Annual Vitamin D Workshops

年度维生素 D 研讨会

基本信息

批准号：
10663280
负责人：
JoEllen Welsh
金额：
$ 5万
依托单位：
VITAMIN D WORKSHOP
依托单位国家：
美国
项目类别：
财政年份：
2014
资助国家：
美国
起止时间：
2014-06-15 至 2026-07-31
项目状态：
未结题

来源：
https://reporter.nih.gov/project-details/10663280
关键词：
Academia Address Advisory Committees Age Aging Applications Grants Applied Research Area Attention Award Basic Science Biological Process Biology Calcium Cells Cellular biology Cholecalciferol Chronic Chronic Disease Data Diabetes Mellitus Diet Disadvantaged Education Educational workshop Ethnic Origin Evaluation Exposure to Gene Expression General Population Genetic Goals Government Grant Health Health Professional Hormones Individual Industry Inflammatory Bowel Diseases Intake International Intestines Kidney Life Cycle Stages Light Malignant Neoplasms Medicine Metabolism Minority Mission Molecular Multiple Sclerosis Nuclear Receptors Outcome Participant Pathologic Processes Peer Review Physiological Policy Maker Population Population Group Population Heterogeneity Production Publications Research Research Personnel Resources Role Scholarship Scientist Series Serum Markers Skin Suggestion Supplementation Tissues Travel Ultraviolet Rays Vitamin D Vitamin D Deficiency Vitamin D supplementation Vitamin D2 Vitamin D3 Receptor age group age related bone bone metabolism calcium metabolism design interest lectures meetings oral communication posters prevent programs research and development scientific organization steroid hormone symposium translational scientist

项目摘要

The Vitamin D Workshop is a non-profit educational organization (est. 1977) whose mission is to organize scientific meetings on the metabolism, biological functions, and health effects of vitamin D. The goal of this R13 grant application to support a series of annual Vitamin D Workshops from 2021-2025. To date there have been 22 highly successful international Vitamin D Workshops which have typically attracted 200-300 basic researchers, translational scientists, clinicians, and policy makers from around the globe. Vitamin D is the precursor for an active steroid hormone that activates a nuclear receptor (the Vitamin D receptor, or VDR) to regulate gene expression. Its traditional role is to regulate the biology of cells in the bone, kidney, and intestine to control calcium and bone metabolism. Vitamin D can be obtained through diet and supplements as vitamins D2 and D3, and vitamin D3 can also be synthesized in skin upon exposure to UV light. Both the skin production of vitamin D and the molecular actions controlling calcium metabolism are suppressed by aging. Many studies have associated vitamin D status with a wide variety of physiologic and age-related, pathologic processes, e.g. cancer, diabetes, multiple sclerosis, and inflammatory bowel disease. While this research has generated considerable media attention, it has also led to many new questions about the molecular actions of the vitamin D hormone, the challenges of assessing vitamin D status and the optimal intake to prevent chronic diseases. It is not clear how aging, ethnicity and genetics influence vitamin D actions, and how requirements are altered in diverse populations. These issues are of great interest to scientists, health professionals and the general public. Collectively, these factors justify an annual meeting of vitamin D scientists to share research ideas and resources, discuss the emerging basic and applied data, and bring areas of controversy to light. The Specific Aims of the Vitamin D Workshops are: 1. To conduct a series of scientific conferences on the biology and health-relevant applications of vitamin D that address: • The latest peer-reviewed scientific research regarding the production, metabolism and mechanisms of action of vitamin D as they relate to physiologic state and age. • The concern of worldwide vitamin D deficiency across age groups as well as how to best identify, treat and prevent this condition in different populations and age groups. • The evidence on the adequate and safe levels of vitamin D intake and supplementation for individuals throughout the life course and in those with various age-related chronic disease states. • State of the art research approaches for studying vitamin D. 2. To bring together an interdisciplinary group of scientists from academia, medicine, industry, government and grassroots organizations with common interests in scientifically examining the health effects of vitamin D. 3. To encourage and recognize early-stage, minority and disadvantaged investigators conducting research on vitamin D and facilitate their interactions with established investigators through provision of scholarships, travel grants and young investigator awards. 4. To disseminate outcomes of the workshop through publication of the Conference Proceedings.

