Michigan State University VDL Vet-LIRN 2021

密歇根州立大学 VDL Vet-LIRN 2021

• 批准号: 10449684
• 负责人: KIMBERLY DODD
• 金额: $ 4.45万
• 依托单位: MICHIGAN STATE UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2021
• 资助国家: 美国
• 起止时间: 2021-09-06 至 2022-08-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10449684
• 关键词: Michigan; State; University; VDL; Vet

PAR-18-604 Vet-LIRN Network Capacity-Building Project Michigan State University Project Summary The Toxicology Section of the Michigan State University Veterinary Diagnostic Laboratory works in coordination with the FDA Vet-LIRN and the Food Emergency Response Network (FERN) to monitor, test, and report on chemical food contaminants in an effort to provide effective communication of laboratory findings to protect the nation’s food/feed supply. Testing of food products for chemical residues, including antimicrobial drugs and the naturally occurring fungal contaminant mycotoxins, are routinely performed by liquid chromatography tandem mass spectrometry. Newer methods for the detection of multiple drug residues in food products (Becker et al, 2004; Aguilera-Luiz et al, 2008; Heller et al, 2006, Tang et al, 2012) have been described for ultra-high performance liquid chromatography tandem mass spectrometers. The recent acquisition of a UPLC-MS/MS has greatly enhanced our capabilities and provides surge capacity with high throughput for Vet-LIRN and FERN- directed product testing. However, the current system LC-MS/MS system makes use of nitrogen cylinders instead of a continuous source of high purity gas. Additionally, sample preparation time is currently limited by the ability to remove solvent by gas evaporation. The acquisition of a nitrogen generator and a nitrogen evaporation unit will allow for increased sample capacity and throughput without interruption in analytical testing.

PAR-18-604 VET LIRN网络能力建设项目 密歇根州立大学 项目摘要 密歇根州立大学兽医诊断实验室的毒理学部分 借助FDA兽医LIRN和食品应急网络（FERN）来监视，测试和报告 化学食品污染物是为了提供有效的实验室发现以保护 国家的食品/饲料食品。 天然存在的真菌污染物霉菌毒素是常规的液相色谱串联 质谱法。 2004; Aguilera-Luiz等人，2008年； 表演型串联质谱仪。 极大地增强了我们的能力，并为吞吐量高吞吐量提供了激增的能力 - 导演产品测试。 另外，不是连续的纯净气体。 通过蒸发去除溶剂的能力。 蒸发单元柳树可用于疾病的样品容量和分析测试中中断。