Northwestern University Lead Academic Participating Site

西北大学主导学术参与网站

• 批准号: 9901493
• 负责人: AL B BENSON
• 金额: $ 51.52万
• 依托单位: NORTHWESTERN UNIVERSITY AT CHICAGO
• 依托单位国家: 美国
• 财政年份: 2019
• 资助国家: 美国
• 起止时间: 2019-04-01 至 2025-02-28
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/9901493
• 关键词: Adult; Advanced Malignant Neoplasm; Advisory Committees; American College of Radiology Imaging Network; Ancillary Study; Basic Science; Cancer Center; Cancer Intervention; Cancer Patient; Clinical; Clinical Research; Clinical Trials; Collaborations; Comprehensive Cancer Center; Core Facility; Core Grant; Development; Discipline; Disease; Eastern Cooperative Oncology Group; Enrollment; Ensure; Faculty; Financial Support; Goals; Health; Home environment; Infrastructure; Institution; International; Intervention Studies; Intervention Trial; Laboratories; Lead; Leadership; Malignant Neoplasms; Mentors; Mentorship; Organization administrative structures; Outcome; Outcome Measure; Pathology; Patient imaging; Patients; Phase; Population Sciences; Publications; Rare Diseases; Recording of previous events; Reporting; Research; Research Infrastructure; Research Personnel; Resource Sharing; Resources; Role; Science; Scientific Advances and Accomplishments; Site; Southwest Oncology Group; Structure; Time; Tissue imaging; Tissues; Translations; Universities; Validation; base; bench to bedside; cancer therapy; career; clinical care; clinical imaging; data quality; data warehouse; design; experience; follow-up; imaging modality; improved; inter-institutional; medical schools; member; multimodality; named group; programs; quantitative imaging; ranpirnase; recruit; senior faculty; standard of care; success; tissue resource

PROJECT SUMMARY/ABSTRACT The Robert H. Lurie Comprehensive Cancer Center of Northwestern University (LCC) has a long history of NCTN participation with ECOG membership since 1973. Currently, the LCC infrastructure supports participation in clinical trials and ancillary studies through the ECOG- ACRIN, SWOG, Alliance, NRG and COG. Recognized for accrual, participation, and high-level of data quality, the LCC has been selected by the NCTN leadership to participate in the High Performing Site Initiative (HPSI) in 2015, 2016 and 2017 to support our infrastructure and to enable continued participation in NCTN trials. The Lurie Cancer Center's overall accrual to NCTN studies during 3/1/14 - 8/31/17 was 400, 383 of which were accrued to Interventional trials. In addition, LCC members are heavily involved in the leadership of NCTN activities. From 3/1/14 and 8/31/16, LCC members have served as Network Group committee and subcommittee members (74), committee and subcommittee chairs and co-chairs (19), study chairs and co-chairs (22), and members of various NCI Steering Committees or Task Forces (10). In addition, the extensive number of Network Group publications (65) and abstracts (70) authored or co-authored by the investigators during the last 3 years alone further demonstrates our leadership role within the NCTN. Through demonstration of significant scientific accomplishments and new initiatives, recent recruitment of accomplished senior faculty and productive junior faculty, comprehensive and integrated infrastructure for oversight of cancer-related clinical trials including the establishment of a NCTN Oversight Committee, emphasis on mentoring of junior faculty, significant financial support of NCTN activities and a highly experienced and productive leadership which has been continuously active within the NCTN, the LCC has proved that it has the governance, organizational capabilities and commitment, as well as the general expertise of the senior leadership team to support this LAPS application.

项目摘要/摘要 西北大学（LCC）的罗伯特·H·卢里（Robert H. Lurie）综合癌症中心有很长的 自1973年以来，NCTN参与ECOG会员的历史。目前，LCC 基础设施支持通过ECOG参与临床试验和辅助研究 Acrin，Swog，Alliance，NRG和COG。因应计，参与和高级认可 数据质量，NCTN领导已选择了LCC参加高级 2015年，2016年和2017年执行现场倡议（HPSI），以支持我们的基础架构和 启用继续参加NCTN试验。 Lurie癌症中心对NCTN的总体应计 14年3月1日至8/31/17期间的研究为400，其中383项进行了介入。 此外，LCC成员大量参与了NCTN活动的领导。从14年3月1日起 和8/31/16，LCC成员曾担任网络小组委员会和小组委员会 成员（74），委员会和小组委员会椅子和联合主席（19），学习椅和联合主席 （22），以及各种NCI转向委员会或工作队的成员（10）。另外， 大量网络组出版物（65）和摘要（70）撰写或合着 仅在过去的三年中，调查人员进一步证明了我们在 NCTN。 通过展示重大的科学成就和新倡议，最近 招募有成就的高级教师和富有成效的初级教师， 用于监督癌症相关临床试验的综合基础设施 NCTN监督委员会的重点是指导初级教师，大量财务 支持NCTN活动以及经验丰富且富有成效的领导 LCC在NCTN中不断活跃，证明了它具有治理， 组织能力和承诺，以及高级的一般专业知识 领导团队支持此圈申请。