Administrative Core

行政核心

• 批准号: 10515450
• 负责人: Phuoc T. Tran
• 金额: $ 13.06万
• 依托单位: UNIVERSITY OF MARYLAND BALTIMORE
• 依托单位国家: 美国
• 财政年份: 2022
• 资助国家: 美国
• 起止时间: 2022-08-04 至 2027-07-31
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10515450
• 关键词: Advisory Committees; Advocate; Affect; Applications Grants; Basic Science; Biology; Clinical Trials; Collaborations; Collection; Committee Members; Communication; Communities; Computing Methodologies; Data; Doctor of Medicine; Doctor of Philosophy; Ensure; Faculty; Financial Support; Funding; Genomics; Goals; Grant; Infrastructure; Institutes; International; Laboratories; Leadership; Malignant neoplasm of prostate; Maryland; Medicine; Mentors; Mission; Molecular; Neoplasm Metastasis; Normal tissue morphology; Occupational activity of managing finances; Oncology; Pathology; Patient-Focused Outcomes; Patients; Peer Review; Productivity; Radiation; Radiation Oncologist; Radiation Oncology; Radiation therapy; Radiobiology; Research; Research Contracts; Research Project Grants; Science; Site Visit; Techniques; Training; United States National Institutes of Health; Universities; University resources; Validation; Work; Writing; anticancer research; cancer site; career; clinically relevant; experience; improved; innovation; liquid biopsy; medical schools; meetings; metabolomics; metastatic process; multidisciplinary; next generation; outreach; professor; programs; radiation countermeasure; radiomics; symposium; tissue injury; Advisory Committees; Advocate; Affect; Applications Grants; Basic Science; Biology; Clinical Trials; Collaborations; Collection; Committee Members; Communication; Communities; Computing Methodologies; Data; Doctor of Medicine; Doctor of Philosophy; Ensure; Faculty; Financial Support; Funding; Genomics; Goals; Grant; Infrastructure; Institutes; International; Laboratories; Leadership; Malignant neoplasm of prostate; Maryland; Medicine; Mentors; Mission; Molecular; Neoplasm Metastasis; Normal tissue morphology; Occupational activity of managing finances; Oncology; Pathology; Patient-Focused Outcomes; Patients; Peer Review; Productivity; Radiation; Radiation Oncologist; Radiation Oncology; Radiation therapy; Radiobiology; Research; Research Contracts; Research Project Grants; Science; Site Visit; Techniques; Training; United States National Institutes of Health; Universities; University resources; Validation; Work; Writing; anticancer research; cancer site; career; clinically relevant; experience; improved; innovation; liquid biopsy; medical schools; meetings; metabolomics; metastatic process; multidisciplinary; next generation; outreach; professor; programs; radiation countermeasure; radiomics; symposium; tissue injury

