Applying Item Response Theory to Improve Patient Reported Outcome Use in Dermatology Clinical Practice

应用项目反应理论改善皮肤科临床实践中患者报告的结果使用

基本信息

批准号：
10524835
负责人：
John Barbieri
金额：
$ 17.39万
依托单位：
BRIGHAM AND WOMEN'S HOSPITAL
依托单位国家：
美国
项目类别：
财政年份：
2022
资助国家：
美国
起止时间：
2022-07-01 至 2027-06-30
项目状态：
未结题

来源：
https://reporter.nih.gov/project-details/10524835
关键词：
Acne Address Advisory Committees Affect Area Atopic Dermatitis Award Calibration Caring Client satisfaction Clinic Clinical Clinical Research Computers Cost effectiveness research Data Dermatology Development Development Plans Disease Disease Outcome Electronic Health Record Environment Faculty Focus Groups Foundations Goals Health Services Research Health system Healthcare Hospitals Individual Information Systems Knowledge Learning Measurement Measures Mentored Patient-Oriented Research Career Development Award Mentors Methods Modernization Nature Outcome Outcome Measure Outcomes and Health Services Research Patient Care Patient Outcomes Assessments Patient-Focused Outcomes Patients Personal Satisfaction Persons Physical Function Physicians Positioning Attribute Property Psoriasis Psychometrics Pus Qualitative Research Quality of Care Quality of life Reporting Research Resources Review Literature Scientist Selection for Treatments Severity of illness Skin Supervision Surveys Symptoms Techniques Testing Time Training United States Validation Visit Woman Work base care outcomes career career development chronic inflammatory skin clinical care clinical practice comparative cost effectiveness concept mapping economic cost emotional functioning experience field study improved indexing innovation insight instrument knowledge base member novel patient oriented psychosocial research and development response skills skin disorder sound symptom management teledermatology tenure track theories treatment response

项目摘要

Project Summary/Abstract Research: While effective measurement of the patient’s perspective on their illness and its treatment provides complimentary information to objective disease severity, patient-reported outcomes capturing the lived experience of chronic inflammatory skin disease are rarely used in routine dermatology practice. Item response theory techniques can enable more efficient administration of patient-reported outcomes in the clinic, which can address barriers such as time to administer these measures. The purpose of this study is to 1. prioritize the outcome domains that are most meaningful to individuals with chronic inflammatory skin diseases such as acne, psoriasis, and atopic dermatitis; 2. evaluate the content validity of a novel Patient-Reported Outcomes Measurement Information System (PROMIS) profile measuring these domains; 3. field test and evaluate the validity of a novel PROMIS profile to capture the lived experience of chronic inflammatory skin disease. The overall objectives of this K23 award proposal are to improve the care of patients with chronic inflammatory skin diseases by developing a practical patient-reported outcome to measure the lived experience of these skin diseases, which will enable increased use of patient-reported outcomes in routine clinical care. Candidate: Dr. Barbieri’s long-term career goal is to become an independent, patient-oriented physician- scientist, with a focus on chronic inflammatory skin diseases, patient-reported outcomes, and health services research. His prior training has provided him with a foundational background in these areas. Environment: During the award period Dr. Barbieri will devote 80% of his time to clinical research and 20% to the clinical care of patients with chronic inflammatory skin disease such as acne, atopic dermatitis, and psoriasis. Dr. Margolis and Dr. Pusic, the candidate’s primary mentors, have directly supervised the training of numerous successful junior faculty members and Dr. Barbieri will benefit from his experience and enthusiasm for cultivating the careers of junior scientists. The Brigham and Women’s Hospital offers a rich training environment, including resources and expertise available in the Clinical Unit for Research Innovation and Trials (CUReIT) and Patient-Reported Outcomes, Value & Experience (PROVE) Center. Combined with the knowledge and expertise available in the Department of Dermatology and in Dr. Margolis’s and Dr. Pusic’s labs, these opportunities will provide an unparalleled opportunity to begin a career as a physician scientist. Career Development: With the support of his advisory committee, Dr. Barbieri’s training will focus on advanced psychometric techniques and qualitative research to develop a strong knowledge base with respect to patient-reported outcome development and validation. Completion of the proposed research and career development plan will give Dr. Barbieri the knowledge and skills to achieve scientific independence, transition to a tenure track faculty position, and build a strong foundation for a career in patient-oriented clinical research.

项目概要/摘要研究：虽然有效测量患者对其疾病及其治疗的看法可以提供对客观疾病严重程度、患者报告的结果捕捉生活的补充信息慢性炎症性皮肤病的经验很少用于常规皮肤科实践。理论技术可以在临床上更有效地管理患者报告的结果，这可以解决实施这些措施的时间等障碍。本研究的目的是 1. 确定优先顺序。对患有慢性炎症性皮肤病的个体最有意义的结果领域，例如痤疮、牛皮癣和特应性皮炎； 2. 评估新的患者报告结果的内容有效性；测量信息系统（PROMIS）配置文件测量这些领域；3.现场测试和评估一种新颖的 PROMIS 概况的有效性，用于捕捉慢性炎症性皮肤病的生活经验。该 K23 奖项提案的总体目标是改善慢性炎症性皮肤患者的护理通过开发实用的患者报告结果来衡量这些皮肤的生活体验来治疗疾病疾病，这将使患者在常规临床护理中更多地使用患者报告的结果。候选人：Barbieri 博士的长期职业目标是成为一名独立的、以患者为中心的医生—— 科学家，专注于慢性炎症性皮肤病、患者报告的结果和健康服务他之前的培训为他提供了这些领域的基础背景。环境：在获奖期间，Barbieri博士将投入80%的时间用于临床研究，20%的时间用于痤疮、特应性皮炎等慢性炎症性皮肤病患者的临床护理候选人的主要导师 Margolis 博士和 Pusic 博士直接监督了许多成功的初级教师和 Barbieri 博士将受益于他的经验和热情布莱根妇女医院为培养初级科学家的职业生涯提供了丰富的培训。环境，包括研究创新和试验临床部门提供的资源和专业知识 (CUReIT) 和患者报告结果、价值和经验 (PROVE) 中心。皮肤科以及 Margolis 医生和 Pusic 医生提供的知识和专业知识实验室，这些机会将为开始医师科学家的职业生涯提供无与伦比的机会。职业发展：在其顾问委员会的支持下，Barbieri 博士的培训将侧重于先进的心理测量技术和定性研究，以建立强大的尊重知识基础患者报告的结果开发和验证的完成。发展计划将为 Barbieri 博士提供实现科学独立、过渡的知识和技能终身教授职位，并为以患者为导向的临床研究职业生涯奠定坚实的基础。