Yoga for women with breast cancer undergoing radiotherapy

适合接受放射治疗的乳腺癌女性的瑜伽

• 批准号: 8635304
• 负责人: Lorenzo Cohen
• 金额: $ 71.77万
• 依托单位: UNIVERSITY OF TX MD ANDERSON CAN CTR
• 依托单位国家: 美国
• 财政年份: 2010
• 资助国家: 美国
• 起止时间: 2010-04-01 至 2016-03-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8635304
• 关键词: Acute; Address; Adherence; Adjuvant; Adverse effects; Aftercare; Anxiety; Appointment; Attention; Behavior; Breast Cancer Treatment; Breathing; Cancer Patient; Cessation of life; Cognitive; Combined Modality Therapy; Control Groups; Cost Effectiveness Analysis; Counseling; Diagnosis; Disease Progression; Distress; Emotional; Fatigue; Fright; Health; Health Care Costs; Home environment; Hospitals; Hydrocortisone; Individual; Intervention; Life; Lung; Maintenance; Malignant Neoplasms; Measures; Mediating; Meditation; Mental Depression; Mental Health; Morbidity - disease rate; Movement; Operative Surgical Procedures; Outcome; Participant; Patients; Periodicity; Phase III Clinical Trials; Physical Function; Physical activity; Physiological; Posture; Process; Productivity; Psychological Side Effects; Quality of life; Radiation; Radiation therapy; Randomized; Recovery; Recurrence; Relaxation; Relaxation Techniques; Reporting; Research; Schedule; Science; Skin; Sleep disturbances; Social support; Source; Spirituality; Stress; Stretching; Symptoms; Techniques; Telephone; Time; Trauma; Treatment Efficacy; Treatment Protocols; Woman; Work; Yoga; arm; behavior change; body-mind; cancer therapy; chemotherapy; coping; cost effectiveness; economic outcome; experience; follow-up; group intervention; improved; indexing; intervention effect; malignant breast neoplasm; preference; programs; psychologic; social; social model; standard of care; stress management; stressor; treatment as usual; treatment effect; treatment planning; visual imagery

Cancer and its treatment are associated with considerable distress, impaired quality of life (QOL), poor mental health, and reduced physical function. This is particularly true for women with breast cancer who receive multimodal treatment over an extended period of time. Many women undergo surgery and chemotherapy, which are often followed by radiotherapy. It is important to develop programs that can help ameliorate the treatment-related morbidity that accumulates over time for women with breast cancer. Furthermore, given the stressful time demands posed by radiotherapy treatment (patients typically receive treatment 5-days per week for 6 weeks) it is crucial that programs be easily incorporated into the treatment schedule. Research suggests that stress-reduction programs tailored to the cancer setting may help patients cope with the acute effects of treatment and improve QOL after treatment. Yoga, an ancient Indian science, incorporates stress-reduction techniques including regulated breathing, visual imagery, meditation, and various gentle stretching postures. Yoga may be particularly useful for women with breast cancer after surgery and while undergoing radiation treatment because of the stress management and relaxation techniques and the gentle stretching that should facilitate recovery. Preliminary studies found yoga is useful for women with breast cancer undergoing radiotherapy. Integrating a yoga program into the treatment regimen of women undergoing radiotherapy for breast cancer makes participation in the program easy and compliance has been high. We will determine the efficacy of implementing a yoga program for patients with breast cancer as an adjuvant to their radiotherapy. Patients with breast cancer who are undergoing radiotherapy will be randomly assigned to one of three groups: a yoga group, a stretching/relaxation group, or a waitlist control group. Participants in the two intervention groups will attend sessions 3 days/week throughout their 6-week radiotherapy schedule. Measures will be obtained prior to randomization, midway through radiotherapy, during the last week of radiotherapy, and 1 and 3, 6 and 12 months after the end of radiotherapy. We will examine indices of QOL, fatigue, sleep disturbances, mental health, cost- effectiveness analysis, work and/or home productivity, and cortisol rhythmicity. We hypothesize that the yoga program will help facilitate recovery and alleviate the physiological and psychological side effects experienced by patients who are currently receiving radiotherapy.

癌症及其治疗与相当大的痛苦和生活质量受损有关 （生活质量）、心理健康状况不佳以及身体机能下降。对于女性来说尤其如此 长期接受多模式治疗的乳腺癌患者。许多 女性接受手术和化疗，通常随后进行放疗。这是 制定有助于改善治疗相关发病率的计划非常重要 患有乳腺癌的女性会随着时间的推移而积累。此外，考虑到时间紧张 放射治疗提出的要求（患者通常每周接受 5 天的治疗） 为期 6 周）重要的是要将方案轻松纳入治疗计划中。 研究表明，针对癌症情况量身定制的减压计划可能会有所帮助 患者应对治疗的急性影响并改善治疗后的生活质量。瑜伽，一个 古印度科学融合了减压技术，包括调节呼吸、 视觉意象、冥想和各种温和的伸展姿势。瑜伽可能特别 对于手术后和接受放射治疗期间的乳腺癌女性有用 由于压力管理和放松技巧以及温和的伸展运动 应有利于恢复。初步研究发现瑜伽对患有乳腺癌的女性有用 正在接受放射治疗。将瑜伽项目纳入女性治疗方案中 接受乳腺癌放射治疗使参与该计划变得容易且 合规性一直很高。我们将确定实施瑜伽计划的功效 乳腺癌患者作为放射治疗的辅助疗法。乳腺癌患者 正在接受放射治疗的人将被随机分配到三组之一：瑜伽组 组、伸展/放松组或候补对照组。两人的参与者 干预小组将在为期 6 周的放射治疗期间每周参加 3 天的会议 日程。将在随机化之前、放射治疗中途获得测量值， 放疗最后一周，以及放疗结束后1、3、6、12个月 放射治疗。我们将检查生活质量、疲劳、睡眠障碍、心理健康、成本等指标 有效性分析、工作和/或家庭生产力以及皮质醇节律。我们假设 瑜伽课程将有助于促进康复并缓解生理和 目前正在接受放射治疗的患者所经历的心理副作用。