Research Education Component (REC)

研究教育部分（REC）

• 批准号: 9922634
• 负责人: Hussein N Yassine
• 金额: $ 10.26万
• 依托单位: UNIVERSITY OF SOUTHERN CALIFORNIA
• 依托单位国家: 美国
• 财政年份: 2020
• 资助国家: 美国
• 起止时间: 2020-09-01 至 2025-02-28
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/9922634
• 关键词: Affect; Age; Age-associated memory impairment; Aging; Alzheimer' s Disease; Alzheimer' s disease related dementia; Alzheimer' s disease therapeutic; Area; Award; Biometry; Blood Vessels; Body Weight decreased; California; Clinical Trials; Cognitive; Collaborations; Communities; County; Data; Decision Making; Demography; Diabetes Mellitus; Discipline; Dyslipidemias; Economics; Education; Elderly; Environment; Ethnic group; Exercise; Exposure to; Faculty; Family; Fellowship; Funding; Gerontology; Goals; Grant; Health; Health Policy; Healthcare; Hypertension; Image; Incidence; Institutes; Interdisciplinary Study; Intervention; Investigator-Initiated Research; Life Style; Los Angeles; Medicine; Mentors; Mentorship; Metabolic; Metabolism; Minority; Mission; Monitor; Multimodal Imaging; Neuropsychology; Obesity; Population; Population Research; Postdoctoral Fellow; Psychometrics; Publishing; Research; Research Institute; Research Personnel; Research Project Grants; Resources; Risk; Risk Factors; Scientist; Secure; Social Work; Sociology; Targeted Research; Testing; Tissue Sample; Training; Training Programs; Underrepresented Minority; Universities; academic program; age related; base; brain health; career; career development; clinical center; cohort; computer science; dementia risk; design; education research; ethnic minority population; experience; health care economics; improved; medical schools; multidisciplinary; programs; recruit; simulation; social; success; symposium; translational genomics; vascular risk factor

Abstract: Research Education Component (REC) The mission of the University of Southern California (USC) Alzheimer’s disease research center (ADRC) Research Education Core (REC) is to direct the scientific careers of scientists from diverse disciplines into a career in Alzheimer’s disease and related dementias (ADRD) research in general, and an emphasis on age-associated vascular/metabolic processes that affects ADRD risk in the Latinx population in Los Angeles County. Obesity, diabetes, dyslipidemia and hypertension have been found at disproportionally high rates in Latinx communities. These metabolic and vascular risk factors have also been associated with an increased AD incidence and age-related cognitive decline. However, very few interventions have been designed to target the risk factors specific to these populations. We propose to center our REC training program on areas that are focused on Latinx elderly brain health by leveraging existing research programs at USC focused on AD risk in ethnic minorities. To achieve our aims, we have partnered with several ADRD and Aging training programs that actively engage scientists from under-represented ethnic groups that we aim to integrate into our program. We have three Specific Aims. First, support ADRC scientists through multidisciplinary training program, pilot funding and an annual symposium. Second, support the career development of up to three post-doctoral investigators from under-represented minority researchers who have shown remarkable professional promise for a 2-year post-doctoral fellowship sponsored by the USC provost office. Third, monitor the progress of ADRC scientists during the period of the award as well as through their early career milestones (e.g., receipt of an independent grant). ADRC scientist alumni will be supported in continued involvement in activities that support and improve both their career options and the experience of the next cohort of pilot grantees.

摘要：研究教育部分（REC） 南加州大学 (USC) 阿尔茨海默病研究中心的使命 (ADRC) 研究教育核心 (REC) 旨在指导科学家的科学生涯 从事阿尔茨海默病和相关痴呆症 (ADRD) 研究的不同学科 总体而言，并强调影响 ADRD 的与年龄相关的血管/代谢过程 洛杉矶县拉丁裔人口的肥胖、糖尿病、血脂异常和肥胖风险。 拉丁裔社区的高血压发病率异常高。 代谢和血管危险因素也与 AD 发病率增加有关 然而，针对这一问题的干预措施却很少。 我们建议将 REC 培训计划集中在这些人群特有的风险因素上。 通过利用现有的研究项目，重点关注拉丁裔老年人大脑健康的领域 南加州大学专注于少数族裔的 AD 风险。为了实现我们的目标，我们与多家机构合作。 ADRD 和老龄化培训计划积极吸引来自代表性不足的种族的科学家 我们希望将这些群体纳入我们的计划中，我们有三个具体目标：第一，支持。 ADRC 科学家通过多学科培训计划、试点资金和年度 二是支持最多3名博士后科研人员的职业发展。 来自代表性不足的少数族裔研究人员，他们表现出了卓越的专业前景 获得南加州大学教务长办公室资助的为期 2 年的博士后奖学金 第三，监督。 ADRC 科学家在获奖期间以及早期职业生涯中取得的进步 ADRC 科学家校友将在以下方面获得支持： 继续参与支持和改善他们的职业选择和职业发展的活动 下一批试点受资助者的经验。