Research Training in Gastroenterology and Hepatology

胃肠病学和肝病学研究培训

• 批准号: 10397620
• 负责人: JEAN-PIERRE RAUFMAN
• 金额: $ 44.78万
• 依托单位: UNIVERSITY OF MARYLAND BALTIMORE
• 依托单位国家: 美国
• 财政年份: 2005
• 资助国家: 美国
• 起止时间: 2005-07-01 至 2025-06-30
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10397620
• 关键词: Gastroenterology; Hepatology; Research Training

This competitive renewal application for T32 DK067872, Research Training in Gastroenterology and Hepatology, submitted on behalf of the University of Maryland, Baltimore (UMB) requests 5 years of support for 3 predoctoral and 4 postdoctoral (MD, PhD, MD/PhD) trainees. Program goals are to seek and prepare talented trainees for research and/or leadership careers in academia, government, or industry by offering an integrated, inter- disciplinary curriculum that emphasizes basic or clinical & translational science training in one of three major substantive areas: (1) gastrointestinal mucosal biology & signaling, (2) gut microbiome, immunology & genetics, and (3) hepatobiliary disorders. UMB entities represented by faculty mentors with robust federal funding portfolios cut across schools, departments, and organized research centers and institutes to include the Schools of Medicine (Departments of Medicine, Pediatrics, Surgery, Epidemiology & Public Health, Microbiology & Immunology, Biochemistry & Molecular Biology) and Pharmacy (Department of Pharmaceutical Sciences), the Center for Vaccine Development & Global Health, and the Institute for Genome Sciences. Comprehensive training opportunities allow predoctoral trainees to obtain PhD or MD/PhD degrees and postdoctoral trainees to earn MS, MPH or PhD degrees. Under the supervision of expert mentors, this training program is designed to enable trainees to develop hypotheses, design and perform basic or clinical research to test these hypotheses, become expert in at least one substantive area relevant to digestive or liver diseases, develop oral and written presentation skills, master the principles of responsible conduct of research, and prepare for transition to careers focused on the study of the biology and pathobiology of the GI tract and hepatobiliary system. Basic and clinical & translational science training in three focus areas (GI Mucosal Biology & Signaling; Gut Microbiome, Immunology & Genetics; Hepatobiliary Disorders), is directed by accomplished, highly productive experienced mentors who interact both within and amongst research tracks. Since its inception in 2005, this T32 program has been highly successful; all training slots were consistently filled, trainee retention was 100%, and productivity as measured by publications, awarding of advanced degrees, and career outcomes has been exceptional. All predoctoral trainees who completed training qualified for the PhD degree and nearly all MD postdoctoral trainees either have or will be awarded advanced degrees (MS, MPH, or PhD). This T32 program remains extraordinarily diverse, fulfilling a societal need to redress underrepresentation in biomedical research and academia; two-thirds of our trainees are women and one-fifth are Latino or African American. Former trainees obtained academic faculty appointments or perform research for federal agencies (NIH and FDA) or industry, competed successfully for federal funding, and attained leadership positions in academia. Notably, by attracting talented trainees and investigators from other disciplines to basic and patient-centered digestive diseases and liver research, this T32 program adds great value to the UMB clinical, educational and scientific community.

T32 DK067872 的竞争性更新申请，胃肠病学和肝病学研究培训， 代表马里兰大学巴尔的摩分校 (UMB) 提交，请求为 3 名博士前人员提供 5 年支持 博士后（MD、PhD、MD/PhD）培训生4名。计划目标是寻找并培养有才华的学员 通过提供综合的、跨领域的研究和/或领导职业生涯，在学术界、政府或工业界 强调三个专业之一的基础或临床和转化科学培训的学科课程 实质性领域：(1) 胃肠粘膜生物学和信号传导，(2) 肠道微生物组、免疫学和遗传学， (3)肝胆疾病。 UMB 实体由拥有雄厚联邦资金的教师导师代表 作品集跨越学校、院系以及有组织的研究中心和研究所，其中包括学校 医学系（医学系、儿科系、外科系、流行病学与公共卫生系、微生物学系和 免疫学、生物化学和分子生物学）和药学（药物科学系）， 疫苗开发与全球健康中心以及基因组科学研究所。综合的 培训机会使博士前学员能够获得博士学位或医学博士/博士学位，博士后学员能够获得 获得 MS、MPH 或博士学位。本次培训计划在专家导师的指导下，旨在 使学员能够提出假设，设计并进行基础或临床研究来测试这些假设， 成为至少一个与消化或肝脏疾病相关的实质性领域的专家，发展口头和书面能力 演讲技巧，掌握负责任的研究行为原则，并为职业过渡做好准备 专注于胃肠道和肝胆系统的生物学和病理学研究。基础和临床 三个重点领域的转化科学培训（胃肠粘膜生物学和信号传导；肠道微生物组， 免疫学与遗传学；肝胆疾病），由卓有成效、经验丰富的专家指导 在研究轨道内和研究轨道之间互动的导师。自 2005 年启动以来，T32 计划已 非常成功；所有培训名额均已满，学员保留率为 100%，生产率为 以出版物、高级学位授予和职业成果来衡量，该大学的表现非常出色。全部 完成培训的博士前学员获得博士学位，几乎所有博士后学员 已经或将被授予高级学位（硕士、公共卫生硕士或博士学位）。这个T32程序仍然非常出色 多样化，满足纠正生物医学研究和学术界代表性不足的社会需求；三分之二 我们的学员中有女性，五分之一是拉丁裔或非裔美国人。前学员获得学术 为联邦机构（NIH 和 FDA）或行业任命教师或进行研究，并成功竞争 获得联邦资助，并在学术界获得领导职位。值得注意的是，通过吸引有才华的学员和 来自其他学科的研究人员到基础和以患者为中心的消化疾病和肝脏研究，这个 T32 该计划为 UMB 临床、教育和科学界增添了巨大价值。