物的技术。与 收紧基于健康的污染极限和扩大受调节的PFA结构的影响 现在估计PFA污染会影响超过2亿美国人。 Niehs赞助了Dexsorb 吸附剂代表了一种突破性的解决方案 链PFAS化合物，包括水的PFOA和PFO。删除PFA需要严格的技术 国家和EPA要求的痕量水平的化合物。由可再生环糊精，制成 Dexsorb能够在快速吸收的痕量浓度下选择性地靶向PFAS化合物 容量和对结垢的抵抗使其非常适合用于私人和文化水处理系统。 与环境合作伙伴合作，Cyclopure证明了卓越的表现和良好的生活 dexsorb的循环经济在试点水处理活动中。进一步发展，具体的里程碑 完成后，将有助于在此CRP中确定自行车过渡到完全商业化阶段 提议。 Cyclopure在该计划中的主要目标是寻求支持和制造的支持 协助。在全面制造和商业化开始之前，这两个领域都是至关重要的 活动。将收集和组织与安全和健康相关的信息以及相关的实验数据 对于包括EPA和NSF在内的监管机构要求的物质注册和认证 国际的。制造援助下的活动将支持开发最佳净化方法 预计将在全面制造环境中提供大量的成本和流程改进。 成功完成这项拟议的工作将使自行车能够过渡到大规模生产和 与行业合作伙伴合作，使DexSorb可用，为消费者和文化提供删除PFA 申请。