2020 Food Allergy Gordon Research Conference and Gordon Research Seminar

2020年食物过敏戈登研究会议暨戈登研究研讨会

基本信息

批准号：
9914389
负责人：
WAYNE G SHREFFLER
金额：
$ 1万
依托单位：
GORDON RESEARCH CONFERENCES
依托单位国家：
美国
项目类别：
财政年份：
2019
资助国家：
美国
起止时间：
2019-12-12 至 2020-11-30
项目状态：
已结题

来源：
https://reporter.nih.gov/project-details/9914389
关键词：
Address Allergic Disease Antigens Applied Research Area Asthma Atopic Dermatitis Basic Science Biological Cells Child Clinic Clinical Sciences Collaborations Communities Complex Dangerousness Diet Discipline Disease Environment Fertilization Food Hypersensitivity Fostering Future Global Awareness Health Immersion Immune Immune system Immunity Immunology Lead Life Mentors Mentorship Minority Mucous Membrane Nutritional Oncology Pathway interactions Postdoctoral Fellow Prevention strategy Research Research Personnel Research Support Role Scientist Therapeutic Trials Thinking Time Translational Research Woman Work career data exchange design experience frontier gastrointestinal system graduate student human disease innovation insight interest meetings multidisciplinary neurodevelopment neurosensory novel phase III trial success symposium

项目摘要

Food allergy research is rapidly evolving and increasingly multidisciplinary, as global awareness of this complex, multifactorial, life-threatening disease accelerates. The first ever phase III trials of therapeutics have recently been completed, and like other allergic disease, biologics have the potential to reshape treatment approaches in the clinic over the coming next few years. However, very fundamental questions about the mechanisms of immunity to dietary antigens in health and disease remain unanswered and in some cases are just beginning to be systematically addressed. Better understanding mechanisms such as how innate and adaptive immune cells interact with neurosensory pathways to sense diet and regulate the digestive and immune systems will very likely lead to new more rational and effective prevention strategies and treatments. Better understanding the role of Th2 immunity in neurodevelopment and oncology may provide important insights for safe application of rapidly emerging and potentially transformational biologics to the problems of food allergy as well as atopic dermatitis, asthma and other allergic diseases. The overall aim for the 2020 Food Allergy Gordon Conference is to enhance the quality and quantity of food allergy research. We are committed to attracting top researchers in the field, and fully integrating trainees, early career investigators, and especially women and minority researchers, to better reflect and ultimately increase the true diversity of this emerging field of high and increasing impact.

随着全球意识，食物过敏研究正在迅速发展和越来越多学科在这种复杂，多因素，威胁生命的疾病中，加速了。有史以来第一次III期试验最近已经完成了治疗剂，并且像其他过敏性疾病一样，生物制剂也有未来几年，在诊所重塑治疗方法的潜力。但是，关于对饮食抗原免疫机制的非常基本的问题健康和疾病仍未得到答复，在某些情况下才刚刚开始系统地解决。更好地理解诸如先天和适应性的机制免疫细胞与神经感觉途径相互作用，以感知饮食并调节消化率和免疫系统很可能会导致新的更理性和有效的预防策略和治疗。更好地了解Th2免疫在神经发育中的作用和肿瘤学可能会为安全应用快速应用和潜在地提供重要见解转化生物制剂，用于食物过敏以及特应性皮炎，哮喘和其他过敏性疾病。 2020年食品过敏戈登会议的总体目标是提高食物过敏研究的质量和数量。我们致力于吸引顶级该领域的研究人员，以及充分整合受训者，早期职业调查人员，尤其是妇女和少数派研究人员，以更好地反映并最终增加这个新兴领域的高影响力和越来越多的影响。