Prenatal Social Connection and Disruption During the COVID-19 Pandemic: Effects on Maternal and Infant Health

COVID-19 大流行期间的产前社交联系和中断：对母婴健康的影响

• 批准号: 10187191
• 负责人: Darby E. Saxbe
• 金额: $ 36.12万
• 依托单位: UNIVERSITY OF SOUTHERN CALIFORNIA
• 依托单位国家: 美国
• 财政年份: 2021
• 资助国家: 美国
• 起止时间: 2021-06-01 至 2026-01-31
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10187191
• 关键词: Affect; Age; Anxiety; Anxiety Disorders; Apgar Score; Behavior; Behavioral; Birth; Birth Weight; Buffers; COVID-19; COVID-19 pandemic; Child; Child Health; Child Rearing; Childbirth; Communities; Coronavirus; Data; Data Reporting; Data Set; Development; Disease; Distress; Economics; Enrollment; Extended Family; Family health status; Fathers; Feeling; Fetal Development; Foundations; Fright; Funding; Geographic Locations; Gestational Age; Guidelines; Hair; Health; Height; Home; Hospitals; Hydrocortisone; Incidence; Infant; Infant Development; Infant Health; Infection; Knowledge; Link; Location; Loneliness; Long-Term Effects; Low Birth Weight Infant; Maternal Health; Measures; Mental Depression; Mental Health; Modeling; Mood Disorders; Mothers; National Institute of Child Health and Human Development; Natural experiment; Neurosecretory Systems; Outcome; Parents; Participant; Patient Self-Report; Personal Satisfaction; Persons; Population; Postpartum Period; Pregnancy; Pregnant Women; Premature Birth; Prenatal care; Readiness; Recovery; Reporting; Research; Risk; Risk Factors; Sampling; Schools; Shapes; Social Behavior; Social Distance; Social support; Source; Strategic Planning; Stress; Temperament; Testing; United States; Woman; anxiety symptoms; biopsychosocial factor; cohort; depressive symptoms; experience; follow-up; health economics; healthy pregnancy; in utero; indexing; infant temperament; insight; neurodevelopment; neuroimaging; pandemic disease; perceived stress; postpartum outcome; prenatal; prenatal stress; protective factors; psychological distress; recruit; resilience; social; social factors; stress management; stress resilience; stressor; Affect; Age; Anxiety; Anxiety Disorders; Apgar Score; Behavior; Behavioral; Birth; Birth Weight; Buffers; COVID-19; COVID-19 pandemic; Child; Child Health; Child Rearing; Childbirth; Communities; Coronavirus; Data; Data Reporting; Data Set; Development; Disease; Distress; Economics; Enrollment; Extended Family; Family health status; Fathers; Feeling; Fetal Development; Foundations; Fright; Funding; Geographic Locations; Gestational Age; Guidelines; Hair; Health; Height; Home; Hospitals; Hydrocortisone; Incidence; Infant; Infant Development; Infant Health; Infection; Knowledge; Link; Location; Loneliness; Long-Term Effects; Low Birth Weight Infant; Maternal Health; Measures; Mental Depression; Mental Health; Modeling; Mood Disorders; Mothers; National Institute of Child Health and Human Development; Natural experiment; Neurosecretory Systems; Outcome; Parents; Participant; Patient Self-Report; Personal Satisfaction; Persons; Population; Postpartum Period; Pregnancy; Pregnant Women; Premature Birth; Prenatal care; Readiness; Recovery; Reporting; Research; Risk; Risk Factors; Sampling; Schools; Shapes; Social Behavior; Social Distance; Social support; Source; Strategic Planning; Stress; Temperament; Testing; United States; Woman; anxiety symptoms; biopsychosocial factor; cohort; depressive symptoms; experience; follow-up; health economics; healthy pregnancy; in utero; indexing; infant temperament; insight; neurodevelopment; neuroimaging; pandemic disease; perceived stress; postpartum outcome; prenatal; prenatal stress; protective factors; psychological distress; recruit; resilience; social; social factors; stress management; stress resilience; stressor

