Accompanying HIV-positive adolescents through the transition into adult care: a feasibility study

陪伴艾滋病毒阳性青少年过渡到成人护理：可行性研究

• 批准号: 9886206
• 负责人: Molly Forrest Franke
• 金额: $ 19.42万
• 依托单位: HARVARD MEDICAL SCHOOL
• 依托单位国家: 美国
• 财政年份: 2019
• 资助国家: 美国
• 起止时间: 2019-03-05 至 2022-02-28
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/9886206
• 关键词: Acquired Immunodeficiency Syndrome; Address; Adherence; Adolescence; Adolescent; Adult; Behavioral; CD4 Lymphocyte Count; Caring; Cessation of life; Child; Childhood; Clinical; Communities; Community Health Aides; Complex; Consent; Coping Skills; Data; Data Collection; Development; Disclosure; Disease Management; Emotional; Ensure; Evaluation; Face; Feasibility Studies; Future; HIV; HIV Seropositivity; Health; Health Services; Health Status; Intervention; Intervention Studies; Intervention Trial; Legal; Logistics; Measures; Medical; Mental Health; Neurocognitive; Newly Diagnosed; Outcome; Outcome Assessment; Patient Care; Patients; Performance; Perinatal; Peru; Pharmaceutical Preparations; Pilot Projects; Population; Pregnancy; Procedures; Prospective Studies; Provider; Reporting; Research Personnel; Sample Size; Schools; Social support; Time; Training; Viral Load result; antiretroviral therapy; barrier to care; base; behavioral outcome; cohort; design; follow-up; improved; medication compliance; multidisciplinary; programs; psychosocial; recruit; sexual debut; social exclusion; social stigma; support network; supportive environment; therapy design; tool; transgender women; transmission process; young men who have sex with men

PROJECT SUMMARY/ABSTRACT The transition to adult HIV care is often accompanied by reduced medication adherence, retention, HIV viral load suppression and CD4 cell counts; however, little is known about which interventions might be most effective in supporting adolescents undergoing this care transition. We will conduct a feasibility study for a community-based accompaniment intervention, delivered by community health workers, that is designed to improve health outcomes among adolescents transitioning to adult care in urban Peru. We will (1) conduct an intervention pilot to determine the feasibility of an accompaniment intervention designed to improved retention with viral load suppression (i.e., “successful transition”) among a diverse cohort of adolescents living with HIV; (2) pilot study procedures relevant to a future intervention trial; and (3) conduct a retrospective chart review to collect data to inform recruitment and sample size calculations for a future intervention trial.

项目摘要/摘要 对成人艾滋病毒护理的过渡通常是通过降低药物依从性，保留率，艾滋病毒病毒负荷来实现的 抑制和CD4细胞计数；但是，对于哪些干预措施可能最有效 支持青少年进行此护理过渡。我们将为基于社区的可行性研究 由社区卫生工作者提供的伴奏干预旨在改善健康 秘鲁城市成人护理过渡到成人护理的青少年的结果。我们将（1）进行干预飞行员 确定旨在通过病毒负荷改善保留率的布置干预的可行性 在艾滋病毒的青少年中，抑制（即“成功的过渡”）； （2）试点研究 与未来的干预审判有关的程序； （3）进行回顾性图表审查，以收集数据 告知招聘和样本量计算，以进行未来的干预试验。

项目成果

[Impact of SARS-CoV-2 pandemic on adolescents living with HIV in Lima, Peru].

• DOI: 10.17843/rpmesp.2021.381.6296
• 发表时间: 2021-01
• 期刊: Revista peruana de medicina experimental y salud publica
• 作者: Errea RA;Wong M;Senador L;Ramos A;Ramos K;Galea JT;Lecca L;Sánchez H;Benites C;Franke MF
• 通讯作者: Franke MF

A non-specialist depression care pathway for adolescents living with HIV and transitioning into adult care in Peru: a nested, proof of concept pilot study.

• DOI: 10.1017/gmh.2021.16
• 发表时间: 2021
• 期刊: Global mental health (Cambridge, England)
• 作者: Galea JT;Contreras C;Wong M;Ramos K;Vargas V;Sánchez H;Errea RA;Lecca L;Franke MF
• 通讯作者: Franke MF

Community-based accompaniment for adolescents transitioning to adult HIV care in urban Peru: a pilot study.

• DOI: 10.1007/s10461-022-03725-2
• 发表时间: 2022-12
• 期刊: AIDS and behavior
• 影响因子: 4.4
• 作者: Vargas V;Wong M;Rodriguez CA;Sanchez H;Galea J;Ramos A;Senador L;Kolevic L;Matos E;Sanchez E;Errea RA;Ramos K;Beckhorn C;Lindeborg A;Benites C;Lecca L;Shin S;Franke MF
• 通讯作者: Franke MF

Patient and provider perceptions of a community-based accompaniment intervention for adolescents transitioning to adult HIV care in urban Peru: a qualitative analysis.

• DOI: 10.1002/jia2.26019
• 发表时间: 2022-10
• 期刊: JOURNAL OF THE INTERNATIONAL AIDS SOCIETY
• 影响因子: 6
• 作者: Galea, Jerome T.;Wong, Milagros;Ninesling, Brennan;Ramos, Alicia;Senador, Liz;Sanchez, Hugo;Kolevic, Lenka;Matos, Eduardo;Sanchez, Eduardo;Errea, Renato A.;Lindeborg, Andrew;Benites, Carlos;Lecca, Leonid;Shin, Sonya;Franke, Molly F.
• 通讯作者: Franke, Molly F.