Core A: Administrative/Clinical/Bioinformatics Core

核心 A：行政/临床/生物信息学核心

• 批准号: 10206250
• 负责人: Stanley L Hazen
• 金额: $ 21.74万
• 依托单位: CLEVELAND CLINIC LERNER COM-CWRU
• 依托单位国家: 美国
• 财政年份: 2019
• 资助国家: 美国
• 起止时间: 2019-09-01 至 2024-07-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10206250
• 关键词: Advisory Committees; Arts; Bioinformatics; Biometry; Cardiometabolic Disease; Cardiovascular Diseases; Charge; Clinic; Clinical; Clinical Data; Committee Members; Communication; Contracts; Databases; Deposition; Development; Diet; Disease Progression; Ensure; Environment; Fostering; Goals; Health; Human; Human Resources; Hybrids; Informatics; Institution; Lead; Link; Manuscripts; Metabolic Diseases; Mission; Monitor; Office of Administrative Management; Participant; Pathway interactions; Patient Care; Personal Satisfaction; Photography; Physiological; Predisposition; Preparation; PubMed; Research Activity; Research Personnel; Resource Sharing; Resources; Sampling; Schedule; Services; Statistical Data Interpretation; United States National Institutes of Health; Universities; Visit; clinical database; clinical material; cluster computing; data access; design; gut microbiome; gut microbiota; instrument; meetings; member; microbial community; microbial composition; programs; response; statistics

Administrative/Clinical/Bioinformatics Core (Core A): Abstract The overall goals of the Administrative/Clinical/Bioinformatics Core are to provide fiscal, administrative, clinical material and data access, bioinformatic and statistics support to each Project and Core within this Program Project. The Administrative/Clinical/Bioinformatics Core has both administrative and scientific missions that will support the goals and personnel of this PPG. This core will be responsible for supporting all administrative efforts for the PPG, centralizing access to de-identified Clinical samples and related clinical databases, and coordinating biostatistics and informatics analyses for PPG members, including assistance in microbial composition analyses for the Projects within the PPG. Administrative duties include coordination of all NIH interactions, including assembly and preparation of this application, coordination of annual non-competitive renewal related submissions, and all other NIH related interactions. This core will also function to unify and coordinate activities amongst the Program Project participants, including organization of monthly meetings, and all internal and external reviews. Another major function of this core will be to foster and coordinate collaborative research activities within the PPG through use of shared clinical resources with clinical database, bioinformatics and statistics support. Finally, this core will help coordinate microbial community composition analyses across the PPG. Thus, this core will facilitate the organizational and administrative management of the Program, orchestrating communication within the Program, monitoring of progress in the Projects, ensuring effective use of the shared resource cores, and provide key clinical, database, bioinformatics and statistical support.

行政/临床/生物信息学核心（核心 A）：摘要 行政/临床/生物信息学核心的总体目标是提供财政、 为每个项目提供行政、临床材料和数据访问、生物信息和统计支持 和本计划项目的核心。 行政/临床/生物信息学核心具有行政和科学使命，将支持 该 PPG 的目标和人员。该核心将负责支持所有行政工作 PPG，集中访问去识别化的临床样本和相关临床数据库，并协调 为 PPG 成员提供生物统计学和信息学分析，包括微生物组成方面的帮助 对 PPG 内的项目进行分析。行政职责包括协调所有 NIH 互动， 包括组装和准备此应用程序，协调年度非竞争性续订相关事宜 提交以及所有其他 NIH 相关的互动。该核心还将发挥统一和协调活动的作用 在计划项目参与者中，包括每月组织会议以及所有内部和 外部评论。该核心的另一个主要职能是促进和协调合作研究 通过使用与临床数据库、生物信息学和技术共享的临床资源，在 PPG 内开展活动 统计支持。最后，该核心将有助于协调整个区域的微生物群落组成分析 PPG。因此，该核心将促进该计划的组织和行政管理， 协调计划内的沟通，监控项目进展，确保有效使用 共享资源核心，并提供关键的临床、数据库、生物信息学和统计支持。