PROJECT SUMMARY The COVID-19 pandemic has had sweeping effects on pregnant women and their partners. The need to adhere to social distancing guidelines has altered the social connectedness of expectant parents, with effects on stress, loneliness, reduced access to in- person prenatal care, and childbirth support. Social support during pregnancy is known to buffer stress and predict better postpartum outcomes for both new parents and their infants. For example, greater prenatal support has been linked with decreased risk of parental postpartum mood and anxiety disorders, lower incidence of preterm birth and low birth weight, calmer infant temperament, and healthier infant development. Given this evidence, pandemic-induced changes to social connectedness during pregnancy may have long-term effects for new parents and their children. The current proposal leverages the unique natural experiment of the COVID-19 pandemic to examine the maternal and infant health effects of social connectedness among pregnant women and their partners. The CHIRP (Coronavirus, Health, Isolation and Resilience in Pregnancy) study launched in spring 2020 and has enrolled 710 expectant parents who reported on their feelings of social connectedness and support during pregnancy. We will follow up with this cohort three, six, and 12 months after the birth of their child. In addition to collecting self-report data, we will gather hospital birth charts to measure gestational outcomes, and hair cortisol to measure neuroendocrine stress exposure. We also plan to use geocoding to model the social, economic, and health impacts of the pandemic and explore how these impacts shape postpartum outcomes. Our lab has already collected data from another cohort of 200 expectant parents recruited during pregnancy and followed over the transition to parenthood, constituting a pre-pandemic comparison sample with the same measures and timing. We will also conduct a five-year follow-up with children from our pre-pandemic dataset that will incorporate behavioral and neuroimaging measures of neurodevelopment. Our pilot data indicates significantly higher ratings of psychological distress and lower ratings of social support among expectant parents affected by the COVID-19 pandemic. We expect that this project will make important contributions to the study of stress and resilience during pregnancy and its long-term effects on both maternal and infant well-being.

项目摘要 COVID-19大流行对孕妇及其她人及其 合作伙伴。遵守社会疏远准则的需求改变了社会 预期父母的联系，对压力，孤独感的影响，降低了进入 人产前护理和分娩支持。众所周知，怀孕期间的社会支持 缓冲压力和预测新父母及其婴儿的产后结果更好。 例如，更多的产前支持与父母的风险降低有关 产后情绪和焦虑症，早产的发病率较低和低出生 体重，婴儿气质和更健康的婴儿发育。有了这个证据， 大流行引起的对怀孕期间社会联系的变化可能具有长期 对新父母及其子女的影响。 当前的提案利用了Covid-19的独特自然实验 大流行检查社会联系对母亲和婴儿的健康影响 孕妇及其伴侣。 chirp（冠状病毒，健康，孤立和 怀孕的韧性）研究于2020年春季启动，已注册710名。 在报告社交联系和支持期间的父母 怀孕。我们将在他们出生后三个，六和12个月后跟进这个队列 孩子。除了收集自我报告数据外，我们还将收集医院的出生图以衡量 妊娠结局和头发皮质醇，以测量神经内分泌胁迫暴露。我们也是 计划使用地理编码来建模大流行的社会，经济和健康影响 并探索这些影响如何影响产后结果。我们的实验室已经收集了 来自怀孕期间招募的另一个同类的另一个同伙的数据，随之而来 在过渡到父母的过渡之后，构成了学前比较样本 相同的措施和时机。我们还将与我们的孩子进行五年的随访 学前数据集将结合行为和神经影像学措施 神经发育。 我们的飞行员数据表明​​，心理困扰和较低的评级明显更高 受到19日大流行影响的准父母之间社会支持的评级。我们 预计该项目将为压力和韧性研究做出重要贡献 在怀孕期间及其对孕产妇和婴儿幸福感的长期影响。