The Enduring Effects of COVID-19 Infection on Psychological Factors, Cognition, and Social Integration inRecently Homeless Veterans

COVID-19 感染对最近无家可归的退伍军人的心理因素、认知和社会融入的持久影响

• 批准号: 10640039
• 负责人: Jonathan Wynn
• 金额: --
• 依托单位: VA GREATER LOS ANGELES HEALTHCARE SYSTEM
• 依托单位国家: 美国
• 财政年份: 2023
• 资助国家: 美国
• 起止时间: 2023-01-01 至 2026-12-31
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10640039
• 关键词: 2019-nCoV; Acute; Address; Affect; American; Anxiety; Area; Buffers; COVID-19; COVID-19 impact; COVID-19 pandemic; Chronic; Cities; Cognition; Cognitive; Community Integration; Contracts; Coronavirus Infections; Country; Cross-Sectional Studies; Data; Databases; Economics; Environment; Exhibits; Face; Family; Home; Homelessness; Housing; Individual; Infection; Intervention; Interview; Joints; Knowledge; Long-Term Effects; Los Angeles; Measures; Mental Depression; Mental Health; Nature; Neurologic; Outcome; Participant; Pattern; Persons; Phase; Population; Post-Traumatic Stress Disorders; Psychological Factors; Psychological Impact; Recording of previous events; Recovery; Relaxation; Research Proposals; Risk Factors; SARS-CoV-2 infection; Sampling; Series; Social Distance; Telephone; Textiles; Time; Uncertainty; United States; Vaccinated; Vaccination; Veterans; Virus; Virus Diseases; Vulnerable Populations; administrative database; cognitive function; combat; coping; coronavirus disease; effective therapy; experience; future pandemic; improved; infection risk; mental function; metropolitan; pandemic disease; pandemic impact; prospective; protective factors; psychological outcomes; recruit; remote assessment; resilience; service utilization; social; social integration; treatment strategy

The COVID-19 Pandemic, which became widespread in the United States in March 2020, has directly impacted nearly everyone in our country. An exceptionally large number of Americans have contracted the SARS-CoV-2 virus. The long-term effects of being infected by the virus are unknown, but it is evident that many of those who contracted the virus are continuing to exhibit severe cognitive and psychological impacts months after becoming infected. While the pandemic has affected everyone in some way, it may have disproportionately impacted those who are the most vulnerable of our population, including those who are homeless. Homelessness in Veterans is a major national issue, and the pandemic has only heightened the need to address the issue. Many homeless Veterans either lived in unsheltered environments or in congregate settings that may have limited their ability to socially distance, putting them at increased risk for infection. Furthermore, those who have recently obtained housing often face a disruption in their daily routines and social and family networks, which may have been exacerbated by the pandemic. This, in turn, could have further reduced social integration and resulted in increased mental health burden. Critical knowledge gaps exist in that we do not know how long negative cognitive and mental health outcomes from infection last, how pervasive they are in those who have been infected, or how infection affects vulnerable Veterans (for this proposal, Veterans with a history of chronic homelessness). This research proposal will address these crucial knowledge gaps by examining the effects of infection on cognitive functioning, mental health, and social integration in recently housed Veterans vs. Veterans without a history of chronic homelessness. In an exploratory aim, we will examine if risk and protective factors (resilience, coping, tolerance of uncertainty) and VA service utilization buffered the negative effects of infection. In the proposed 4-year study we will recruit a total of 400 Veterans across four large metropolitan areas (Los Angeles, Houston, Orlando, and Seattle) using VA databases to identify those who have been infected and have a history of chronic homelessness. There will be four groups in total, with 100 participants in each group, consisting of those infected vs. never infected and those with or without a history of chronic homelessness. All participants will be assessed remotely every 2 months over an 18-month period. By identifying the impact of COVID infection on vulnerable and non-vulnerable Veterans, this study can provide valuable information not available in any VA database or other study. The VA must plan for and provide effective treatment strategies to combat long-term effects of infection as the pandemic moves into the endemic phase. The results from this study will help guide interventions and treatments that ultimately are aimed at improving community integration in vulnerable Veterans and Veterans who may become infected with COVID- 19 in the coming years.

1920年3月在美国广泛普遍存在的COVID-19-大流行直接已直接 影响了我们国家的几乎每个人。一大批美国人签约了 SARS-COV-2病毒。被病毒感染的长期影响尚不清楚，但很明显 许多感染病毒的人都在继续表现出严重的认知和心理影响 被感染几个月后。虽然大流行以某种方式影响了每个人，但它可能有 不成比例地影响了我们人口中最脆弱的人，包括那些 无家可归。退伍军人无家可归是一个主要的国家问题，大流行只会增加 需要解决这个问题。许多无家可归的退伍军人要么生活在非庇护的环境中或聚集 可能限制其社交距离能力的设置使他们处于感染风险的增加。 此外，那些最近获得住房的人经常在日常工作和社交中受到干扰 和家庭网络，这可能因大流行而加剧。反过来，这可能会进一步 减少了社会融合，导致心理健康负担增加。存在批判知识差距 我们不知道最后的认知和心理健康结果多长时间，直到感染了多长时间，多么普遍 他们在那些被感染的人中，或感染如何影响脆弱的退伍军人（对于此提案， 有慢性无家可归历史的退伍军人）。 这项研究建议将通过检查感染对这些关键知识差距 最近住所的退伍军人与退伍军人的认知功能，心理健康和社会融合 慢性无家可归的历史。为了探索目的，我们将检查风险和保护因素是否 （弹性，应对，不确定性的耐受性）和VA服务利用率缓解了感染的负面影响。 在拟议的4年研究中，我们将在四个大都市地区招募400名退伍军人（Los） Angeles，Houston，Orlando和Seattle）使用VA数据库来识别被感染的人 有慢性无家可归的历史。总共将有四组，每组100名参与者， 由那些被感染与永不感染的人以及没有慢性无家可归史的人组成。全部 参与者将在18个月的时间内每2个月进行一次远程评估。 通过确定互联感染对脆弱和不可侵害的退伍军人的影响，本研究可以提供 在任何VA数据库或其他研究中均未提供有价值的信息。 VA必须计划并提供 随着大流行进入流行的有效治疗策略，以应对感染的长期影响 阶段。这项研究的结果将有助于指导最终针对的干预措施和治疗 改善可能感染Covid-的弱势退伍军人和退伍军人的社区融合 在未来几年中。