2015 Cell Biology of Metals Gordon Research Conference

2015金属细胞生物学戈登研究会议

• 批准号: 8974528
• 负责人: Dennis J Thiele
• 金额: $ 2.52万
• 依托单位: GORDON RESEARCH CONFERENCES
• 依托单位国家: 美国
• 财政年份: 2015
• 资助国家: 美国
• 起止时间: 2015-06-01 至 2016-05-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8974528
• 关键词: Advocate; Applied Research; Bacteria; Basic Science; Biochemistry; Biological Models; Biological Process; Biology; Catalysis; Cell physiology; Cells; Cellular biology; Chemistry; Collaborations; Communicable Diseases; Communities; Disease; Environment; Fertilization; Fostering; Genetic; Growth and Development function; Homeostasis; Human; International; Ions; Knowledge; Life; Link; Medicine; Mentors; Metabolic Diseases; Metabolism; Metalloproteins; Metals; Microbe; Minority; Molecular; Nature; Organelles; Physicians; Physiology; Plants; Play; Proteins; Regulation; Research; Research Personnel; Resort; Role; Scientist; Series; Signal Transduction; Snow; Solutions; Structural Biologist; Suggestion; System; Technology; Therapeutic; Transition Elements; Underrepresented Minority; Whole Organism; Woman; absorption; biological systems; biomineralization; career; cofactor; high standard; human disease; lectures; meetings; member; metal complex; metal metabolism; novel diagnostics; pathogen; posters; prognostic; programs; public health relevance; structural biology; symposium; tool; transmission process; unpublished works

 DESCRIPTION (provided by applicant): The Gordon Research Conference (GRC) on the "Cell Biology of Metals: Mechanisms from Microbes to Humans" provides an outstanding forum for scientific exchanges, presentations and discussions in the emerging field of metals in biology, focusing on the acquisition, distribution, sensing and utilization of metals in proteins, cells and systems from bacteria to humans. This GRC series was initiated in 2005 and in the next cycle was immediately oversubscribed, illustrating that the meeting filled an important niche exploring the molecular mechanisms of metal utilization in proteins, organelles, and whole organisms. This conference has now become a cornerstone of the field and is unique in attacking broad research questions such as how cofactors are assembled to how metal ions play roles in metabolic and infectious diseases. The Cell Biology of Metals GRC is held every two years and has consistently attracted around 150 attendees. The Gordon Research Conference series is internationally renowned for the high-quality, cutting edge nature of its meetings, showcasing unpublished work, the program of this conference strives to maintain this high standard. The 2015 Cell Biology of Metals GRC will be held on July 26 - 31 at Mount Snow Resort in West Dover, VT. This application describes the program, which is organized around the theme of "Mechanisms from Microbes to Humans". Session topics include metals, reactivity, and the environment; structural biology of metalloproteins; metal homeostasis and disease; cofactor assembly, metal localization and signaling; metals at the host-pathogen axis; and tools and technologies for metals in biology. The conference will be comprised of keynote presentations, research and poster talks, poster discussions, and informal scientific discussions. This meeting will bring together an outstanding and diverse cadre of molecular and structural biologists, biochemists, geneticists, cell biologists physiologists and clinicians to interact and brainstorm on new discoveries, ideas and directions in basic and applied research on the cell biology of metals. Given the increase in the number of metabolic and infectious diseases linked to changes in cellular metal homeostasis, this meeting fills a critical niche for investigating the underlying mechanism(s) of these disorders and for brainstorming approaches for novel diagnostics, prognostics, and therapeutics.

 描述（由申请人提供）： 戈登研究会议（GRC）主题为“金属细胞生物学：从微生物到人类的机制”，为生物学金属新兴领域的科学交流、演示和讨论提供了一个杰出的论坛，重点关注金属的获取、分配、传感和研究。该 GRC 系列于 2005 年启动，在下一个周期中立即获得超额认购，这表明该会议填补了探索金属分子机制的重要空白。该会议现已成为该领域的基石，并且在解决广泛的研究问题（例如辅助因子如何组装以及金属离子如何在代谢和传染病中发挥作用）方面具有独特的作用。金属 GRC 每两年举办一次，一直吸引了约 150 名与会者。戈登研究会议系列因其会议的高质量、前沿性而享誉国际，展示了未发表的工作，本次会议的议程致力于保持这一高水平。标准。 2015 年金属细胞生物学 GRC 将于 7 月 26 日至 31 日在佛蒙特州西多佛的 Mount Snow Resort 举行。该应用程序描述了围绕“从微生物到人类的机制”的主题组织的会议主题包括金属、金属蛋白的反应性和环境；金属稳态和疾病；宿主-病原体轴上的金属定位和信号传导；会议将包括主题演讲、研究和海报演讲、海报讨论以及非正式的科学讨论，本次会议将汇集分子和结构生物学家、生物化学家、遗传学家、细胞生物学家和生理学家的杰出和多样化的骨干人员。鉴于与细胞金属稳态变化相关的代谢和传染病数量的增加，本次会议填补了一个关键的空白，旨在就金属细胞生物学基础和应用研究的新发现、想法和方向进行互动和集思广益。研究这些疾病的潜在机制，并集思广益以开发新的诊断、预后和治疗方法。