T32 for Training in Microbiology and Infectious Diseases

T32 用于微生物学和传染病培训

基本信息

批准号：
10640896
负责人：
Celia Goulding
金额：
$ 14.1万
依托单位：
UNIVERSITY OF CALIFORNIA-IRVINE
依托单位国家：
美国
项目类别：
财政年份：
2019
资助国家：
美国
起止时间：
2019-08-19 至 2024-07-31
项目状态：
已结题

来源：
https://reporter.nih.gov/project-details/10640896
关键词：
Communicable Diseases Microbiology Training

项目摘要

PROJECT SUMMARY This proposal is a new application for five years of funding to support Training in Microbiology and Infectious Diseases at UC Irvine. The primary objective of this Training Program is to provide doctoral students with integrated training in three focus areas: 1) microbial structure and metabolism, 2) microbe- host interactions, and 3) microbial communities. The rationale behind this training structure is that there will be tremendous value in individuals with a fluency in these related areas that are vital to combating and/or exploiting microbes to positively impact human health and the environment. The Training Program will leverage areas of excellence at UCI in microbial ecology, microbe-host interactions, and structural biology to bring together faculty trainers with expertise in microbial pathogenesis, molecular genetics, metabolism, structure, immunity and infectious diseases, and microbial diversity. The program will be comprised of 18 well-funded training faculty (10 women, 8 men) from the School of Biological Sciences and the School of Medicine at UCI. The faculty mentors conduct research on microbiology and infectious diseases at the molecular, cellular, organismal, population, and community levels. UCI has a strong history in the fields of microbiology and infectious disease research, as the Pacific-Southwest Regional Center of Excellence in Biodefense and Emerging Infectious Diseases was housed at UCI from 2005- 2014. The Training Program will ensure that the trainees will be equipped with the necessary tools and expertise to pursue a productive and independent career in microbiology. In addition to faculty mentorship, the trainees will benefit from seminars, journal clubs, research in progress talks, and an annual symposium. Trainees will also receive funds to travel to and present their research at a national meeting in their field. Finally, UCI is home to the NIH-funded GPS-BIOMED program, which will ensure that trainees have exposure to career development seminars, workshops, and mentorship throughout their training. The application requests support for three predoctoral trainees, who will be drawn from students who enroll at UCI through one of several gateway or departmental programs, including the Cellular & Molecular Biosciences Program, Interdepartmental Neuroscience Program, Mathematical, Computational & Systems Biology Program, Medical Scientist Training Program (MSTP), and the departmental Ecology & Evolutionary Biology Program. The mean incoming GPA for this cohort of students over the last five years was 3.61, reflecting a strong overall academic performance by the potential trainees. On average over the last five years, 23% of the training-grant eligible entering students were under-represented minorities. UCI has been recognized as a Hispanic-serving institution (HSI) and an Asian American, Native American, and Pacific Islander serving institution (AANAPISI), and the Training Program is expected to reflect this rich cultural and ethnic diversity on the UCI campus.

项目摘要该提案是为五年资金提供的新申请，以支持微生物学培训和 UC Irvine的传染病。该培训计划的主要目的是提供doortoral 在三个重点领域接受综合培训的学生：1）微生物结构和代谢，2）微生物主机互动和3）微生物群落。这种训练结构背后的理由是对于在这些相关领域流利的人来说，对打击至关重要的个人将是巨大的价值和/或开发微生物以积极影响人类健康和环境。培训计划将利用微生物生态学，微生物 - 宿主相互作用和结构的UCI的卓越领域生物学将具有微生物发病机理的专业知识，分子遗传学，将教师培训汇集在一起，代谢，结构，免疫力和传染病以及微生物多样性。该程序将是由18个资金资助的培训学院（10名女性，8名男性）组成，来自生物科学学院和UCI医学院。教师导师进行有关微生物学和传染性的研究分子，细胞，生物体，种群和社区水平的疾病。 UCI有强大微生物学和传染病研究领域的历史，作为太平洋南部地区从2005年开始，UCI居住在生物脱节和新兴传染病的卓越中心。 2014年。培训计划将确保学员将配备必要的工具和从事微生物学领域的富有成效和独立职业的专业知识。除了教师属性，学员将受益于精神分子，期刊俱乐部，正在进行的研究和年度研讨会。受训人员还将获得资金，以前往并向国家展示研究在野外开会。最后，UCI是NIH资助的GPS-BIOMED计划的所在地，这将确保学员将在整个职业发展研讨会，研讨会和精神训练中接触他们的训练。申请请求支持三名副学员的支持，他们将从通过几个门户或部门计划之一参加UCI的学生，包括细胞与分子生物科学计划，部门间神经科学计划，数学，计算与系统生物学计划，医学科学家培训计划（MSTP）和部门生态与进化生物学计划。该队列的平均传入GPA 过去五年的学生为3.61，反映了潜在的学员。在过去五年中，平均有23％的培训符合条件参加学生的人数不足。 UCI被公认为是西班牙裔服务机构（HSI）和亚裔美国人，美国原住民和太平洋岛民服务机构（AANAPISI），以及预计该培训计划将反映出UCI校园的这种丰富的文化和种族多样性。

项目成果

期刊论文数量（10）

专著数量（0）

科研奖励数量（0）

会议论文数量（0）

专利数量（0）

High-Fiber, Whole-Food Dietary Intervention Alters the Human Gut Microbiome but Not Fecal Short-Chain Fatty Acids.

DOI：
10.1128/msystems.00115-21
发表时间：
2021-03-16
期刊：
mSystems
影响因子：
6.4
作者：
Oliver A;Chase AB;Weihe C;Orchanian SB;Riedel SF;Hendrickson CL;Lay M;Sewall JM;Martiny JBH;Whiteson K
通讯作者：
Whiteson K

Global scale phylogeography of functional traits and microdiversity in Prochlorococcus.

DOI：
10.1038/s41396-023-01469-y
发表时间：
2023-10
期刊：
ISME JOURNAL
影响因子：
11
作者：
Ustick, Lucas J.;Larkin, Alyse A.;Martiny, Adam C.
通讯作者：
Martiny, Adam C.

Inhibiting parasite proliferation using a rationally designed anti-tubulin agent.

DOI：
10.15252/emmm.202013818
发表时间：
2021-11-08
期刊：
EMBO molecular medicine
影响因子：
11.1
作者：
Gaillard N;Sharma A;Abbaali I;Liu T;Shilliday F;Cook AD;Ehrhard V;Bangera M;Roberts AJ;Moores CA;Morrissette N;Steinmetz MO
通讯作者：
Steinmetz MO

Linking regional shifts in microbial genome adaptation with surface ocean biogeochemistry