BIDIRECTIONAL TRAINING TO ENHANCE CANCER RESEARCH CAPACITY IN AFRICA

加强非洲癌症研究能力的双向培训

• 批准号: 10223596
• 负责人: TIMOTHY R REBBECK
• 金额: $ 27.37万
• 依托单位: DANA-FARBER CANCER INST
• 依托单位国家: 美国
• 财政年份: 2021
• 资助国家: 美国
• 起止时间: 2021-05-05 至 2026-04-30
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10223596
• 关键词: Africa; Africa South of the Sahara; African; Bilateral; Cancer Burden; Educational Curriculum; Effectiveness; Extramural Activities; Funding; Goals; Grant; Health; Individual; Knowledge; Lead; Leadership; Malignant Neoplasms; Malignant neoplasm of esophagus; Mentors; Oncology; Outcome; Participant; Principal Investigator; Program Development; Prostate carcinoma; Public Health; Research; Research Personnel; Research Project Grants; Risk; Training; Training Programs; Training and Education; anticancer research; base; cancer risk; career; career development; experience; falls; improved; improved outcome; knowledge base; malignant breast neoplasm; men; mortality; programs; recruit; skills

PROJECT SUMMARY/ABSTRACT Cancer mortality rates are projected to more than double in Sub-Saharan Africa (SSA) in the next two decades. This public health crisis requires that a knowledge base be developed to better understand and act on the growing cancer burden in SSA. We propose a training program that will maximize the rigor of cancer research in SSA by training researchers to develop strategic and operational capacity that will generate new knowledge about the determinants of cancer risk and outcomes and improve effectiveness of strategies for reducing risk and improve outcomes. The overarching goals of this training program are to 1) Develop and disseminate best practices to enable the highest quality cancer research in Africa; 2) Teach fundamental skills to those who conduct research in Africa; and 3) Create a cadre of individuals who can lead and support cancer research in SSA. Our training program proposes the following specific aims: 1) Develop and implement an educational and career development program that will maximize the rigor of research being conducted in SSA; 2) Recruit and train individuals who can build sustainable careers in cancer research; 3) Assess the impact of this training program on the career outcomes of trainees and participants. Trainees will fall into two groups. First, we propose a Principal Investigator (PI) Track for doctoral level investigators who will be trained to demonstrate leadership in independent and collaborative research. Participants in the PI Track will become proficient in research oversight and governance and build the skills and a scientific project focus toward independent extramural grant funding. Second, a Project Management (PM) Track will be implemented to support the conduct of research. Participants in the PM Track will be qualified to support a variety of research projects within SSA health and regulatory settings. Training will involve bilateral interactions between mentors and trainees in both SSA and the US who will partner to develop and implement best research practices. The training program will build on highly successful existing research networks in SSA: The African Breast Cancer Study (ABCS), The African Esophageal Cancer Consortum (AFRECC), The African Research Group in Oncology (ARGO), and the Men of African Descent and Carcinoma of the Prostate (MADCaP) network. Building on mentors and research capacity of these networks, the proposed program will provide a core research curriculum known as the PROject Management Oversight Training and Education in AFRICA (PROMOTE-AFRICA) framework as well as project-based (for the PI Track) or practicum-based (for the PM track) activities as well as other educational experiences to individuals seeking careers as independent cancer researchers or project managers.

项目概要/摘要 预计未来两年撒哈拉以南非洲 (SSA) 的癌症死亡率将增加一倍以上 几十年。这场公共卫生危机需要建立一个知识库，以便更好地理解和采取行动 SSA 日益增长的癌症负担。我们提出了一个培训计划，将最大限度地提高癌症的严格性 通过培训研究人员发展战略和运营能力来开展SSA研究，从而产生新的 了解癌症风险和结果的决定因素，并提高癌症策略的有效性 降低风险并改善结果。该培训计划的总体目标是 1) 开发和 传播最佳实践，以实现非洲最高质量的癌症研究； 2）传授基本技能 那些在非洲进行研究的人； 3) 创建一支能够领导和支持癌​​症的骨干队伍 SSA 的研究。我们的培训计划提出了以下具体目标： 1) 制定并实施 教育和职业发展计划，将最大限度地提高 SSA 正在进行的研究的严谨性； 2）招募和培训能够在癌症研究领域建立可持续职业生涯的个人； 3) 评估影响 该培训计划关注学员和参与者的职业成果。受训者将分为两组。 首先，我们为博士级研究人员提出了一个首席研究员（PI）轨道，他们将接受培训 展示在独立和合作研究中的领导力。 PI Track 的参与者将成为 精通研究监督和治理，并培养技能和科学项目重点 独立的校外拨款。其次，将实施项目管理（PM）轨道 支持研究的进行。 PM Track 的参与者将有资格支持各种研究 SSA 健康和监管环境内的项目。培训将涉及导师之间的双边互动 以及 SSA 和美国的实习生，他们将合作开发和实施最佳研究实践。这 培训计划将以 SSA 现有的非常成功的研究网络为基础：非洲乳腺癌 研究 (ABCS)、非洲食管癌联盟 (AFRECC)、非洲研究小组 肿瘤学 (ARGO) 以及非洲人后裔和前列腺癌 (MADCaP) 网络。 基于这些网络的导师和研究能力，拟议的计划将提供核心 研究课程被称为非洲项目管理监督培训和教育 (PROMOTE-AFRICA) 框架以及基于项目的（针对 PI 轨道）或基于实践的（针对 PM 追踪）活动以及对寻求独立癌症职业的个人的其他教育经历 研究人员或项目经理。