Men Moving Forward: A Lifestyle Intervention for African American Prostate Cancer Survivors

男人向前迈进：对非裔美国前列腺癌​​幸存者的生活方式干预

• 批准号: 10310954
• 负责人: Melinda R Stolley
• 金额: $ 7.62万
• 依托单位: MEDICAL COLLEGE OF WISCONSIN
• 依托单位国家: 美国
• 财政年份: 2018
• 资助国家: 美国
• 起止时间: 2018-07-01 至 2023-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10310954
• 关键词: Address; African American; Attitude; Biological Markers; Body Composition; Cancer Survivor; Community Health; Doctor of Philosophy; Funding; Goals; Health; Health behavior; Incidence; Intervention; Interview; Life Style; Malignant Neoplasms; Malignant neoplasm of prostate; Mentors; Mentorship; Methodology; Not Hispanic or Latino; Parents; Population; Public Health; Quality of life; Reporting; Research; Research Design; Research Training; Self Efficacy; Social Network; Social support; Survivors; Target Populations; Training; Work; allostatic load; behavior change; behavior influence; biobehavior; cancer diagnosis; cancer health disparity; carcinogenesis; career; career development; comorbidity; diet and exercise; experience; health disparity; improved; interest; intervention program; lifestyle intervention; men; mortality; parent project; post intervention; programs; prostate cancer survivors; response; social

ABSTRACT This proposal seeks funding for a diversity supplement to provide Ms. Awoyinka, the candidate, with an intensive mentored research training and educational experience that will support the successful completion of her PhD and a subsequent career in cancer disparities research. Ms. Awoyinka will participate in a variety of research training, mentorship, and educational opportunities related to her research interests and objectives, and to the parent study, Men Moving Forward (MMF), a lifestyle intervention study designed with and for African American prostate cancer survivors (AAPCS) to improve health behaviors related to diet and exercise. Dr. Stolley, the PI will serve as her primary mentor, with additional mentorship provided by Dr. Young, who will offer support in qualitative methodology, and Dr. Knight who will offer training in biobehavioral mechanisms. The parent study seeks to examine the effects of participation in MMF on body composition, health behaviors, quality of life (QOL), and biomarkers related to comorbidities and carcinogenesis. The supplement will build on this work by exploring how social connection influences QOL, allostatic load and behavior change in men participating in the intervention. Specifically, the aims for this supplement are: 1) To describe social connections and their associations with QOL and self-efficacy among AAPC survivors pre- and post- intervention; 2) To explore the associations between social connections and allostatic load (specific markers to be determined through mentorship) at baseline; and 3) To gain a greater understanding of how social connections influence intervention engagement and behavior change using qualitative interviews. Prostate cancer (PC) is the most commonly diagnosed cancer among men, with highest incidence and lowest survival observed among African-Americans (AA). AA men with PC report poorer QOL relative to Non-Hispanic white men. Research suggests larger social networks and higher levels of social support are associated with declines in cancer mortality and improved quality of life in cancer survivors. Social networks can also influence behavioral norms and attitudes around health, and social support has been shown to enhance self-efficacy, a construct associated with positive behavior change. Little is known about the social connection of AAPCS and how it relates to QOL, allostatic load, or program engagement and response in this population. Despite documented disparities, there has been minimal work to date targeting this population. Improved understanding of how social connections influence AAPCS and their engagement in lifestyle intervention programs may help inform future research questions and identify opportunities to address disparities.

抽象的 该提案寻求多元化补充资金，为候选人阿沃因卡女士提供 强化指导的研究培训和教育经验将支持成功完成 她的博士学位以及随后从事癌症差异研究的职业生涯。 Awoyinka女士将参加各种 与她的研究兴趣和目标相关的研究培训、指导和教育机会， 以及家长研究“Men Moving Forward”（MMF），这是一项生活方式干预研究，旨在 非裔美国前列腺癌​​幸存者 (AAPCS) 改善与饮食和锻炼相关的健康行为。 PI 斯托利博士将担任她的主要导师，杨博士将提供额外指导。 提供定性方法方面的支持，奈特博士将提供生物行为机制方面的培训。 家长研究旨在探讨参与 MMF 对身体成分、健康行为、 生活质量（QOL）以及与合并症和致癌相关的生物标志物。该补充将建立在 这项工作通过探索社会联系如何影响男性的生活质量、稳态负荷和行为变化 参与干预。具体来说，本补充的目的是： 1) 描述社会 AAPC 幸存者前后的联系及其与生活质量和自我效能的关联 干涉; 2) 探索社会联系与稳态负荷之间的关联（特定标记 通过指导确定）在基线； 3) 更好地了解社会如何 通过定性访谈，联系会影响干预参与度和行为改变。前列腺 癌症（PC）是男性中最常诊断的癌症，发病率最高，生存率最低 在非裔美国人 (AA) 中观察到。患有 PC 的 AA 男性的生活质量相对于非西班牙裔白人较差 男人。研究表明，更大的社交网络和更高水平的社会支持与 癌症死亡率下降，癌症幸存者的生活质量提高。社交网络也会影响 围绕健康的行为规范和态度以及社会支持已被证明可以提高自我效能， 与积极行为改变相关的构建。人们对 AAPCS 和 AAPCS 的社会联系知之甚少。 它与该人群的生活质量、动态负荷或计划参与和反应有何关系。尽管 尽管有记录的差异，但迄今为止针对这一人群的工作很少。改进 了解社会关系如何影响 AAPCS 及其对生活方式干预的参与 计划可能有助于为未来的研究问题提供信息并确定解决差异的机会。