The ROBIN Oligometastasis (ROBIN OligoMET) Center is focused on understanding how radiation therapy can affect the metastatic process in low-volume prostate cancer (PCa). The Administrative Core (Admin Core) leadership will be Phuoc Tran, M.D., Ph.D. (Contact PI) and Isabel Lauren Jackson (MPI). Dr. Tran is Vice Chair for Research and Professor of Radiation Oncology at the University of Maryland (UM). He is a practicing radiation oncologist with international recognition for his innovative clinical trials using stereotactic radiation in oligometastatic PCa. Dr. Jackson is the Director of the Nonclinical Radiation Biology Laboratory (NRBL) and Director of the Division of Translational Radiation Sciences (DTRS) within the Department of Radiation Oncology at UM. She has deep experience in managing multimillion-dollar federal contract-research programs on normal tissue injury and radiation countermeasures. Project leadership comprises a highly experienced and strong investigative team: Molecular Characterization Trial MCT is led by Drs. Phuoc Tran and Mark Mishra; Project 1 (Genomics, radiomics and liquid biopsies) will be led by Drs. Phuoc Tran, Amit Sawant and Lei Ren; Project 2 (Metabolomics and disparities) will be led by Dr. Nicole Simone Vice Chair for Research and Professor of Radiation Oncology at the Thomas Jefferson University (TJU); Resource and Cross-Training Cores will be led by Drs. Luigi Marchionni from Weill-Cornell Medicine (WCM), Amit Sawant and Lei Ren from UM. Supporting Drs. Tran and Jackson in the Administrative Core will be a Project Manager (Diana Newman). Ms. Newman has significant experience supporting similar programs including organizing site visits, outreach communications, organizing symposia, and coordination with NIH, BARDA and DARPA. The mission of our Administrative Core is to ensure that the research Projects and Research Cores are able to work together efficiently, set priorities for inter-Project collaborations, validate mechanisms across profiling platforms, and communicate research results internally and externally. We seek to be dynamic contributors to the NCI ROBIN Program, to collaborate with the NCI and the cancer research community, and to be a partner with patient advocates to connect basic research to improved patient outcomes. The leadership of ROBIN OligoMET Center is strongly committed to mentoring the next generation of leaders in radiation and metastasis research. Our ROBIN OligoMET Center includes two mid-career emerging leaders as Molecular Characterization Trial Leader (Dr. Mishra) and Core Director (Dr. Marchionni). Our ROBIN OligoMET Center has funding from the UM Radiation Oncology Department and funds from UMSOM to target early stage faculty and faculty from backgrounds underrepresented in science (UIS). Our Admin Core will achieve these goals through three Aims. Aim 1: Scientific and Financial Management of the ROBIN OligoMET Center. Aim 2: Communication and Review: External Advisory Committee (EAC), Internal Advisory Committee (IAC), Patient Advocates, and NCI. Aim 3: Pilot Research Grants Focusing on ESI and Diversity.

罗宾寡聚（Robin寡量）中心的重点是了解辐射疗法如何 影响低量前列腺癌（PCA）的转移过程。管理核心（管理员核心） 领导力是Phuoc Tran，医学博士，博士学位（与PI联系）和Isabel Lauren Jackson（MPI）。 Tran博士是副主席 马里兰州大学（UM）的研究和辐射肿瘤学教授。他是一个练习的辐射 肿瘤科医生因其创新的临床试验而获得国际认可，该试验使用立体定向辐射 寡聚PCA。杰克逊博士是非临床辐射生物学实验室（NRBL）和 辐射肿瘤学系内翻译辐射科学（DTRS）的负责人 在UM。她在正常管理数百万美元的联邦合同研究计划方面拥有深厚的经验 组织损伤和辐射对策。项目领导包括经验丰富且强大的 调查小组：分子表征试验MCT由DRS领导。 Phuoc Tran和Mark Mishra；项目1 （基因组学，放射线和液体活检）将由DRS领导。 Phuoc Tran，Amit Sawant和Lei Ren；项目2 （代谢组学和差异）将由Nicole Simone博士研究副主席和教授领导 托马斯·杰斐逊大学（TJU）的辐射肿瘤学；资源和交叉训练核心将被领导 由Drs。来自Weill-Cornell医学（WCM）的Luigi Marchionni，来自UM的Amit Sawant和Lei Ren。支持 博士。行政核心的Tran和Jackson将是项目经理（Diana Newman）。纽曼女士有 支持类似计划的丰富经验，包括组织现场访问，外展通信， 与NIH，Barda和Darpa组织研讨会，并协调。我们行政核心的任务 是为了确保研究项目和研究核心能够有效合作，为 项目间合作，验证跨分析平台的机制，并传达研究结果 内部和外部。我们寻求成为NCI Robin计划的动态贡献者，以与 NCI和癌症研究社区，并与患者拥护者建立联系，以联系基础研究 改善患者的预后。罗宾寡中中心的领导力强烈致力于指导 辐射和转移研究领域的下一代领导者。我们的罗宾寡中中心包括两个 职业生涯新兴领导者担任分子表征试验负责人（Mishra博士）和核心主任（博士 Marchionni）。我们的Robin寡聚中心有UM辐射肿瘤学部门的资金和资金 从UMSOM到针对早期的教师和来自科学（UIS）中代表性不足的教师。我们的 管理员核心将通过三个目标实现这些目标。目标1：科学和财务管理 罗宾寡聚中心。目标2：沟通和审查：外部咨询委员会（EAC），内部 咨询委员会（IAC），患者倡导者和NCI。 AIM 3：试点研究授予专注于ESI和 多样性。