Development and preliminary examination of two brief personalized feedback interventions focused on lab-based and EMA alcohol cues to reduce hazardous young adult alcohol use

开发和初步检查两项简短的个性化反馈干预措施，重点是基于实验室和 EMA 的酒精提示，以减少危险的年轻人饮酒

• 批准号: 10229507
• 负责人: Anne Marie Fairlie
• 金额: $ 8.43万
• 依托单位: UNIVERSITY OF WASHINGTON
• 依托单位国家: 美国
• 财政年份: 2019
• 资助国家: 美国
• 起止时间: 2019-09-20 至 2024-08-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10229507
• 关键词: Address; Adolescent and Young Adult; Age; Age-Years; Alcohol consumption; Alcoholic Beverages; Alcoholic beverage heavy drinker; Alcohols; Attention; Awareness; Beer; Communities; Coping Skills; Cues; Development; Ecological momentary assessment; Emergency department visit; Environment; Exposure to; Feedback; Focus Groups; Heavy Drinking; Individual; Intervention; Lead; Learning; Motivation; National Institute on Alcohol Abuse and Alcoholism; Outcome; Participant; Pattern; Physiological; Pilot Projects; Prevalence; Procedures; Process; Randomized; Reporting; Research; Research Design; Research Support; Sampling; Series; Strategic Planning; Surveys; Testing; Thinking; acceptability and feasibility; age group; alcohol consequences; alcohol craving; alcohol cue; alcohol misuse; alcohol response; alcohol seeking behavior; alcohol use disorder; base; binge drinking; biological sex; brief alcohol intervention; brief intervention; coping; cost effective intervention; craving; cue reactivity; drinking; effective intervention; experience; experimental study; feasibility testing; fighting; follow-up; high intensity drinking; in vivo; intervention effect; learning strategy; novel; peer; reduced alcohol use; relating to nervous system; response; sexual assault; skills; university student; vehicular accident; young adult; young adult alcohol use

PROJECT SUMMARY/ABSTRACT Alcohol misuse and negative consequences remain prevalent among young adults (YAs) (Hingson et al., 2017; Schulenberg et al., 2018). Meta-analytic findings on the efficacy of brief alcohol interventions suggest that these effects may not be as strong as previously believed (Huh et al., 2015), highlighting the continuing need to develop effective interventions to reduce YA alcohol misuse. This application will develop and test two online personalized feedback interventions (PFIs) that focus on recognizing urges to drink in response to alcohol cues (e.g., beer bottle) as well as strategies for coping with urges. Alcohol cues evoke subjective craving and physiological and neural responses among drinkers (Reynolds & Monti, 2014; Schacht et al., 2013). Cue reactivity has been demonstrated in the natural environment among older adolescent and YA drinkers. On occasions when alcohol cues are present, YAs report stronger urges to drink, and on days with stronger urges to drink they report more alcohol consumption (Ramirez & Miranda, 2014). PFIs have not explicitly targeted cue reactivity, and many YAs may have limited awareness of this phenomenon. A cue-based PFI may reduce YA alcohol misuse by enhancing YAs’ awareness of their own personal cues that elicit alcohol-seeking behavior and by equipping YAs with skills for coping with urges. This current application will develop two online Cue Reactivity PFIs: (a) a lab-based Cue Reactivity PFI that summarizes cue reactivity from an in vivo cue reactivity session with exposure to preferred alcoholic beverages, and (b) a Cue Reactivity PFI that capitalizes on the utility of ecological momentary assessment (EMA) to capture alcohol cues as experienced in the natural environment. The EMA period includes 17 days of surveys (4x/day) to report cue exposure, craving, and alcohol outcomes. Both PFIs will focus on recognizing alcohol cues, understanding responses to cues, and acquiring coping skills. In Study 1 (Aim 1), a series of focus groups will be conducted with YA heavy drinkers (ages 18-24) to refine the procedures and interventions for a pilot study. Study 2 is a pilot study with a community sample of 200 YA heavy drinkers (ages 18-24) who report thinking about stopping or reducing their drinking. Participants are randomized to one of four conditions (n = 50 per group): (1) Lab- based Cue Reactivity PFI, (2) Lab-based assessment only control (AOC), (3) EMA-based Cue Reactivity PFI, or (4) EMA-based AOC. We will examine the feasibility and acceptability of the PFIs (Aim 2A), evaluate PFI effects on craving, drinking, and consequences at 2-week and 3-month follow-ups, relative to AOC conditions (Aims 2B-C), evaluate Lab-based versus EMA-based PFI effects on drinking outcomes (Aim 2D), and examine condition as a moderator of the association between craving and drinking at follow-up as well as explore moderators (e.g., biological sex) of intervention effects (Aim 2E). This research has great potential to inform advancements to personalized feedback interventions targeting YA alcohol use.

项目摘要/摘要 滥用酒精和负面后果在年轻人中仍然普遍存在（YAS）（Hingson等，，，。 2017; Schulenberg等，2018）。关于短暂酒精干预效率的荟萃分析结果表明 这些影响可能不如以前认为的那样强（Huh等，2015），强调了持续的 需要制定有效的干预措施以减少滥用酒精。此应用程序将开发和测试两个 在线个性化反馈干预措施（PFI），专注于认识到要饮酒的冲动 酒精提示（例如啤酒瓶）以及应对冲动的策略。酒精提示唤起主观 饮酒者的渴望以及身体和神经反应（Reynolds＆Monti，2014年； Schacht等， 2013）。在较旧的青少年和YA的自然环境中已证明了提示反应性 饮酒者。 Yas有时会报告饮酒，并报告要喝酒的冲动更强烈 他们报告更多的饮酒率（Ramirez＆Miranda，2014年）。 PFI没有 明确针对的提示反应性，许多YA可能对这种现象的认识有限。基于提示的 PFI可能会通过增强Yas对引起的个人线索的认识来减少YA酒精滥用 寻求酒精的行为，并为YA提供应对冲动的技能。当前的应用程序将 开发两个在线提示反应性PFI：（a）基于实验室的提示反应性PFI总结了提示反应性 从体内提示反应性会话中，暴露于首选酒精卧室，（b）提示反应性 PFI利用生态瞬时评估（EMA）捕获酒精线索的效用 在自然环境中经验丰富。 EMA期间包括17天的调查（每天4倍）以报告提示 暴露，渴望和酒精结果。两个PFI都将专注于识别酒精提示，理解 对线索的响应，并负责应对技巧。在研究1（AIM 1）中，将进行一系列焦点小组 与YA饮酒者（18-24岁）一起，以完善试点研究的程序和干预措施。研究2是 试点研究，由200名重量饮酒者（18-24岁）组成的社区样本，他们报告了关于停止的考虑 或减少饮酒。参与者被随机分为四个条件之一（每组n = 50）：（1）实验室 - 基于提示反应性PFI，（2）基于实验室的评估对照（AOC），（3）基于EMA的提示反应性PFI， 或（4）基于EMA的AOC。我们将检查PFI的可行性和可接受性（AIM 2A），评估PFI 相对于AOC条件，对2周和3个月的随访对渴望，饮酒和后果的影响 （AIMS 2B-C），评估基于实验室的PFI对饮酒结果的影响（AIM 2D），并检查 条件是渴望和随访时渴望和饮酒之间的关联的调节器以及探索 干预效果的主持人（例如生物性别）（AIM 2E）。这项研究有很大的潜力来告知 针对YA饮酒的个性化反馈干预措施的进步。