Advancing Couple and Family Alcohol Treatment through Patient-Oriented Research and Mentorship

通过以患者为导向的研究和指导推进夫妻和家庭酒精治疗

• 批准号: 10644311
• 负责人: JULIANNE Christina Flanagan
• 金额: $ 19.18万
• 依托单位: MEDICAL UNIVERSITY OF SOUTH CAROLINA
• 依托单位国家: 美国
• 财政年份: 2023
• 资助国家: 美国
• 起止时间: 2023-06-01 至 2028-05-31
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10644311
• 关键词: Acceleration; Acute; Address; Adult; Affect; Aggressive behavior; Alcohol abuse; Alcohol consumption; Alcoholic Intoxication; Alcohols; Area; Award; Behavioral; Biological; Biological Markers; Cellular Phone; Chronic; Clinical; Clinical Sciences; Complement; Conflict (Psychology); Consultations; Couples; Data; Data Analyses; Development; Diagnosis; Diagnostic; Distress; Dose; Ecological momentary assessment; Economic Burden; Emotional; Enrollment; Ensure; Event; Family; Future; Goals; Health; Heavy Drinking; Individual; Influentials; Intervention; Intoxication; Investigation; Investments; K-Series Research Career Programs; Laboratories; Leadership; Literature; Longevity; Measurement; Measures; Mentors; Mentorship; Modality; Modeling; Morbidity - disease rate; National Institute on Alcohol Abuse and Alcoholism; Onset of illness; Oral; Outcome; Participant; Pathway interactions; Patient Self-Report; Perception; Physiological; Population; Post-Traumatic Stress Disorders; Prevention; Psychophysiology; Public Health; Qualifying; Recording of previous events; Reporting; Research; Research Personnel; Research Project Grants; Resources; Risk; Role; Science; Series; Severities; Standardization; Strategic Planning; Symptoms; Time; Training; Trauma; Treatment outcome; Violence; Work; alcohol abuse therapy; alcohol consequences; alcohol effect; alcohol misuse; alcohol research; alcohol use disorder; breath alcohol measurement; career; career development; coping; cost; design; drinking; equity, diversity, and inclusion; experience; heart rate variability; information processing; innovation; interest; intimate partner violence; mortality; multimodality; next generation; novel; partner aggression; patient oriented; patient oriented research; programs; response; secondary analysis; skills; social; sound; symptomatology; theories

ABSTRACT Alcohol misuse has a salient precipitous effect on intimate partner violence (IPV), which is a persistent public health crisis affecting approximately one-third of the U.S. population. Posttraumatic stress disorder (PTSD) is highly prevalent, has a clear causal effect on alcohol misuse, and it is a robust independent predictor of IPV. However, few studies have examined the combined effects of PTSD and alcohol misuse on IPV. This question is critical to address because effective prevention and treatment approaches for alcohol-related IPV are scant. Integrating these two siloed areas of the literature can help inform the development of novel, trauma-informed modalities for couples to produce stronger and more sustainable outcomes. Dr. Flanagan is the ideal candidate to advance the clinical science in this area. Under the proposed mid-career development award, she will accelerate her thriving patient-oriented alcohol research program by enhancing her skills with 1) oral alcohol administration, 2) intensive ambulatory assessment, and 3) psychophysiology. She will achieve these goals through expert consultation, didactic training, and implementation of the proposed research project. Her team will examine the combined effects of alcohol misuse and PTSD on alcohol-related IPV among couples (N=70) in both a controlled laboratory setting and in naturalistic settings. The study, which was designed to complement mentees’ independent research interests, will also compare outcomes across settings and explore heart rate variability as a physiological mechanism underlying the hypothesized relations. The invaluable protected time and resources provided by this K24 will enable Dr. Flanagan to achieve her primary goal of expanding her mentoring availability and skillset at this pivotal mid-career stage. She will engage a program of didactics and expert coaching to amplify her investment in diversity, equity, and inclusion in mentoring, leadership, and science. Achieving these synergistic objectives will accelerate the science of couple and family alcohol research and set the stage for innovative new dyadic treatments. This award will also ensure that Dr. Flanagan is equipped to support the next generation of enthusiastic new investigators and to ensure the longevity of this vital yet underrepresented area of the alcohol field.

抽象的 酒精遗产对亲密伴侣暴力（IPV）具有显着的精确效果，这是一个持续的公众 健康危机影响了大约三分之一的美国人口。创伤后应激障碍（PTSD）是 高度普遍，对滥用酒精有明显的因果作用，并且是IPV的强大独立预测指标。 但是，很少有研究检查了PTSD和滥用酒精对IPV的综合作用。这个问题 对于解决酒精相关的IPV的有效预防和治疗方法很少，这对于解决至关重要。 整合文献的这两个孤立区域可以帮助告知新颖，创伤的发展 夫妻的方式产生更强大，更可持续的结果。弗拉纳根博士是理想的候选人 推进该领域的临床科学。根据拟议的中期发展奖，她将 通过提高她的技能1）口服酒精来加快她蓬勃发展的以患者为导向的酒精研究计划 管理，2）强化室内评估和3）心理生理学。她将实现这些目标 通过专家咨询，教学培训和拟议研究项目的实施。她的团队 将检查滥用酒精和PTSD对夫妻中酒精相关IPV的综合作用（n = 70） 既有受控的实验室环境，又在自然主义环境中。该研究旨在完成 Menees的独立研究兴趣，还将比较跨环境的结果并探索心率 可变性是一种假设关系的物理机制。宝贵的保护时间 该K24提供的资源将使Flanagan博士实现她扩大她的主要目标 在这个关键的中间阶段指导可用性和技能。她将参与一个教学计划和 专家指导，以扩大她对多样性，公平性和在心理，领导才能包容和包容的投资 科学。实现这些协同目标将加速夫妇和家庭酒精研究的科学 并为创新的新二元疗法奠定了基础。该奖项还将确保弗拉纳根博士等效 支持下一代热情的新调查人员，并确保这一至关重要的寿命 酒精场的代表性不足。