Training Program for Applied Research and Development in Genomic Medicine

基因组医学应用研究与开发培训计划

• 批准号: 10224446
• 负责人: JULIE A. JOHNSON
• 金额: $ 7.98万
• 依托单位: UNIVERSITY OF FLORIDA
• 依托单位国家: 美国
• 财政年份: 2020
• 资助国家: 美国
• 起止时间: 2020-09-15 至 2022-12-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10224446
• 关键词: Applied Research; Genomic medicine; Training Programs; research and development; Applied Research; Genomic medicine; Training Programs; research and development

Abstract Healthcare professionals, scientists, and the public are embracing the potential advances in healthcare that are possible, and in some cases being delivered now, through approaches that employ genomic and other personal information to improve care. To ensure these expectations become reality requires a highly qualified cadre of clinician-scientists, scientists and clinicians working collaboratively to advance discoveries and implementation in genomic medicine. We propose a new post-doctoral genomic medicine training program called “Program for Applied Research and Development in Genomic Medicine or PARADIGM”. This training program for MDs, PharmDs, other clinical specialists at the doctoral level, and PhDs is based on four premises: Genomic medicine: 1. will be led primarily by doctorally-trained clinicians and a team approach is essential. 2. needs clinical translational scientists in with core competencies in translational science, and specialized knowledge in genomic medicine. 3. will require leaders, and this program will foster development of leadership and professionalism. 4. will improve lives through scientific leaders in academia, healthcare, the private sector, governmental regulatory science and policy, among other sectors. To train individuals to meet these needs, PARADIGM will provide up to 4 post-doctoral scholars a multi-year, integrated, multidisciplinary program to prepare them for a career in genomic medicine. Broadly, the program is comprised of four major components: 1) a Didactic component of required and optional coursework; 2) a Mentored Research component involving a defined research project under the mentorship of an accomplished genomic medicine scientist and clinician; 3) a Clinical Genomic Medicine component that integrates them into the genomic medicine clinical practice setting; and 4) a Professional Development component including experiential training through presenting at national meetings, participating in grant and budget reviews, mentoring students and other activities. The mosaic of training experiences across these four components will be tailored according to the previous experiences, educational needs and research interests of the trainee, but will be concentrated in three cores of expertise at UF: pharmacogenomics, cancer genomics, and disease susceptibility genetics/genomics. We will rely on 36 highly talented, collaborative, multidisciplinary mentors to execute the program. PARADIGM will undergo continuous evaluation and quality improvement to ensure long-term success of the trainees. Upon program completion, each trainee will be expected to possess knowledge and skills that will enable them to manage the challenges of evidence generation and clinical use of genomic medicine.

抽象的 医疗保健专业人员，科学家和公众正在接受医疗保健的潜在进步 这是可能的，在某些情况下，通过员工基因组的方法现在交付 以及其他个人信息以改善护理。确保这些期望成为现实需要 临床科学家，科学家和临床医生合作合作 基因组医学中的提前发现和实施。我们提出了新的博士后 基因组医学培训计划称为“用于应用研究和开发计划 基因组医学或范式”。 在博士学位上，博士学位基于四个前提：基因组医学：1。 受过博士训练的临床医生和团队方法至关重要。 2。需要临床翻译科学家 具有转化科学领域的核心能力，以及基因组医学方面的专业知识。 3。 将需要领导者，该计划将促进领导力和专业精神的发展。 4 通过学术界，医疗保健，私营部门，政府的科学领袖改善生活 监管科学与政策以及其他部门。训练个人满足这些需求， 范式将提供多达4个博士后学者，这是一个多年的，综合的，多学科的 计划为他们准备基因组医学职业。从广义上讲，该程序已完成四个 主要组成部分：1）所需课程和可选课程的教学成分； 2）一个指导 研究组成部分涉及一个已定义的研究项目 基因组医学科学家和临床； 3）整合的临床基因组医学成分 他们进入基因组医学临床实践环境； 4）专业发展 组成部分包括通过在国家会议上展示，参加格兰特的经验丰富的培训 以及预算评论，心理学生和其他活动。训练经验的马赛克 在这四个组件中，将根据以前的经验来量身定制教育需求 和学员的研究兴趣，但将集中在UF的三个专业知识中： 药物基因组学，癌症基因组学和疾病易感性遗传学/基因组学。我们将依靠 36高才华，合作的，多学科的导师来执行该计划。范式会 进行持续的评估和质量改进，以确保培训的长期成功。 计划完成后，每个学员都将拥有知识和技能 使他们能够管理基因组医学的证据产生和临床使用的挑战。