Hands-on Education and Research for Biomedical and Analytical Learning (HERBAL)

生物医学和分析学习的实践教育和研究（HERBAL）

• 批准号: 10665331
• 负责人: David C Rowley
• 金额: $ 26.77万
• 依托单位: UNIVERSITY OF RHODE ISLAND
• 依托单位国家: 美国
• 财政年份: 2023
• 资助国家: 美国
• 起止时间: 2023-07-03 至 2028-06-30
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10665331
• 关键词: Biomedical Research; Biotechnology; CCL7 gene; Chromatography; Clinical; Collaborations; Complement; Computers; Core Facility; Creativeness; Curiosities; Custom; Data; Development; Drug Compounding; Education; Educational Curriculum; Educational process of instructing; Educational workshop; Enrollment; Environment; Equipment; Event; Faculty; Food; Funding; Future; Game Based Learning; Geography; Goals; Government; Growth; Health; Herbal Medicine; High Pressure Liquid Chromatography; High School Faculty; High School Student; Home; Human; Imagination; Industrialization; Informatics; Institution; Instruction; Laboratories; Learning; Learning Module; Libraries; Mass Spectrum Analysis; Medicinal Plants; Medicine; Mentors; Mentorship; Methods; Molecular Biology; Names; Online Systems; Participant; Personal Satisfaction; Pharmaceutical Chemistry; Pharmacy facility; Plant Extracts; Plants; Positioning Attribute; Problem Solving; Property; Research; Research Personnel; Resources; Rhode Island; Role; Sampling; Science; Science, Technology, Engineering and Mathematics; Services; Societies; Source; Specimen; Students; Teacher Professional Development; Techniques; Technology; Therapeutic; Traditional Medicine; Training; Translating; Underrepresented Populations; Universities; career; college; design; digital media; drug discovery; experience; faculty mentor; high school; high throughput screening; informatics tool; innovation; inquiry-based learning; instructor; instrumentation; interest; junior high school; laboratory curriculum; liquid chromatography mass spectrometry; literacy; mathematical learning; method development; neighborhood disadvantage; online classroom; peer coaching; programs; rural area; secondary metabolite; skills; student training; summer program; summer research; teacher; teaching laboratory; theories; undergraduate research experience; undergraduate student; urban area

PROJECT SUMMARY/ABSTRACT Life-long education and learning in science, technology, engineering, and math (STEM) is necessary for society at large to adapt to a 21st century world and beyond. This is especially true at the high school level, where students begin to translate the imagination, discovery, and curiosity of middle school science to higher-level science and analysis, which will then advance further when university studies begin. Enhancing STEM literacy requires that science, technology, engineering, and math training be accessible and engaging to high school studies, well before university studies even begin. Faculty in the College of Pharmacy at the University of Rhode Island train upper-division undergraduate students in course-based undergraduate research experiences or CUREs in medicinal chemistry. Course participants become more than just learners; they become motivated researchers involved in a genuine scientific effort designed to enable future biomedical discoveries. One deliverable that students create during their medicinal chemistry course is a plant extract library from specimens in the Heber W. Youngken Jr. Medicinal Garden. This library is named PRISM - the Principal Rhode Island Secondary Metabolite library. We propose to extend the concept of a medicinal chemistry CURE and authentic research experiences to the high school level (9-12 grades) by developing HERBAL: Hands-on Education and Research for Biomedical and Analytical Learning. HERBAL will pair research in the laboratory with game-based online classroom modules to teach theory and methods of medicinal plant and herbal product analysis during the academic year. Summer sessions will allow students in the HERBAL program to analyze samples they themselves have generated on cutting-edge instrumentation available in the University of Rhode Island’s teaching laboratories. Additionally, we will focus on the beneficial wellness aspects of herbals and their integrated role in our biomedicine along with artistic and creative opportunities connecting medicinal plant research to drawing and illustration. The HERBAL program will consist of 1) teacher training workshops to educate instructors on how to deliver the HERBAL academic year program. 2) Teacher training will be followed by an academic laboratory course for students with game-based learning modules to train students in theory and application. 3) Following completion of the academic year, students will attend a summer course in chromatography, mass spectrometry, and informatics analysis. This summer course will be complemented with mentorship, career enhancement activities, guest speakers on herbal medicine, and artistic and wellness events. HERBAL’s focus on curricular and method development activities augmented with interactive digital-media based learning modules will shift the paradigm in how these students traditionally learn science, which will increase student interest in STEM topics and enhance their STEM identity.

项目概要/摘要 科学、技术、工程和数学 (STEM) 方面的终身教育和学习对于社会是必要的 适应 21 世纪及以后的世界尤其如此，在高中阶段尤其如此。 学生开始将中学科学的想象力、发现和好奇心转化为更高层次的知识 科学和分析，当大学学习开始时，这将进一步发展。 要求高中能够接受并参与科学、技术、工程和数学培训 早在罗德大学药学院的大学学习开始之前就开始了研究。 岛屿为高年级本科生提供基于课程的本科研究经验或 药物化学课程的参与者不仅成为学习者，而且变得积极主动。 研究人员致力于真正的科学努力，旨在实现未来的生物医学发现。 学生在药物化学课程中创建的成果是一个来自标本的植物提取物库 位于 Heber W. Youngken Jr. 药用花园 该图书馆被命名为 PRISM - 罗德岛校长。 我们建议扩展药物化学 CURE 和真实的概念。 通过开发 HERBAL：实践教育和 HERBAL 生物医学和分析学习研究将实验室研究与基于游戏的研究结合起来。 在线课堂模块，教授药用植物和草药产品分析的理论和方法 夏季课程将允许 HERBAL 项目的学生分析他们的样本。 他们自己已经在罗德岛大学的尖端仪器上产生了 此外，我们将重点关注草药及其综合有益健康的方面。 在我们的生物医学中的作用以及将药用植物研究与艺术和创意联系起来的机会 HERBAL 计划将包括 1) 教师培训讲习班以进行教育。 指导教师如何开展 HERBAL 学年课程 2) 教师培训之后将进行一次。 为学生提供学术实验课程，提供基于游戏的学习模块，对学生进行理论和实践方面的培训 3) 学年结束后，学生将参加暑期课程。 色谱法、质谱法和信息学分析将作为暑期课程的补充。 指导、职业提升活动、草药嘉宾演讲以及艺术和健康活动。 HERBAL 专注于通过交互式数字媒体增强的课程和方法开发活动 基于的学习模块将改变这些学生传统上学习科学的方式，这将 提高学生对 STEM 主题的兴趣并增强他们的 STEM 身份。