Superconducting scanner magnet for much lower cost, compact proton therapy systems

超导扫描仪磁体可实现成本更低的紧凑型质子治疗系统

• 批准号: 10546708
• 负责人: Alexander Otto
• 金额: $ 35.95万
• 依托单位: SOLID MATERIAL SOLUTIONS, LLC
• 依托单位国家: 美国
• 财政年份: 2022
• 资助国家: 美国
• 起止时间: 2022-09-22 至 2023-09-21
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10546708
• 关键词: Capital; Collaborations; Consumption; Copper; Cyclotrons; Development; Dimensions; Environmental Wind; Europe; Evaluation; Filament; Foundations; Funding; Goals; Height; High temperature of physical object; Length; Liquid substance; Malignant Neoplasms; Manufacturer Name; Marketing; Mechanics; Medical; Motor; Participant; Pathway interactions; Patients; Performance; Phase; Plug-in; Positioning Attribute; Price; Production; Property; Psychological reinforcement; Radial; Ramp; Reaction; Roentgen Rays; Shapes; Small Business Innovation Research Grant; Solid; System; Techniques; Technology; Temperature; Testing; Textiles; Time; Tissues; Treatment Cost; United States National Aeronautics and Space Administration; United States National Institutes of Health; Validation; X-Ray Medical Imaging; X-Ray Therapy; base; cold temperature; cost; density; design; experience; next generation; programs; proton beam; proton therapy; sensor; therapy design; therapy development; tumor; voltage; wound

Solid Material Solutions, LLC (SMS) SBIR Phase 1 ABSTRACT NIH FOA PA-21-259 Proposal Title: Superconducting scanner magnet for much lower cost compact proton therapy systems Proton Therapy (PT) is a proven, superior technique for treating cancer tumors compared to conventional X- ray therapy that can cause excessive healthy tissue damage. Yet it is available to less than 4% of the patients that would benefit from it, because for widespread usage, compact, much lower cost PT systems are required with much smaller magnets using High Temperature Superconductors (HTS) that generate higher fields at affordable operating conditions than current copper and Low Temperature Superconductor (LTS) magnets. Although PT system manufacturers have been developing more compact, lower cost PT systems, none have yet attained the combination of adequately low cost and reduced size to fit into much smaller treatment rooms, and full capabilities of the larger and costlier systems. It is specifically a key requirement for the PT system to fit into the small, low-cost treatment rooms that are already well established for low-cost X-Ray treatment. An essential component for the development of this ultra-compact, low-cost PT system is a much shorter HTS scanner magnet. This program will now develop a sufficiently short scanner magnet that recently became attainable due to breakthrough advances with the HTS-2212 material at Solid Material Solutions on wires, cables and coils for fast-ramp usage where inductive losses require advanced, low-loss conductor of the type required for this application. The specific product objective is a 4-coil scanner magnet that is one third the length of present magnets. It will include conduction cooling pathways, a cryo-envelope, current leads and control sensors. It will be readily plugged into the ultra-low-cost PT system and deliver the same performance as present magnets while also consuming 1/10th the electrical power. The Phase 1 program is aimed at establishing a specific 2212-based cable design and validating its production, along with design and fabrication of a low-loss demonstration coil with required radial build, current (Ic), and current density (Je) at the affordable cooling temperature regime of > 20K. This will be achieved by 1) Establishing specific wire and cable designs along with validation of their fabricability and properties 2) Developing specific capability to wind these cables into racetrack coil modules of the target radial build, overall shorter dimensions and with the required current and current densities to attain 2T at temperatures of 20 K or greater, and 3) Developing capability to fabricate coils of the target axial length from the racetrack modules, along with mechanical fixtures, current leads and voltage taps, followed by validation of its capability to generate the target 2 T at > 20 K in the dipole coil gap where the proton beam would be deflected. These developments will provide basis and justification for completing in a subsequent Phase II program, the commercial design, development and qualification of a full scale, conduction cooled coil set and magnet system that meets all requirements. When fully developed, this plug-in shorter scanner magnet will enable compact PT systems to be retro-fit height-wise into widely used treatment rooms of the kinds used for X-Ray therapy.

固体材料解决方案，LLC（SMS）SBIR阶段1摘要NIH FOA PA-21-259 提案标题：针对较低成本紧凑型质子治疗系统的超导扫描仪磁铁 与常规X-相比 射线疗法会导致过度健康的组织损伤。然而，不到4％的患者可以使用它 将受益于此，因为对于广泛的用法，紧凑，需要较低的PT系统，需要很多 使用高温超导体（HTS）的较小磁铁，在负担得起的运行中产生较高的字段 与电流铜和低温超导体（LTS）磁体相比。虽然PT系统 制造商一直在开发更紧凑，成本较低的PT系统，没有人达到的结合 足够低的成本和尺寸降低，适合小得多的治疗室，以及较大和较大的功能 更具成本效益的系统。它特别是PT系统适合小型低成本治疗室的关键要求 对于低成本X射线处理，已经建立了很好的确定。 这种超压缩，低成本PT系统开发的重要组成部分是HTS的短得多 扫描仪磁铁。该程序现在将开发出足够短的扫描仪磁铁，最近可以实现 由于HTS-2212材料在电线，电缆和线圈上的固体材料解决方案上的突破性提高。 电感损失需要该应用所需类型的高级低损失导体的快速升级使用情况。 特定的产品物镜是4线圈扫描仪的磁铁，是当前磁体长度的三分之一。会 包括传导冷却途径，冷冻层，电流导线和控制传感器。它将很容易插入 进入超低成本PT系统，并提供与当前磁铁相同的性能，同时也消耗1/10 电力。 第一阶段计划旨在建立特定的基于2212的电缆设计并验证其生产， 以及具有所需径向构建，电流（IC）和电流的低损坏演示线圈的设计和制造 在负担得起的冷却温度> 20k的密度（JE）。这将通过1）确定特定 电线和电缆设计以及验证其易于制定性和特性2）开发特定能力 将这些电缆将目标径向构建的赛道线圈模块缠绕，整体较短的尺寸以及 所需的当前和当前密度才能在20 K或更高的温度下达到2T，3）发展能力 从赛道模块中制造目标轴向长度的线圈，以及机械固定装置，电流导线和 电压龙头，然后验证其能力在偶极线圈间隙中生成靶标2 t> 20 k的能力。 质子梁将被偏转。 这些事态发展将为在随后的II阶段计划（即 商业设计，开发和资格的全尺度，传导冷却的线圈集和磁铁系统 满足所有要求。当完全开发时，此插件短扫描仪磁铁将使紧凑型PT系统能够 在广泛使用的X射线治疗类型的治疗室中，将其高度重现。