J: NRSA Training Core

J：NRSA 培训核心

• 批准号: 10642862
• 负责人: Kate L Lapane
• 金额: $ 41.05万
• 依托单位: UNIV OF MASSACHUSETTS MED SCH WORCESTER
• 依托单位国家: 美国
• 财政年份: 2015
• 资助国家: 美国
• 起止时间: 2015-08-14 至 2025-05-31
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10642862
• 关键词: Abbreviations; Accountability; Address; Biometry; Cardiovascular system; Clinical; Clinical Research; Communication; Competence; Conflict of Interest; Data Science; Development; Development Plans; Ecosystem; Educational Curriculum; Effectiveness; Eligibility Determination; Entrepreneurship; Environment; Epidemiology; Fostering; Funding; General Practitioners; Good Clinical Practice; Health; Health Sciences; Individual; Inosine Diphosphate; Interest Group; Learning; Master of Science; Medical; Mentors; Modeling; National Center for Advancing Translational Sciences; National Research Service Awards; Pathway interactions; Population; Postbaccalaureate; Postdoctoral Fellow; Principal Investigator; Qualifying; Reproducibility; Research; Research Design; Resources; Rotation; Scholars Program; School Nursing; Science; Self Assessment; Structure; Students; System; TNFSF15 gene; Teacher Professional Development; Training; Training Programs; Translational Research; Work; Writing; clinical investigation; cohort; commercialization; community engagement; education research; graduate school; implementation science; new product development; pre-doctoral; programs; recruit; responsible research conduct; skills; tool

Contact PD/PI: Luzuriaga, Katherine NRSA-Training-001 (003) PROJECT SUMMARY/ABSTRACT – J. NRSA TRAINING CORE The TL1 program addresses the NCATS unmet need of a prepared translational research workforce. Since the first cohort was recruited in 2016, the TL1 program has transformed training in translational research at UMMS from a fragmented, siloed training model to a collaborative training environment, well integrated with UMCCTS resources. The TL1 program provides didactic training to develop domain expertise, rigorous research, team science, and communication skills. The TL1 specific aims are to: 1) Assure core competence in clinical and translational research for highly qualified pre- and early post-doctoral trainees through the provision of a multi- faceted, rigorous TL1 program; 2) Facilitate a broad spectrum of clinical and translational research responsive to unmet health needs; 3) Enable efficiency, quality, effectiveness, and reproducibility in the development of new products or approaches; and 4) Foster transdisciplinary training and team science in research. To achieve these aims, we have developed 5 structured Research Pathways in Entrepreneurship and Commercialization, Data Science, Community Engagement, Implementation Science, and a Generalist Pathway. To assure a di- verse trainee population with respect to clinical background, disciplinary perspective, and those underrepre- sented in the biomedical sciences, we recruit from national and local pools of eligible candidates. TL1 trainees self-assess their competency in clinical and translational research as defined by the national CTSA Consortium and work with mentoring teams to create an individualized competency-based curriculum providing formal and informal opportunities to develop research skills. Locally, our Council to Advance Trainees and Scholars leads efforts to reduce redundancy and to integrate translational learning opportunities across the training ecosystem at UMMS. Regionally and nationally, our trainees learn to use CTSA tools (e.g., i2b2) and engage with CTSA collaborators (e.g., shared mentoring, research rotations, retreats). In the next funding period, our TL1 Pro- gram will share our rigor and reproducibility curriculum for use by the CTSA consortium. Abbreviations: BERD - Biostatistics, Epidemiology, and Research Design; CATS - Council on Advancing Scholars; COI - Conflict of Interest; CTRP - Clinical and Translational Research Pathway; CVD – Cardiovascu- lar; DIG - Diversity Interest Group; FDSP - Faculty Development Scholar Program; GCP - Good Clinical Prac- tice; GSBS - Graduate School of Biomedical Sciences; GSN - Graduate School of Nursing ; IDP - Individual Development Plan; IMSD - Initiative for Maximizing Student Development ; MPI - Multiple Principal Investiga- tor; MSCI - Master of Science in Clinical Investigation; MSTP - Medical Science Training Program; PiPSS - Projects in Progress Seminars; PQHS - Population and Quantitative Health Sciences; PREP - Post Baccalau- reate Research Education Program; R2D2 - Reproducibility and Replication Discovery Dialogue ; RCR - Re- sponsible Conduct of Research; SPRC - Science Participation Research Center; TRAcs - Translational Re- search Accelerator System; WAG - Writing Accountability Group Page 1795 Project Summary/Abstract Contact PD/PI: Luzuriaga, Katherine NRSA-Training-001 (003) NARRATIVE – J. NRSA TRAINING CORE The TL1 program provides training for predoctoral and early-stage postdoctoral trainees to develop domain expertise, rigorous research, team science, and communication skills. The TL1 program addresses the NCATS need for a prepared translational research workforce. Page 1796

