Pediatric Pathology Translational Research

儿科病理学转化研究

• 批准号: 8463608
• 负责人: MARK D FLEMING
• 金额: $ 25.54万
• 依托单位: BOSTON CHILDREN'S HOSPITAL
• 依托单位国家: 美国
• 财政年份: 2012
• 资助国家: 美国
• 起止时间: 2012-05-01 至 2018-04-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8463608
• 关键词: Childhood; Pathology; Translational Research

DESCRIPTION (provided by applicant): This is a revised application for a Ruth L. Kirschstein Institutional National Research Service Award (NRSA/T32) developed for post-doctoral research training for MD, MD/PhD, and PhD fellows preparing for a career as an independent investigator in translational pediatric pathology research. There is a particular focus on research into the pathophysiology of disorders of the heart, lung or blood that are particularly prevalent i children. The Program proposal includes formal didactic training in translational medicine, human subjects research, the ethical conduct of research, and innovative technologies such as genomics and proteomics as well as a mentored research experience in an academically rich environment that is supported by numerous educational and career development resources provided by Children's Hospital Boston and the Harvard Catalyst Clinical Translational Sciences Center (CTSC). The Training Program centers around the Department of Pathology at Children's Hospital Boston and involves its research faculty supported by a select group of translational investigators from other Departments at Children's Hospital Boston, the Brigham and Women's Hospital, Harvard Medical School, and the Broad Institute. To enhance the collaborative, translational pathology nature of the Program, trainees are also required to draw upon the experience of the clinical pediatric pathology faculty and are encouraged to utilize the substantial frozen and formalin-fixed, paraffin-embedded tissue resources of the Department for their studies. Above all, the overriding goal of the Program is to endow the next generation of translational pediatric pathologists with the skills to contribute to innovative diagnostics and treatment of pediatric diseases.

描述（由申请人提供）：这是 Ruth L. Kirschstein 机构国家研究服务奖 (NRSA/T32) 的修订申请，旨在为医学博士、医学博士/博士和博士研究员进行博士后研究培训，为他们的职业生涯做准备转化儿科病理学研究的独立研究者。特别注重研究 研究儿童中特别常见的心脏、肺或血液疾病的病理生理学。该计划提案包括转化医学、人类受试者研究、研究的道德行为以及基因组学和蛋白质组学等创新技术方面的正式教学培训，以及在丰富的学术环境中获得指导的研究经验，并得到众多教育和职业发展的支持波士顿儿童医院和哈佛催化剂临床转化科学中心 (CTSC) 提供的资源。该培训计划以波士顿儿童医院病理科为中心，其研究人员得到了来自波士顿儿童医院、布莱根妇女医院、哈佛医学院和博德研究所其他科室的一组精选转化研究人员的支持。为了增强该计划的协作、转化病理学性质，还要求学员借鉴临床儿科病理学教师的经验，并鼓励他们利用该部门大量的冷冻和福尔马林固定、石蜡包埋的组织资源来进行他们的研究。研究。最重要的是，该计划的首要目标是赋予下一代转化儿科病理学家技能，为儿科疾病的创新诊断和治疗做出贡献。