维生素 D 研讨会是一个非营利性教育组织（成立于 1977 年），其使命是组织关于维生素 D 的新陈代谢、生物功能和健康影响的科学会议。R13 的目标迄今为止，已申请资助一系列年度维生素 D 研讨会。 22 个非常成功的国际维生素 D 研讨会通常吸引了 200-300 名基础人士来自世界各地的研究人员、转化科学家、忠诚者和政策制定者是维生素 D。活性类固醇激素的前体，可激活核受体（维生素 D 受体，或 VDR）其传统作用是调节骨、肾和肠细胞的生物学。控制钙和骨骼代谢的维生素D可以通过饮食和维生素补充剂获得。 D2 和 D3 以及维生素 D3 也可以在暴露于紫外线时在皮肤中合成。维生素 D 的含量和控制钙代谢的分子作用会因衰老而受到抑制。维生素 D 状态与多种生理和年龄相关的病理过程相关，例如这项研究产生了癌症、糖尿病、多发性硬化症和炎症性肠病。引起了媒体的广泛关注，也引发了许多关于维生素分子作用的新问题 D 激素、评估维生素 D 状态的挑战以及预防慢性疾病的最佳摄入量。目前尚不清楚衰老、种族和遗传如何影响维生素 D 的作用，以及维生素 D 的需求量如何改变这些问题引起了科学家、卫生专业人员和公众的极大兴趣。总的来说，这些因素证明维生素 D 科学家召开年度会议是有必要的，以分享研究想法和资源，讨论新兴的基础和应用数据，并揭示有争议的领域。维生素 D 研讨会的具体目标是： 1. 举办一系列关于维生素 D 的生物学和健康相关应用的科学会议，地址： • 关于生产、代谢和机制的最新同行评审科学研究维生素 D 的作用与生理状态和年龄有关。 • 全球各年龄段维生素 D 缺乏症的关注以及如何最好地识别、治疗并在不同人群和年龄组中预防这种情况。 • 关于个人维生素 D 摄入和补充充足且安全水平的证据在整个生命过程中以及患有各种与年龄相关的慢性疾病状态的人中。 • 研究维生素D 的最先进的研究方法。 2. 汇集来自学术界、医学界、工业界、政府和社会各界的跨学科科学家团队草根组织对科学检验维生素 D 对健康的影响有着共同的兴趣。 3. 鼓励和表彰早期、少数族裔和弱势群体的研究人员进行研究维生素 D 并通过提供奖学金、旅行促进他们与知名研究人员的互动补助金和青年研究者奖。 4. 通过出版会议记录来传播研讨会的成果。

项目成果

期刊论文数量（5）

专著数量（0）

科研奖励数量（0）

会议论文数量（0）

专利数量（0）

Highlights from the 17th workshop on vitamin D, Chicago, IL, June 17-21, 2014.

2014 年 6 月 17 日至 21 日在伊利诺伊州芝加哥举行的第 17 届维生素 D 研讨会要点。

DOI：
10.1016/j.jsbmb.2015.01.024
发表时间：
2015
期刊：
The Journal of steroid biochemistry and molecular biology
影响因子：
0
作者：
Welsh,JoEllen;Bikle,DanielD;Lips,Paul
通讯作者：
Lips,Paul

Highlights from the 20th Workshop on Vitamin D in Orlando, Mar. 28-31, 2017.

2017 年 3 月 28 日至 31 日在奥兰多举行的第 20 届维生素 D 研讨会要点。

DOI：
10.1016/j.jsbmb.2017.11.010
发表时间：
2018
期刊：
The Journal of steroid biochemistry and molecular biology
影响因子：
0
作者：
Hewison,Martin;Fleet,JamesC;Demay,MarieB;Christakos,Sylvia;Bouillon,Roger;Welsh,JoEllen;White,JohnH
通讯作者：
White,JohnH

Highlights from the 18th workshop on vitamin D, Delft, The Netherlands, April 21-24, 2015.

2015 年 4 月 21 日至 24 日在荷兰代尔夫特举行的第 18 届维生素 D 研讨会要点。