Methods for Early Phase Translation of Basic Science into Behavioral Treatments to Improve Health

将基础科学早期转化为行为治疗以改善健康的方法

• 批准号: 10642822
• 负责人: SYLVIE NAAR
• 金额: $ 20.95万
• 依托单位: FLORIDA STATE UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2022
• 资助国家: 美国
• 起止时间: 2022-09-01 至 2026-08-31
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10642822
• 关键词: Acceleration; Address; Adult; Attention; Basic Behavioral and Social Science Research; Basic Science; Behavior Therapy; Behavioral; Behavioral Research; Cancer Prevention Trial; Cardiovascular Diseases; Chronic Disease; Clinical Trials Design; Consultations; Control Groups; Course Content; Creativeness; Dedications; Development; Diabetes Mellitus; Discipline; Dose; Drops; Educational Curriculum; Educational process of instructing; Educational workshop; Ensure; Evaluation; Exposure to; Faculty; Goals; Grant; Health; Health Care Costs; Health Promotion; Health behavior; Intervention; Intervention Studies; Knowledge; Learning; Link; Malignant Neoplasms; Mentors; Methodology; Methods; Minority; Modeling; Participant; Persons; Phase; Process; Public Health Practice; Publications; Qualitative Evaluations; Quantitative Evaluations; Questionnaires; Research Personnel; Risk Factors; Sampling; Scientist; Smoking; Specific qualifier value; Surveys; Techniques; Technology; Time; Trainers Training; Training; Translational Research; Translations; Unhealthy Diet; United States National Institutes of Health; Video Recording; Work; aged; attributable mortality; behavioral and social science; bench to bedside; cancer prevention; cancer therapy; career; clinical practice; course development; curriculum development; design; drug development; effective therapy; efficacy testing; follow-up; improved; innovation; interest; investigator training; lectures; literacy; modifiable risk; mortality; premature; prevent; programs; public health priorities; recruit; sedentary lifestyle; skill acquisition; skills; social science research; success; therapy design; therapy development; treatment optimization; web site; webinar

PROJECT SUMMARY To strengthen behavioral interventions for improve health, as in cancer prevention and treatment, and increase their dissemination into clinical practice, what is needed is: (1) more attention to phased T1 translation from basic behavioral and social sciences research to applied behavioral intervention development; and (2) more focus on early-phase treatment development by promoting the use of new and innovative methodologies to answer commonly asked questions about basic treatment design. This skills development course aims to train 100 intervention scientists (Fellows) at any academic rank but who have an interest in behavioral treatment development to target cancer and related health behaviors. Training will take place over 6 months including a 3-day workshop followed by bi weekly webinars with 25 Fellows per session. Learning will be multi-directional and will feature didactic, interactive, and applied teaching techniques. A train-the-trainer model is integrated throughout the course. Optional follow-up activities include consultation and mentoring with faculty. The curriculum will be offered by expert faculty who will teach a phased approach to intervention development, new and innovative methods that are well-suited to answer common questions that arise during health behavior treatment development. Among the methodologies are dose-finding methods, mixed methods to maximize ecological validity of treatments, approaches for small samples, tailoring and adaptive treatments, and methods to determine the timing and choice of appropriate control groups. The Specific Aims of the course are: 1) To successfully recruit and train 100 Fellows dedicated to behavioral interventions relevant for cancer prevention/treatment and related health behaviors over the 4-year grant period, with substantial minority representation (25 Fellows per year); 2) To increase the skills of Fellows in a phased approach, with associated innovative methods and designs for T1 translation of BSSR. 3) To conduct an ongoing evaluation of the success of the skills development course based upon three basic metrics: (a) perceived value; (b) the reach of the course based upon website hits, number of applications, and train the trainer activities; and (c) the impact of the course on the career trajectories of the Fellows (publications, grants). 4) To conduct ongoing curriculum development and refinement, as well as dissemination via technology, based upon results of quantitative and qualitative evaluations and new methodologies emerging over the grant period.

项目摘要 加强行为干预以改善健康，如预防癌症和治疗，以及 将其传播到临床实践中，需要的是：（1）更多关注分阶段T1 从基本的行为和社会科学研究转换为应用行为干预 发展; （2）通过促进新的使用，更多地关注早期治疗的发展 以及回答有关基本治疗设计的常见问题的创新方法。这 技能发展课程旨在培训100名干预科学家（研究员），但 对行为治疗发展有兴趣的人，以靶向癌症和相关健康 行为。培训将在6个月内进行，包括3天的研讨会，然后是BI Weekly 网络研讨会，每个会议25名研究员。学习将是多方向的，并且具有教义， 互动和应用教学技术。整个训练训练模型都集成了 课程。可选的后续活动包括与教师的咨询和指导。课程将 由专家教师提供的，他将教授分阶段的干预开发方法， 非常适合回答健康行为过程中出现的常见问题的创新方法 治疗开发。方法中包括剂量调查方法，混合方法 最大化治疗方法的生态有效性，小样本的方法，裁缝和适应性 治疗方法和方法来确定适当对照组的时间和选择。具体 该课程的目的是：1）成功招募和训练100名专门行为的研究员 与预防癌症预防/治疗以及相关健康行为相关的干预措施4年 赠款期，大量少数派代表（每年25名研究员）； 2）提高技能 以分阶段方法为基础的研究员，以及相关的创新方法和设计，用于T1翻译 BSSR。 3）对基于技能发展课程的成功进行持续评估 在三个基本指标上：（a）感知值； （b）基于网站命中的课程范围， 申请数量，并培训培训师活动； （c）课程对职业的影响 研究员的轨迹（出版物，赠款）。 4）进行持续的课程开发和 根据定量和定性的结果，改进以及通过技术传播 在整个赠款期间出现的评估和新方法。