Couples Managing Early-Stage Dementia: Mutual Influences on Daily Stress, Self-Care, and Well-Being

应对早期痴呆症的夫妇：对日常压力、自我护理和幸福感的相互影响

• 批准号: 10220718
• 负责人: Courtney A. Polenick
• 金额: $ 12.85万
• 依托单位: UNIVERSITY OF MICHIGAN AT ANN ARBOR
• 依托单位国家: 美国
• 财政年份: 2018
• 资助国家: 美国
• 起止时间: 2018-08-01 至 2023-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10220718
• 关键词: Activities of Daily Living; Adult; Affect; Aging; Alzheimer' s disease related dementia; Area; Biological; Buffers; Caregiver Burden; Caregivers; Caring; Cognition; Cognitive; Communities; Complex; Couples; Data; Dementia; Early Diagnosis; Early Intervention; Elderly; Family; Family Caregiver; Foundations; Gender; Goals; Growth; Health; Hospitalization; Hydrocortisone; Incidence; Individual; Intervention; K-Series Research Career Programs; Knowledge; Life; Link; Literature; Measures; Medical; Mental Depression; Mental Health; Mentors; Mentorship; Methods; Modeling; Moods; Morbidity - disease rate; Outcome; Pathway interactions; Patient Self-Report; Pattern; Perception; Personal Satisfaction; Persons; Prevalence; Process; Public Health; Reporting; Research; Research Personnel; Resources; Risk; Risk Factors; Role; Self Care; Self Efficacy; Services; Severities; Shapes; Sleep; Source; Spouse Caregiver; Spouses; Stress; Testing; Time; Training; Translating; Vulnerable Populations; Wife; Woman; adverse outcome; alpha-amylase; biopsychosocial; career; caregiving; clinical care; coping; dementia care; design; disability; early awareness; experience; functional disability; gender difference; improved; men; negative affect; novel; preservation; prevent; programs; protective factors; psychosocial; satisfaction; skills; stressor; therapy design

PROJECT SUMMARY Alzheimer's disease and related dementias (ADRD) are an increasing public health concern, currently affecting over 5 million US adults and approximately 3 million of their spousal caregivers. This project extends research on caregiver stress and health outcomes to consider the relations among daily stress, self-care, and well-being within couples managing the early stages of ADRD, a potentially critical time window to preserve each care partner's well-being. There is growing recognition for the value of early intervention and self-care strategies among persons with ADRD and their caregivers, reflecting the urgency for greater awareness of early mutual influences within care dyads that inform interventions to maintain their optimal health and functioning. The proposed mentored career development award combines a rigorous program of research, mentorship, and didactics to facilitate the candidate's growth toward an overall career goal of becoming an independent investigator focused on informing the design of interventions for aging couples with complex care needs including ADRD to improve both partners' well-being. The training aims will assist the candidate in acquiring: 1) grounded knowledge of clinical care and educational needs for persons with ADRD and their spouses that will provide a foundation for translating research findings into targeted interventions; 2) specialized skills in the assessment, analysis, and interpretation of biomeasures of stress that are potential mechanisms linking the ADRD care situation to health and well-being; and 3) proficiency in the use of intensive repeated measures designs that will generate novel information on proximal risk and protective factors for poor outcomes within care dyads. The training aims seek to further develop the candidate's expertise as an interdisciplinary researcher in the area of later-life spousal caregiving relationships and align closely with the research aims to: 1) examine the links among own and partner reports of daily stressors, self-care, and well- being within care dyads; 2) determine the links among own and partner reports of daily stressors and biomeasures of stress within care dyads; and 3) identify which individuals and couples are more or less resilient to stress by evaluating how psychosocial resources (self-efficacy, dyadic coping, and marital quality) within dyads moderate the associations among daily stress, self-care, and well-being. The findings will yield key knowledge of everyday mutual influences on positive and negative outcomes among couples managing early-stage ADRD, informing targeted interventions to promote the well-being of both care partners.

项目摘要 阿尔茨海默氏病和相关痴呆症（ADRD）是一个日益严重的公共卫生问题，目前 影响超过500万的美国成年人及其配偶照料者。该项目扩展 护理人员压力和健康结果的研究，以考虑日常压力，自我保健和 在管理ADRD的早期阶段的夫妻中的幸福感，这是一个潜在的关键时间窗口 每个护理伙伴的福祉。早期干预和自我保健的价值越来越认识到 ADRD及其护理人员的人之间的策略，反映出更加认识 护理二元组中的早期相互影响，以告知干预措施以保持其最佳健康和 功能。拟议的指导职业发展奖结合了严格的研究计划， 指导和教学法促进候选人的成长，以成为成为一个整体职业目标 独立研究者致力于告知与复杂护理的老年夫妇的干预措施的设计 包括ADRD在内的需求，以改善两个合作伙伴的福祉。培训目标将有助于候选人 获取：1）基于ADRD及其患者的临床护理和教育需求的知识 将为将研究结果转化为有针对性干预措施的配偶； 2） 评估，分析和解释潜在的压力生物测定方面的专业技能 将ADRD护理状况与健康和福祉联系起来的机制； 3）熟练使用密集型 重复的措施设计将产生有关近端风险和保护因素的新信息 护理中的结果。培训目标旨在进一步发展候选人的专业知识 跨学科研究人员在后期的配偶照顾关系领域，并与 研究目的是：1）检查自己和合作伙伴之间的联系，以及每日压力源，自我保健以及良好的链接 在护理中的二元组； 2）确定每日压力源和合作伙伴报告之间的链接以及 护理二元组中压力的生物测定； 3）确定哪些个人和夫妇或多或少是 通过评估心理社会资源（自我效能，二元应对和婚姻质量）如何通过评估压力的弹性 在二元组中，每日压力，自我保健和福祉之间的关联。调查结果将产生 对夫妻管理的积极和负面结果的日常相互影响的关键知识 早期的ADRD，告知有针对性的干预措施，以促进两个护理伙伴的福祉。