联系 PD/PI：Luzuriaga、Katherine NRSA-Training-001 (003) 项目摘要/摘要 – J.NRSA 培训核心 TL1 计划解决了 NCATS 自成立以来未满足的转化研究人员需求。 第一个队列于 2016 年招募，TL1 项目改变了 UMMS 转化研究的培训 从分散、孤立的培训模式到与 UMCCTS 良好集成的协作培训环境 TL1 计划提供教学培训，以培养领域专业知识、严谨的研究和团队。 TL1 的具体目标是： 1) 确保临床和沟通技能的核心能力。 通过提供多方面的支持，为高素质的博士前和早期博士后学员进行转化研究 多方面、严格的 TL1 计划；2) 促进广泛的临床和转化研究响应 满足未满足的健康需求；3) 提高开发的效率、质量、有效性和可重复性 新产品或方法；以及 4) 促进跨学科培训和团队科学研究以实现这一目标。 为了实现这些目标，我们开发了 5 条创业和商业化的结构化研究途径， 数据科学、社区参与、实施科学和通才途径 与临床背景、学科观点和代表性不足的受训者群体相反 我们从国家和地方合格的 TL1 学员库中招募生物医学科学领域的学员。 根据国家 CTSA 联盟的规定，自我评估其在临床和转化研究方面的能力 并与指导团队合作创建基于能力的个性化课程，提供正式和 在当地，我们的高级学员和学者委员会领导着发展研究技能的非正式机会。 减少冗余并努力整合整个培训生态系统的转化学习机会 在 UMMS，我们的学员学习使用 CTSA 工具（例如 i2b2）并参与 CTSA。 合作者（例如，共同指导、研究轮换、静修）。 gram 将分享我们严谨且可重复性的课程，供 CTSA 联盟使用。 缩写：BERD - 生物统计学、流行病学和研究设计；CATS - 推进委员会； 学者；COI - 利益冲突；CTRP - 临床和转化研究途径； lar；DIG - 多元化兴趣小组；FDSP - 教师发展学者计划；GCP - 良好临床实践 - GSBS - 生物医学科学研究生院 - IDP - 个人； 发展计划；IMSD - 最大化学生发展倡议 - 多项主要调查 - tor；MSCI - 临床研究理学硕士；PiPSS - 正在进行的项目研讨会；PQHS - 人口和定量健康科学 - PREP - Post Baccalau - reate 研究教育计划；R2D2 - 再现性和复制发现对话； 负责任的研究行为；SPRC - 科学参与研究中心；TRAcs - 转化研究 搜索加速器系统；WAG - 写作责任小组 第1795页 项目概要/摘要 联系 PD/PI：Luzuriaga、Katherine NRSA-Training-001 (003) 叙述——J.NRSA 培训核心 TL1项目为博士前和早期博士后培训生提供培训 培养领域专业知识、严谨的研究、团队科学和沟通技巧。 该计划满足了 NCATS 对准备好的转化研究人员的需求。 第1796页

项目成果

Rising to the Occasion: A National Nursing Home Study Documenting Attempts to Address Social Isolation During the COVID-19 Pandemic.

• DOI: 10.1016/j.jamda.2023.05.018
• 发表时间: 2023-08
• 期刊: JOURNAL OF THE AMERICAN MEDICAL DIRECTORS ASSOCIATION
• 影响因子: 7.6
• 作者: Lapane, Kate L.;Lim, Emily;Mack, Deborah S.;Hargraves, J. Lee;Cosenza, Carol;Dube, Catherine E.
• 通讯作者: Dube, Catherine E.

The relationship between restless sleep and symptoms of the knee: data from the Osteoarthritis Initiative.

• DOI: 10.1007/s10067-020-05531-4
• 发表时间: 2021-06
• 期刊: Clinical rheumatology
• 影响因子: 3.4
• 作者: Lapane KL;Shridharmurthy D;Harkey MS;Driban JB;Dubé CE;Liu SH
• 通讯作者: Liu SH

The Inverse OARSI-OMERACT Criteria Is a Valid Indicator of the Clinical Worsening of Knee Osteoarthritis: Data From the Osteoarthritis Initiative.

• DOI: 10.3899/jrheum.200145
• 发表时间: 2021-03
• 期刊: The Journal of rheumatology
• 作者: Driban JB;Harkey MS;Price LL;Lo GH;McAlindon TE
• 通讯作者: McAlindon TE

Exposure to Weight Management Counseling Among Students at 8 U.S. Medical Schools.

• DOI: 10.1016/j.amepre.2020.10.026
• 发表时间: 2021-05
• 期刊: American journal of preventive medicine
• 影响因子: 5.5
• 作者: Ashe KM;Geller AC;Pendharkar JA;Pbert L;Crawford S;Clark MA;Frisard CF;Eno CA;Faro J;Ockene JK
• 通讯作者: Ockene JK

A Latent Approach to Understanding Pain in Nursing Home Residents Who are Unable to Self-Report Pain.

• DOI: 10.2147/jpr.s302305
• 发表时间: 2021
• 期刊: Journal of pain research
• 影响因子: 2.7
• 作者: Forrester S;Mbrah A;Lapane KL
• 通讯作者: Lapane KL