Vaper to Vaper (V2V): A Multimodal Mobile Peer Driven Intervention to Support Adolescents in Quitting Vaping

Vaper to Vaper (V2V)：支持青少年戒烟的多模式移动同伴驱动干预

基本信息

批准号：
10402794
负责人：
LORI PBERT
金额：
$ 37.69万
依托单位：
UNIV OF MASSACHUSETTS MED SCH WORCESTER
依托单位国家：
美国
项目类别：
财政年份：
2021
资助国家：
美国
起止时间：
2021-05-15 至 2024-04-30
项目状态：
已结题

来源：
https://reporter.nih.gov/project-details/10402794
关键词：
Abstinence Academy Address Adolescent Adult American Attention Behavior Therapy Cigarette Smoker Cotinine Development Electronic cigarette Epidemic Evidence based intervention Feasibility Studies Foundations Goals Individual Integrative Therapy Intention Intervention Learning Life Style Memory Monitor Motivation Nicotine Nicotine Dependence Outcome Patient Recruitments Pediatrics Prevalence Prevention Program Development Protocols documentation Randomized Readiness Research Risk Schools Smoker Smoking Surgeon Symptoms Technology Testing Text Messaging Time Tobacco Training Work acceptability and feasibility adolescent brain development asynchronous communication base cigarette smoking combustible cigarette craving design e-cigarette cessation efficacy testing electronic cigarette use electronic cigarette user evidence base experience feasibility research follow-up high risk high school improved improved outcome innovation mobile computing multimodality novel novel strategies participant retention peer peer coaching peer influence pilot test preference programs recruit response satisfaction success tailored messaging tool usability vaper vaping

项目摘要

7. Project Summary/Abstract The FDA and the US Surgeon General call the increasing use of e-cigarettes among U.S. adolescents an epidemic, with e-cigarette use exceeding combustible cigarette use. The high amounts of nicotine in e-cigarettes harm adolescent brain development, impacting learning, memory, and attention. Adolescent e-cigarette users also are at higher risk than non-users of transitioning to traditional cigarettes. While prevention is important, evidence-based interventions to engage and help adolescent e-cigarette users quit are critically needed. Key challenges include adolescents perceiving e-cigarette use to be of low risk resulting in a low intention to quit, and the major influence of peers in e-cigarette use. Given there currently are no evidence-based cessation interventions to assist adolescent e-cigarette users in quitting, as suggested by the American Academy of Pediatrics and FDA, we propose to develop Vaper-to-Vaper (V2V), a multi-modal mobile peer driven intervention, based on lessons learned in our prior tobacco intervention work. Peer-driven interventions have been found to successfully improve smoking outcomes in adolescents, and we have had success in developing peer-driven interventions for low motivated adult smokers. We therefore will adapt these approaches for adolescent e- cigarette users. V2V’s goal will be to engage, educate, motivate, and facilitate the adolescent in using strategies to manage cravings and successfully quit. The V2V components will include: Peer Messaging (tailored messages pushed via texting), Peer Coaching (asynchronous communications with trained coaches via texting), and Gamification (using game design to motivate participation). Adapting these tools to the unique needs of adolescent e-cigarette users will further extend these tools into novel directions. For Aim 1 we will convene a peer advisory panel of 20 adolescent e-cigarette users to participate in a qualitative assessment and further development of V2V components. In Aim 2 we will evaluate the feasibility of the research protocols and the feasibility and acceptability of the V2V intervention in a pilot feasibility study with eighty adolescent e-cigarette users from 4 high schools (schools randomized to either V2V intervention or control) recruited and followed for 6 months. We hypothesize being able to recruit 80 adolescents (20/school, 40 per study condition) and that >85% will be retained in each study condition at 6-month follow-up (Aim 2A). For Aim 2b we will monitor V2V engagement (e.g., number of V2V texting quizzes completed, peer coaching interactions, peer videos viewed) and assess acceptability of and satisfaction with the program. For Aim 2C we hypothesize that the intervention will be associated with greater cotinine-validated 7-day point prevalence vaping abstinence rates, lower time to first quit attempt, and less amount of e-cigarette use compared to control at 6-month follow-up. This Stage I project, adapting an existing intervention and feasibility/pilot testing, will provide the necessary materials and information to proceed to a subsequent large-scale Stage III R01 trial to test the efficacy of the V2V intervention in supporting adolescent e-cigarette users in quitting.

7. 项目总结/摘要 FDA 和美国卫生局局长称美国青少年越来越多地使用电子烟电子烟的使用量超过了可燃香烟的使用量，电子烟中的尼古丁含量很高。损害青少年大脑发育，影响青少年电子烟使用者的学习、记忆和注意力。虽然预防很重要，但与不吸食传统香烟的人相比，他们面临的风险也更高。迫切需要基于证据的干预措施来吸引和帮助青少年电子烟使用者戒烟。挑战包括青少年认为使用电子烟风险较低，导致戒烟意愿较低，以及同龄人对电子烟使用的主要影响，因为目前还没有基于证据的戒烟。美国科学院建议采取干预措施帮助青少年电子烟使用者戒烟儿科和 FDA，我们建议开发 Vaper-to-Vaper (V2V)，一种多模式移动同伴驱动的干预措施，根据我们之前的烟草干预工作中吸取的经验教训，我们发现同伴驱动的干预措施可以成功地改善了青少年的吸烟结果，并且我们已经成功地开发了同伴驱动的因此，我们将针对青少年吸烟者采取这些方法。 V2V 的目标是吸引、教育、激励和促进青少年使用策略。管理渴望并成功戒烟 V2V 组件将包括：同伴消息传递（定制消息）。通过短信推送）、同伴辅导（通过短信与训练有素的教练进行异步通信），以及游戏化（使用游戏设计来激励参与）。青少年电子烟用户将进一步将这些工具扩展到新的方向。对于目标 1，我们将召开一次会议。由 20 名青少年电子烟使用者组成的同行咨询小组参与定性评估并进一步在目标 2 中，我们将评估研究协议和 V2V 组件的可行性。在针对 80 支青少年电子烟的试点可行性研究中，V2V 干预的可行性和可接受性来自 4 所高中（学校随机接受 V2V 干预或控制）的用户被招募并跟踪 6 个月以来，我们已经招募了 80 名青少年（每所学校 20 名，每种研究条件 40 名）。在 6 个月的随访中，>85% 将保留在每种研究条件下（目标 2A），我们将监测 V2V。参与度（例如，完成的 V2V 短信测验数量、同伴辅导互动、观看的同伴视频）并评估该计划的可接受性和满意度对于目标 2C，我们采取了干预措施。将与更高的经可替宁验证的 7 天点流行率、更短的吸电子烟戒断率相关在第一阶段的 6 个月随访中，与对照组相比，首次尝试戒烟，电子烟的使用量较少。项目，调整现有的干预措施和可行性/试点测试，将提供必要的材料和信息以进行后续大规模 III 期 R01 试验，以测试 V2V 干预的功效支持青少年电子烟使用者戒烟。

项目成果

期刊论文数量（1）

专著数量（0）

科研奖励数量（0）

会议论文数量（0）

专利数量（0）

Vaping Cessation Support Recommendations from Adolescents Who Vape: A Qualitative Study.

电子烟青少年的戒烟支持建议：一项定性研究。

DOI：
10.21203/rs.3.rs-4077848/v1
发表时间：
2024
期刊：
Research square
影响因子：
0
作者：
Pbert,Lori;Dubé,CatherineE;Nagawa,CatherineS;Simone,DanteP;Wijesundara,Jessica;Sadasivam,Rajani
通讯作者：
Sadasivam,Rajani