Core A: Administration

核心A：管理

• 批准号: 10522805
• 负责人: Reuben S Harris
• 金额: $ 750.56万
• 依托单位: UNIVERSITY OF MINNESOTA
• 依托单位国家: 美国
• 财政年份: 2022
• 资助国家: 美国
• 起止时间: 2022-05-16 至 2025-04-30
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10522805
• 关键词: 2019-nCoV; Agreement; Annual Reports; Antiviral Agents; Biometry; Budgets; Businesses; COVID-19 pandemic; COVID-19 treatment; Clip; Collaborations; Communication; Communities; Conflict (Psychology); Consult; Consultations; Data Analyses; Decision Making; Development; Discipline; Disease Outbreaks; Educational workshop; Electronic Mail; Elements; Event; Experimental Designs; Future; Geographic Locations; Goals; Grant; Group Homes; Human Resources; Individual; Internet; Lead; Leadership; Legal; Logistics; Mainstreaming; Medial; Mediating; Mentors; Midwestern United States; Mind; Mission; National Institute of Allergy and Infectious Disease; Online Systems; Oral; Outcome; Peer Review; Pharmaceutical Preparations; Publications; Reagent; Recommendation; Reporting; Research Design; Research Personnel; Research Project Grants; Resource Sharing; Schedule; Scientist; Services; Site; Specific qualifier value; Students; Technology; Telephone; Time; Training; Training Activity; Travel; United States National Institutes of Health; Update; Viral; Virus; Voting; Work; antiviral drug development; drug discovery; experience; industry partner; material transfer agreement; meetings; member; new technology; novel; operation; organizational structure; outreach; pandemic disease; payment; prevent; programs; recruit; research and development; small molecule; social; symposium; virology; web site; 2019-nCoV; Agreement; Annual Reports; Antiviral Agents; Biometry; Budgets; Businesses; COVID-19 pandemic; COVID-19 treatment; Clip; Collaborations; Communication; Communities; Conflict (Psychology); Consult; Consultations; Data Analyses; Decision Making; Development; Discipline; Disease Outbreaks; Educational workshop; Electronic Mail; Elements; Event; Experimental Designs; Future; Geographic Locations; Goals; Grant; Group Homes; Human Resources; Individual; Internet; Lead; Leadership; Legal; Logistics; Mainstreaming; Medial; Mediating; Mentors; Midwestern United States; Mind; Mission; National Institute of Allergy and Infectious Disease; Online Systems; Oral; Outcome; Peer Review; Pharmaceutical Preparations; Publications; Reagent; Recommendation; Reporting; Research Design; Research Personnel; Research Project Grants; Resource Sharing; Schedule; Scientist; Services; Site; Specific qualifier value; Students; Technology; Telephone; Time; Training; Training Activity; Travel; United States National Institutes of Health; Update; Viral; Virus; Voting; Work; antiviral drug development; drug discovery; experience; industry partner; material transfer agreement; meetings; member; new technology; novel; operation; organizational structure; outreach; pandemic disease; payment; prevent; programs; recruit; research and development; small molecule; social; symposium; virology; web site

Core A – Administration ABSTRACT The primary goals of Core A – Administration are to provide leadership, logistical support, and coordinated communication for all members and collaborators of the Midwest AViDD Center in order to expedite the successful completion of all specific aims. The PI of Core A is Reuben Harris and the Co-I is Fang Li, which mirrors the overall leadership arrangement with Dr. Harris as corresponding Co-PI and Li as Co-PI. The specific aims of Core A are to 1) provide strong and consistent leadership; 2) provide services to Program scientists, collaborators, industry partners, and Scientific Advisory Board (SAB) members; and 3) coordinate center communications including meetings, workshops, and outreach efforts. The efficient administration of this multi- institutional team is essential for the successful development of novel small molecules with potential to become orally available drugs to treat SARS-CoV-2 (all projects) and other viruses with pandemic concern (at least one other virus to be targeted by each project). Harris and Li both have experience managing multi-investigator, matrixed grants, and they meet weekly to coordinate center management. They are supported by a full-time Executive Administrative Coordinator, who provides day-to-day administrative support and coordinates meetings, workshops, travel and other communication and networking activities. The Executive Leadership Team (ExLT), which consists of Project and Core PIs, meets monthly to review the status of scientific progress and discuss administrative business including budgets. The ExLT will also receive quarterly go/no-go recommendations on hit-to-lead (H2L) advancement from the HTL Committee, which may trigger appropriate budget adjustments. Core A will also coordinate an annual workshop for all center personnel, Scientific Advisory Board (SAB) members, and Industry Partners on dates juxtaposing an anticipated pan-AViDD consortium meeting at the NIH campus. The SAB will be appointed with consultation from NIAID AViDD network leadership and will participate in the annual workshop and other meetings as required by NIAID. Additional meetings of PIs, Project personnel, Core personnel, outside collaborators, and all center-associated personnel occur on a biweekly or monthly basis as specified by each component. Web-based zoom meetings facilitate the participation of all team members regardless of geographic location.

核心A - 管理 抽象的 核心A的主要目标 - 政府将提供领导，后勤支持和协调 向中西部Avidd中心的所有成员和合作者进行沟通，以便加快 成功完成所有特定目标。核心A的PI是Reuben Harris，Co-I是Fang Li， 反映了与Harris博士作为相应的Co-Pi和Li为Co-Pi的总体领导安排。具体 核心A的目标是1）提供强大而稳定的领导； 2）为程序科学家提供服务， 合作者，行业合作伙伴和科学顾问委员会（SAB）成员； 3）协调中心 沟通包括会议，研讨会和外展工作。有效地给予这一多数 机构团队对于成功发展新型小分子至关重要，有潜力 口服可用的药物以治疗SARS-COV-2（所有项目）和其他有关大流行的病毒（至少一个 每个项目都将针对的其他病毒）。 哈里斯（Harris）和李（Li）都有管理多重新投票员的经验 协调中心管理。他们得到了专职执行行政协调员的支持，他 提供日常的行政支持和协调会议，讲习班，旅行和其他 沟通和网络活动。执行领导团队（EXLT），由项目和 核心PI，每月开会以审查科学进步和讨论行政业务的状态，包括 预算。 EXLT还将从季度进行/不进行hit-to-Lead（H2L）进步的建议。 HTL委员会可能会引发适当的预算调整。核心A还将协调一年 所有中心人员，科学顾问委员会（SAB）成员和行业合作伙伴的讲习班 并列在NIH校园举行的预期的泛阿维德财团会议。 SAB将被任命 Niaid Avidd网络领导层的咨询，将参加年度研讨会和其他研讨会 NIAID要求的会议。 PI，项目人员，核心人员的其他会议，外部 合作者以及所有与中心相关的人员每两周或每月进行，按照每个人指定 成分。基于Web的缩放会议有助于所有团队成员的参与 地点。