Recruitment Innovations to Enhance Diversity in AD Research

招聘创新增强 AD 研究的多样性

基本信息

批准号：
9535812
负责人：
JENNIFER Hagerty LINGLER
金额：
$ 60.38万
依托单位：
UNIVERSITY OF PITTSBURGH AT PITTSBURGH
依托单位国家：
美国
项目类别：
财政年份：
2017
资助国家：
美国
起止时间：
2017-08-01 至 2022-04-30
项目状态：
已结题

来源：
https://reporter.nih.gov/project-details/9535812
关键词：
Address Adult African American Alzheimer&apos s Disease Awareness Basic Science Biological Blood Caregiver support Caucasians Cities Clinical Clinical Research Clinical Sciences Cognitive Communication Communities Community Outreach Complex Diagnosis Disease Elderly Enrollment Ensure Environment Ethnic Origin Ethnography Event Family Funding Goals Grant Health Household Impaired cognition Income Institutes Interview Minority Groups Modeling Multimedia Neighborhoods Not Hispanic or Latino Persons Public Health Registries Reporting Research Research Design Research Infrastructure Research Project Grants Resources Sampling Science Series Support Groups Tissues Translational Research Underrepresented Minority Underrepresented Populations Universities Vulnerable Populations Work base cohort combat dementia care ethnic diversity ethnic minority population experience health disparity health economics innovation member middle age novel strategies outreach primary outcome programs racial diversity racial minority recruit relative cost research study response social social media success

项目摘要

ABSTRACT Despite experiencing Alzheimer’s-related health problems at a disproportionate rate, African Americans are consistently and severely underrepresented in Alzheimer’s disease and related disorders (ADRD) research projects. Insufficient enrollment of African Americans in this line of research is a nationally-recognized problem. This is highly concerning not only because of the need for unbiased, representative samples in basic science and clinical research, but also because involving persons from underrepresented minority groups is crucial to advancing our understanding of, and ultimately combating, health disparities. In response to PAR-15- 349 “Health Disparities and Alzheimer’s Disease”, we propose to develop and evaluate a novel strategy that uses a storytelling campaign to enhance recruitment of African American adults into research at the University of Pittsburgh Alzheimer Disease Research Center. In Specific Aim 1, we will build on our promising pilot work to refine and evaluate community members’ acceptance of a storytelling strategy for communicating Alzheimer’s-related research participation experiences of African Americans in mid and late life. The storytelling strategy will highlight African Americans’ research participation narratives, as derived from a series of ethnographic interviews and told using short videos. In Specific Aim 2, we will evaluate the effect of this storytelling strategy on recruitment of African Americans into ADRD research. Videos developed in Aim 1 will be incorporated into all existing ADRC recruitment efforts, ranging from community events to social media strategies. The primary outcome for Aim 2 will be the proportion of African Americans recruited to the ADRC Clinical Core over an 18 month period, with the preceding 18 month period serving as the comparator. Specific Aim 3 will use path analysis modeling to explore the mechanisms by which a storytelling strategy increases enrollment of African Americans into ADRD research in general, and into a specific study designed to address health disparities. Realizing the goals of this study will increase racial and ethnic diversity in ADRD research at a leading NIA-funded ADRC and ultimately, help to reduce cognitive health disparities amongst African Americans. Findings from this study will directly inform best practices for increasing diversity within the national AD Centers network, with significant implications for a range of underrepresented populations. Furthermore, these findings will also have applications in other disease contexts in which scientific progress is constrained by insufficient recruitment of persons from underrepresented racial and ethnic minority groups.

抽象的尽管以不成比例的情况遇到了与阿尔茨海默氏症相关的健康问题，但非裔美国人是在阿尔茨海默氏病和相关疾病（ADRD）研究中始终如一，严重代表性不足项目。非洲裔美国人在这一研究中的入学人数不足是一项全国认可的问题。这不仅是因为需要基本的公正，代表性样本，因此高度关注科学和临床研究，这也是因为参与代表性不足的少数群体的人是对于促进我们对健康差异的理解并最终战斗至关重要。响应15杆 349“健康差异和阿尔茨海默氏病”，我们建议制定和评估一种新型策略，利用讲故事的运动来增强非裔美国人成年人的招募匹兹堡阿尔茨海默氏病研究中心。在特定目标1中，我们将以我们的诺言飞行员工作为基础完善和评估社区成员对交流的讲故事策略的接受阿尔茨海默氏症与非洲裔美国人在中期和后期的研究经历。这讲故事的策略将重点介绍非裔美国人的研究参与叙事，从一个系列中得出民族志访谈，并使用简短的视频讲述。在特定的目标2中，我们将评估这一点的效果关于招募非裔美国人进入ADRD研究的讲故事策略。 AIM 1中开发的视频将将其纳入所有现有的ADRC招聘工作中，从社区活动到社交媒体策略。目标2的主要结果是招募到ADRC的非裔美国人的比例在18个月内的临床核心，其之前18个月作为比较器。具体的 AIM 3将使用路径分析建模来探索讲故事策略增加的机制一般而言，非裔美国人进入ADRD研究，并参与一项旨在解决的特定研究健康差异。实现这项研究的目标将增加ADRD研究的种族和种族多样性由NIA资助的领先的ADRC，最终有助于减少非洲的认知健康差异美国人。这项研究的发现将直接为增加多样性的最佳实践提供信息国家广告中心网络，对一系列代表性不足的人群产生了重大影响。此外，这些发现还将在其他疾病的情况下应用，科学进步是受到代表性不足的赛车和少数民族群体的招募不足的限制。