Use of Digital Phenotyping to Understand Digital Media Influence on Adolescent Substance Use

使用数字表型来了解数字媒体对青少年药物使用的影响

• 批准号: 10661933
• 负责人: Meredith Gansner
• 金额: $ 19.31万
• 依托单位: BOSTON CHILDREN'S HOSPITAL
• 依托单位国家: 美国
• 财政年份: 2023
• 资助国家: 美国
• 起止时间: 2023-06-01 至 2027-05-31
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10661933
• 关键词: 18 year old; Address; Adolescent; Advertisements; Age; Alcohol consumption; Alcohols; Anxiety; Behavioral; Categories; Cellular Phone; Clinical; Communication; Communities; Complex; Cross-Sectional Studies; Data; Distress; Drug Experimentation; Drug Prescriptions; Drug usage; Emotions; Environmental Risk Factor; Epidemiology; Exposure to; Gender; Goals; Heterogeneity; Individual; Internet; Intervention; Language; Link; Longevity; Longitudinal Studies; Mental Depression; Methodology; Mission; National Institute of Drug Abuse; Outcome; Participant; Pathway interactions; Personal Communication; Pharmaceutical Preparations; Phenotype; Prevention strategy; Protocols documentation; Psychosocial Factor; Questionnaires; Recording of previous events; Reporting; Research; Research Personnel; Risk; Role; Sampling; Secondary to; Self Disclosure; Statistical Methods; Substance Use Disorder; Survey Methodology; Surveys; Technology; Teenagers; Time; Training; Training Programs; Victimization; Visualization; Youth; adolescent alcohol and drug use; adolescent drug use; adolescent substance use; aged; cyberbullying; design; digital; digital media; digital platform; emerging adult; ethnic minority; experience; high risk; high-risk adolescents; improved; longitudinal analysis; minority children; mortality; novel; overdose death; peer; psychiatric symptom; psychosocial; racial minority; racism; sensor; smartphone application; social; social factors; social media; substance use; tool; treatment planning

Project Summary This candidate is requesting support for a four-year program of training and research to use digital phenotyping to gain a novel understanding of how digital media influences like exposure to drug and alcohol- related content online can impact adolescent substance procurement and use. Addressing adolescent substance use is challenging due to the diverse social and environmental factors that can impact a youth’s decision to experiment with drugs or alcohol. Digital media use, including online exposure to substance-related content, is one such potential factor of growing daily influence in adolescent lives. However, little is currently known about how exposure to drug and alcohol-related content differs across media platforms (e.g. gaming, social media), nor whether exposure on one media platform may be more likely to facilitate drug procurement or precipitate an instance of substance use. This limitation in our understanding of these relationships is secondary to both recall bias and the cross-sectional survey methodology used in prior studies. This project will leverage novel digital phenotyping (DP) technology to collect smartphone sensor data in combination with active surveys about digital media exposures and substance use. In this manner, we plan to identify more accurately those digital media exposures and experiences that impact adolescent use of drugs and alcohol, and improve upon existing clinical guidance accordingly. In the proposed training plan, the candidate will build upon her previous experience in use of digital phenotyping to understand high-risk adolescent digital media use. Her training plan includes training in: 1) statistical methods for multivariate longitudinal analysis, 2) design and implementation of digital phenotyping tools that capture high-risk digital experiences/exposures in real time, 3) design and piloting of ecological momentary intervention protocols, and 4) responsible conduct of digital phenotyping research in adolescents with a history of substance use. In line with NIDA’s mission of identifying behavioral, environmental and social causes of substance use across the lifespan, this research plan will 1) determine which subtypes of digital media use are more frequently associated with exposure to drug and alcohol-related content and 2) assess which exposures are more frequently associated with instances of substance procurement and use. We will also explore the potential moderating effects of psychiatric symptoms and online victimization on the relationship between exposure to substance-related content and substance use. This study will be performed across 2 years in subjects between 15 and 18 years of age. A subsequent R01 proposal will then outline the design and pilot of an ecological momentary intervention protocol with the goal of intervening in real time upon digital exposures/experiences associated with adolescent substance use.

项目摘要 该候选人要求支持为期四年的培训和研究计划，以使用数字 表型以获得对数字媒体如何影响诸如暴露于药物和酒精的新了解 - 在线相关内容会影响青少年物质采购和使用。解决青少年 由于潜水员的社会和环境因素可能会影响年轻人 决定试验药物或酒精。数字媒体使用，包括在线接触与物质有关的 内容是在青少年生活中日常影响的潜在因素之一。但是，目前几乎没有 知道如何在媒体平台之间暴露于药物和酒精相关的内容差异（例如，游戏， 社交媒体），或者在一个媒体平台上的接触是否更可能促进毒品采购 或珍贵的用途实例。我们对这些关系的理解的局限性是 继发于召回偏见和先前研究中使用的横断面调查方法。这个项目 将利用新颖的数字表型（DP）技术来收集智能手机传感器数据 有关数字媒体暴露和物质使用的积极调查。通过这种方式，我们计划确定更多 准确地，那些数字媒体暴露和经验会影响青少年使用药物和酒精的使用， 并改善现有的临床指导。在拟议的培训计划中，候选人将建立 根据她以前使用数字表型来了解高风险青少年数字媒体的经验 使用。她的培训计划包括：1）用于多元纵向分析的统计方法，2）设计 并实施数字表型工具，可捕获现实的高风险数字体验/暴露 时间，3）生态瞬时干预方案的设计和试验，以及4）负责任的行为 具有药物使用史的青少年的数字表型研究。 符合NIDA的使命，该使命是确定使用物质的行为，环境和社会原因 在整个生命周期中，该研究计划将1）确定哪些数字媒体使用的亚型更多 通常与暴露于药物和酒精相关的含量以及2）评估哪些暴露是 与物质采购和使用实例更常见。我们还将探索 精神病症状的潜在调节作用和在线胜利对 暴露于与物质有关的含量和物质使用。这项研究将在两年内进行 15至18岁的受试者。然后，随后的R01提案将概述 生态瞬间干预方案，目的是实时介入数字 与青少年物质使用相关的暴露/经验。